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ClinicalTrials.gov public records Last synced Sep 11, 2026, 5:22 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hydrocephaly Clear all
Recruiting Not applicable Interventional

EVD Drainage Data and Intracranial Pressure (ICP) Measurements

NCT05546996
View directory record Official record
Conditions
Hydrocephalus
Interventions
FlowSense
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
1 Year to 21 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 11, 2026, 5:22 AM EDT
Completed Not applicable Interventional Results available

A Placebo-Controlled Effectiveness in INPH Shunting (PENS) Trial

NCT03350750
View directory record Official record
Conditions
Idiopathic Normal Pressure Hydrocephalus (INPH)
Interventions
programmable CSF shunt valve
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
4
States / cities
Baltimore, Maryland • Albuquerque, New Mexico • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 11, 2026, 5:22 AM EDT
Recruiting No phase listed Observational

Assessment of ShuntCheck Performance Characteristics in Asymptomatic Patients With Normal Pressure Hydrocephalus

NCT04011566
View directory record Official record
Conditions
Hydrocephalus, Normal Pressure
Interventions
ShuntCheck
Diagnostic Test
Lead sponsor
University of South Florida
Other
Eligibility
40 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 11, 2026, 5:22 AM EDT
Completed No phase listed Observational Results available

Assessment of CSF Shunt Flow With Thermal Measurements B

NCT05432986
View directory record Official record
Conditions
Hydrocephalus
Interventions
Thermal Anisotropy Measurement Device
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
Not listed
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
10
States / cities
Oakland, California • San Francisco, California • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Sep 11, 2026, 5:22 AM EDT
Completed Not applicable Interventional Results available

Efficacy in iNPH Shunting (PENS) Trial

NCT05081128
View directory record Official record
Conditions
Idiopathic Normal Pressure Hydrocephalus (INPH)
Interventions
programmable CSF shunt valve
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
14
States / cities
Davis, California • Los Angeles, California • Santa Monica, California + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 11, 2026, 5:22 AM EDT
Completed No phase listed Observational

Magnetic Resonance Imaging (MRI) of Ventriculomegaly: Morphology and Outcome

NCT00870675
View directory record Official record
Conditions
Ventriculomegaly
Interventions
Not listed
Lead sponsor
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
NIH
Eligibility
18 Years and older · Female only
Enrollment
434 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2014 · Synced Sep 11, 2026, 5:22 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

PatientSpot Formerly Known as ArthritisPower

NCT03840928
View directory record Official record
Conditions
Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
Interventions
Not listed
Lead sponsor
Global Healthy Living Foundation
Other
Eligibility
19 Years and older
Enrollment
40,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Upper Nyack, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 11, 2026, 5:22 AM EDT
Completed Not applicable Interventional

A Study Evaluate Aqueduct's Smart External Drain

NCT03113799
View directory record Official record
Conditions
Hydrocephalus, Hydrocephalus in Children, Tumor, Brain
Interventions
Smart External Drain - SED
Device
Lead sponsor
Aqueduct Critical Care
Industry
Eligibility
5 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Sep 11, 2026, 5:22 AM EDT
Completed No phase listed Observational

Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus

NCT00600795
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
CSF collection
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 11, 2026, 5:22 AM EDT
Completed No phase listed Observational

Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life

NCT01367977
View directory record Official record
Conditions
Ehlers Danlos Syndrome, External Hydrocephalus, Dysautonomia, Postural Orthostatic Tachycardia Syndrome, Venous Insufficiency
Interventions
Not listed
Lead sponsor
Genetic Disease Investigators
Other
Eligibility
5 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Colleyville, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Sep 11, 2026, 5:22 AM EDT
Terminated No phase listed Observational

Prognostic Value of Aβ Imaging in NPH Prior to Shunt Placement

NCT01834625
View directory record Official record
Conditions
Normal Pressure Hydrocephalus Patients
Interventions
PET scan
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
60 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Sep 11, 2026, 5:22 AM EDT
Recruiting Phase 1 Interventional

Assessing CSF Flow Dynamics in Pediatric Hemorrhagic Hydrocephalus

NCT06994949
View directory record Official record
Conditions
Post-hemorrhagic Hydrocephalus (PHH)
Interventions
fCTOT cap, NIRF planar imaging, ICG
Device · Drug
Lead sponsor
Eva Sevick
Other
Eligibility
Up to 6 Months
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 11, 2026, 5:22 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Formative Usability Assessment of Wireless Thermal Anisotropy Devices

NCT06040697
View directory record Official record
Conditions
Hydrocephalus
Interventions
Thermal Anisotropy
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
5 Years to 80 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Sep 11, 2026, 5:22 AM EDT
Completed No phase listed Observational

Study of Ultrasound of the Eye for Children With Suspected Shunt Failure

NCT00743457
View directory record Official record
Conditions
Hydrocephalus
Interventions
Ocular Ultrasound
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
6 Months to 18 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 14, 2012 · Synced Sep 11, 2026, 5:22 AM EDT
Terminated No phase listed Observational

People Presenting With Neurocysticercosis in North America

NCT02233855
View directory record Official record
Conditions
Neurocysticercosis
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
4
States / cities
San Francisco, California • Bethesda, Maryland • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 11, 2026, 5:22 AM EDT
Not yet recruiting No phase listed Observational

Bedside Cranial Ultrasound for Risk-Stratified Imaging in Pediatric Acute Brain Injury

NCT07772323
View directory record Official record
Conditions
Acute Brain Injury, Traumatic Brain Injury, Intracranial Hemorrhage, Hydrocephalus, Stroke, Brain Neoplasm, Hypoxia-Ischemia, Brain
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
2 Years to 17 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 11, 2026, 5:22 AM EDT
Completed Not applicable Interventional Results available

Quantitative Characterization of Safe Irrigation for Ventricular Shunt Catheters

NCT02651337
View directory record Official record
Conditions
Hydrocephaly
Interventions
Cerebrospinal Fluid (CSF) Drainage
Device
Lead sponsor
Alcyone Therapeutics, Inc
Industry
Eligibility
30 Days to 35 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 20, 2020 · Synced Sep 11, 2026, 5:22 AM EDT
Not listed Not applicable Interventional

Physician Preference Study of ShuntCheck - Madsen

NCT00583336
View directory record Official record
Conditions
CSF Flow Through the Shunt of a Hydrocephalus Patient
Interventions
ShuntCheck
Device
Lead sponsor
NeuroDx Development
Industry
Eligibility
Up to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 22, 2015 · Synced Sep 11, 2026, 5:22 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies

NCT04020198
View directory record Official record
Conditions
Parkinson Disease, Multiple System Atrophy, Rapid Eye Movement Sleep Behavior Disorder, Normal Pressure Hydrocephalus
Interventions
Biomarker assay
Other
Lead sponsor
Stony Brook University
Other
Eligibility
50 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 11, 2026, 5:22 AM EDT
Active, not recruiting Not applicable Interventional

US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

NCT05232838
View directory record Official record
Conditions
Hydrocephalus, Normal Pressure, Hydrocephalus
Interventions
eShunt Implant
Device
Lead sponsor
CereVasc Inc
Industry
Eligibility
65 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
11
States / cities
New Haven, Connecticut • Jacksonville, Florida • Kansas City, Kansas + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 11, 2026, 5:22 AM EDT
Recruiting Not applicable Interventional

Assessment of CSF Shunt Flow During Activities of Daily Living and Sleep With a Thermal Measurement Device

NCT07050628
View directory record Official record
Conditions
Hydrocephalus
Interventions
wireless thermal anisotropy measurement device
Device
Lead sponsor
Rhaeos, Inc.
Industry
Eligibility
2 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 11, 2026, 5:22 AM EDT
Terminated No phase listed Observational

Micro Ribonucleic Acid (miRNA) Markers of Hydrocephalus in Intraventricular Hemorrhage (IVH)

NCT02386228
View directory record Official record
Conditions
Intraventricular Hemorrhage, Spina Bifida
Interventions
collection of CSF and blood
Genetic
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
Up to 6 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 5, 2017 · Synced Sep 11, 2026, 5:22 AM EDT
Terminated Not applicable Interventional

Pilot Study to Evaluate the CereVasc® EShunt® System in the Treatment of Communicating Hydrocephalus

NCT05501002
View directory record Official record
Conditions
Hydrocephalus, Hydrocephalus, Communicating
Interventions
eShunt® Implant
Device
Lead sponsor
CereVasc Inc
Industry
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
New Haven, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 11, 2026, 5:22 AM EDT
Terminated Not applicable Interventional Results available

Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus

NCT00613886
View directory record Official record
Conditions
Normal Pressure Hydrocephalus
Interventions
Programmable Shunt Insertion (Codman, Medtronic), Assessments in physical therapy, occupational therapy, and speech therapy
Device · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 11, 2026, 5:22 AM EDT