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Showing 1–9 of 9 matching trials from the live ClinicalTrials.gov search.
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Not listed Phase 3 Interventional Accepts healthy volunteers

Droperidol on Prevention of Cannabis Hyperemesis Syndrome

NCT05244460
Conditions
Cannabis Hyperemesis Syndrome
Interventions
Droperidol Injectable Product, Diphenhydramine
Drug
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
4
States / cities
Austintown, Ohio • Boardman, Ohio • Warren, Ohio + 1 more
Conditions
Hyperemesis Gravidarum
Interventions
Gabapentin, Metoclopramide
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Buffalo, New York • Rochester, New York
Conditions
Cyclic Vomiting Syndrome
Interventions
Droperidol, Haloperidol, Ondansetron 8mg
Drug
Lead sponsor
Corewell Health South
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Saint Joseph, Michigan
Conditions
Pregnancy, Severe Nausea and Vomiting, Hyperemesis Gravidarum
Interventions
Mirtazapine
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 49 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy

NCT05098067
Conditions
Hyperemesis Gravidarum, Nausea Gravidarum, Vomiting of Pregnancy
Interventions
Capsaicin Topical Cream, Metoclopramide, Ondansetron, Lactated Ringers, Intravenous
Drug
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Cannabinoid Hyperemesis Syndrome
Interventions
Olanzapine 10 milligram, Haloperidol
Drug
Lead sponsor
Mercy Bon Secours Saint Vincent Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Toledo, Ohio
Conditions
Nausea and Vomiting of Pregnancy
Interventions
doxylamine succinate 10 mg/pyridoxine hydrochloride 10 mg, Placebo
Drug
Lead sponsor
Duchesnay Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland • Pittsburgh, Pennsylvania + 3 more
Conditions
Cannabinoid Hyperemesis Syndrome
Interventions
Capsaicin, Placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Hyperemesis Gravidarum Risk Reduction With Metformin

NCT07129473
Conditions
Hyperemesis Gravidarum
Interventions
Metformin Extended Release Oral Tablet
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
2
States / cities
Birmingham, Alabama • Los Angeles, California