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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hyperglycemia Stress Clear all
Completed Not applicable Interventional Results available

Effect of Dietary Glycemic Index on Beta-cell Function

NCT01386645
View directory record Official record
Conditions
Impaired Glucose Tolerance, Oxidative Stress, Prediabetes, Impaired Fasting Glucose
Interventions
low glycemic index (LGI) diet, high glycemic index (HGI) diet plus placebo (PLAC), high glycemic index diet plus N-acetylcysteine
Other · Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Sep 14, 2026, 9:04 AM EDT
Recruiting Not applicable Interventional

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

NCT06735651
View directory record Official record
Conditions
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female, Adult, Endothelial Function (Reactive Hyperemia), Arterial Stiffness, Cognition, Oxidative Stress, Gut Microbiota, Overweight, Inflammation, Microvascular Function, Body Composition
Interventions
Wild Blueberry, Placebo
Dietary Supplement
Lead sponsor
Georgia State University
Other
Eligibility
20 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 14, 2026, 9:04 AM EDT
Recruiting Not applicable Interventional

Diabetes Clinical Decision Support

NCT05447806
View directory record Official record
Conditions
Hyperglycemia, Hyperglycemia Stress, Diabetes, PreDiabetes, Hypoglycemia
Interventions
Active Electronic Medical Record Inpatient Diabetes Clinical Decision Support
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
15,732 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Hershey, Pennsylvania • Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Phase 2 Interventional

Rosiglitazone to Reverse Metabolic Defects in Diabetes

NCT00094796
View directory record Official record
Conditions
Diabetes Mellitus, Type II, Insulin Resistance
Interventions
Exercise cardiopulmonary metabolic testing, Skeletal muscle biopsy, Brachial artery reactivity testing
Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
22 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
2
States / cities
Bethesda, Maryland • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 14, 2026, 9:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Daily Blood Glucose Trends in Patients at Risk for Diabetes

NCT06000735
View directory record Official record
Conditions
Stress, Blood Sugar; High, Cholesterol, Elevated, Diet Habit
Interventions
7-Day Continuous Glucose Monitoring with Abbott Freestyle Libre 2
Device
Lead sponsor
Karol E. Watson, MD
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Phase 4 Interventional Results available

Comparison of Blood Pressure Medications on Metabolism

NCT00642434
View directory record Official record
Conditions
Diabetes
Interventions
carvedilol, metoprolol
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
45 Years to 85 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Dec 25, 2023 · Synced Sep 14, 2026, 9:04 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications

NCT06765655
View directory record Official record
Conditions
Surgical Site Infections, Stress Hyperglycemia
Interventions
Insulin Lispro Injection, glucose testing
Drug · Diagnostic Test
Lead sponsor
St. Peter's Hospital, Albany, NY
Other
Eligibility
18 Years and older
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 14, 2026, 9:04 AM EDT
Active, not recruiting Not applicable Interventional

The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes

NCT06159543
View directory record Official record
Conditions
Hyperglycemia, Dyslipidemias, Insulin Resistance, Inflammation, Oxidative Stress
Interventions
Mango
Behavioral
Lead sponsor
Loma Linda University
Other
Eligibility
40 Years to 60 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 14, 2026, 9:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Mobile Phone-based Intervention for Promoting Healthy Habits and Weight Loss

NCT02621008
View directory record Official record
Conditions
Diabetes, Hypertension, Pre-diabetes, Overweight, Obese, Weight, Adherence
Interventions
Stress Reduction& Healthy living
Other
Lead sponsor
Eco Fusion
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 31, 2015 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Not applicable Interventional Results available

The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women

NCT04705779
View directory record Official record
Conditions
Heart Diseases, Stroke, Pre-diabetes, Hypertension, Obesity, Overweight, Stress
Interventions
HARMONY, Nutrition and Exercise Education (NEEW)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 14, 2026, 9:04 AM EDT
Terminated Phase 4 Interventional Results available

Perioperative Stress Hyperglycemia in General and Vascular Surgery Patients

NCT04862234
View directory record Official record
Conditions
Hyperglycemia Stress
Interventions
Dulaglutide, Placebo, Continuous glucose monitor (CGM), blinded
Drug · Device
Lead sponsor
Emory University
Other
Eligibility
45 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Regulation of Postprandial Nitric Oxide Bioavailability and Vascular Function By Dairy Fat

NCT02482610
View directory record Official record
Conditions
Prediabetes
Interventions
Glucose, Glucose with Whole Fat Milk, Glucose with Non-fat Milk
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 28, 2019 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Emotion-Diet Interactions in Pregnancy

NCT04430439
View directory record Official record
Conditions
Pregnancy Related, Stress, Psychological, Glucose Intolerance During Pregnancy, Emotional Stress, Postprandial Hyperglycemia, Insulin Sensitivity/Resistance
Interventions
Psychosocial stress, Control non-stress
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Irvine, California • Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 14, 2026, 9:04 AM EDT
Terminated Not applicable Interventional

Hyperglycemia and Oxidative Stress in the Human Brain With Diabetes

NCT00775541
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Vitamin C
Dietary Supplement
Lead sponsor
In-Young Choi, Ph.D.
Other
Eligibility
30 Years to 55 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2012 · Synced Sep 14, 2026, 9:04 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Pioglitazone Treatment for Hyperglycemic Acute Ischemic Stroke

NCT04123067
View directory record Official record
Conditions
Stroke, Acute, Hyperglycemia, Diabetes
Interventions
Pioglitazone 45 mg, Placebo oral tablet
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Not applicable Interventional

Mindfulness Training and Group Counseling Among Prediabetes and Diabetes Patients

NCT04702477
View directory record Official record
Conditions
Stress, Diabetes, Pre-Diabetes, Health Behavior, Quality of Life
Interventions
Mindfulness Based Stress Reduction
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 10, 2021 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Phase 4 Interventional Results available

Sitagliptin in Non-Diabetic Patients Undergoing General Surgery

NCT02741687
View directory record Official record
Conditions
Hyperglycemia
Interventions
Sitagliptin, Placebo, Supplemental insulin (insulin lispro), Supplemental insulin (insulin aspart), Long acting basal insulin (insulin detemir), Long acting basal insulin (insulin glargine)
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Sep 14, 2026, 9:04 AM EDT
Completed No phase listed Observational

Assessment of Markers of Stress in Acute Ischemic Stroke With Hyperglycemia

NCT03318679
View directory record Official record
Conditions
Ischemic Stroke, Hyperglycemia
Interventions
No intervention is planned.
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 100 Years
Enrollment
88 participants
Timeline
2017 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Sep 14, 2026, 9:04 AM EDT
Terminated No phase listed Observational

Study of Stress Hyperglycemia as an Indicator of Diabetes Mellitus

NCT02068989
View directory record Official record
Conditions
Stress Hyperglycemia, Diabetes Mellitus Type 2
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
New Haven, Connecticut • Norwalk, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2016 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Glycemic Effects of Honey

NCT01371266
View directory record Official record
Conditions
Pre-diabetes
Interventions
Honey, High Fructose Corn Syrup 55 (HFCS 55), CHO (sugar)
Dietary Supplement
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
20 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Phase 4 Interventional Results available

Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery

NCT02443402
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Sitagliptin, Placebo, Regular Human Insulin, Insulin glargine, Supplemental insulin (Insulin lispro), Supplemental insulin (Insulin aspart)
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
4
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Sep 14, 2026, 9:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women

NCT07111026
View directory record Official record
Conditions
Occupational Stress, Gender Related Stress, Social Isolation, Hypertension, Pre Diabetes, Diabetes, Obesity
Interventions
Sisters for Heart Health, Basic intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Ellenton, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Not applicable Interventional

Effect of a Low Advanced Glycation End Products (AGE) Diet in the Metabolic Syndrome

NCT01363141
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Regular AGE Diet, Low AGE Diet
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
50 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2015 · Synced Sep 14, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Regulation of Postprandial Nitric Oxide Bioavailability and Vascular Function By Dairy Milk

NCT02482675
View directory record Official record
Conditions
Prediabetes
Interventions
Glucose, Glucose with Non-fat Milk, Glucose with Whey Protein Isolate, Glucose with Sodium Caseinate
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Sep 14, 2026, 9:04 AM EDT