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ClinicalTrials.gov public records Last synced Oct 27, 2026, 6:04 AM EDT

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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hyperhydrosis Clear all
Completed No phase listed Observational

Assessing the Effect of Patient Characteristics on Treatment Response in Primary Hyperhidrosis

NCT03694093
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Not listed
Lead sponsor
St. Louis University
Other
Eligibility
12 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Use of Microneedles With Topical Botulinum Toxin for Treatment of Palmar Hyperhidrosis

NCT03203174
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Microneedle, Sham Microneedle, Botulinum Toxin Type A, Saline
Device · Drug · Other
Lead sponsor
University of California, Davis
Other
Eligibility
12 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2017 · Synced Oct 27, 2026, 6:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Image Guided Targeted Photoablation for the Treatment of Localized Hyperhidrosis

NCT04178161
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Laser treatment
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy of Botulinum Toxin Type A Topical Gel for Primary Axillary Hyperhidrosis

NCT02565732
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Botulinum toxin type A, Placebo comparator
Biological
Lead sponsor
Revance Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2016 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Results available

A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 Gel in Subjects With Palmar Hyperhidrosis

NCT02682238
View directory record Official record
Conditions
Hyperhidrosis
Interventions
BBI-4000, 15%, Vehicle gel
Drug · Other
Lead sponsor
Botanix Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
5
States / cities
San Diego, California • Miami, Florida • Carmel, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Terazosin

NCT00449683
View directory record Official record
Conditions
Hyperhidrosis
Interventions
terazosin
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2016 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy of an Anticholinergic Agent for Treatment of Primary Axillary Hyperhidrosis

NCT02193139
View directory record Official record
Conditions
Hyperhidrosis
Interventions
WL8713, 6 mg, WL8713, 12 mg, WL8713, 18 mg, WL8713, 24 mg, Placebo
Drug
Lead sponsor
Watson Pharmaceuticals
Industry
Eligibility
18 Years to 55 Years
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2015 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Results available

A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

NCT02336503
View directory record Official record
Conditions
Hyperhidrosis
Interventions
BBI-4000 Gel, 5%, BBI-4000 Gel, 10%, BBI-4000 Gel, 15%, Vehicle
Drug
Lead sponsor
Botanix Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
12
States / cities
Fremont, California • San Diego, California • Aventura, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Results available

Clinical Trial To Evaluate ANT-1207 In Participants With Primary Axillary Hyperhidrosis

NCT02479139
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Vehicle, ANT-1207
Biological
Lead sponsor
Allergan
Industry
Eligibility
18 Years to 70 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
19
States / cities
Hialeah, Florida • Miami, Florida • Pinellas Park, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2017 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Not applicable Interventional

Histological Analysis Following Ulthera System Treatment for Hyperhidrosis

NCT01708551
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated Dec 14, 2017 · Synced Oct 27, 2026, 6:04 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

BTX-A Treatment for Palmar Hyperhidrosis

NCT01262339
View directory record Official record
Conditions
Primary Focal Hyperhidrosis of the Hands
Interventions
BTX-A
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
16 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 26, 2015 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Botox and Suction-Curettage for Treatment of Excessive Underarm Sweating (Axillary Hyperhidrosis)

NCT01274611
View directory record Official record
Conditions
Axillary Hyperhidrosis
Interventions
Botulinum Toxin Type A, Suction-Curettage
Drug · Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 6, 2021 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Results available

Pharmacokinetic, Safety, Tolerability, and Clinical Effect of Topical Umeclidinium in Primary Axillary Hyperhidrosis

NCT02563899
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Umeclidinium, Vehicle
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Raleigh, North Carolina • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

An Open Label Study for Palmar Hyperhydrosis

NCT04906655
View directory record Official record
Conditions
Palmar Hyperhidrosis, Hyperhidrosis, Sweat Gland Diseases, Skin Diseases
Interventions
Glycopyrronium 2.4 % Medicated Cloth
Drug
Lead sponsor
Pariser, Robert J., M.D.
Other
Eligibility
9 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Not applicable Interventional

Feasibility Study: Safety and Efficacy of the Ulthera® System for Treatment of Axillary Hyperhidrosis

NCT01713673
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Ulthera System Treatment, Sham treatment
Drug
Lead sponsor
Ulthera, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 3 Interventional Results available

Study of Glycopyrronium in Axillary Hyperhydrosis

NCT02530281
View directory record Official record
Conditions
Hyperhidrosis
Interventions
glycopyrronium Topical Wipes, Vehicle
Drug · Other
Lead sponsor
Journey Medical Corporation
Industry
Eligibility
9 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
21
States / cities
Mobile, Alabama • Encinitas, California • San Diego, California + 18 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 27, 2026, 6:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of Safety and Efficacy of Morpheus8 Applicator for the Treatment of Focal Hyperhidrosis of the Axillae Using Radio Frequency

NCT05860972
View directory record Official record
Conditions
Hyperhidrosis Primary Focal Axilla
Interventions
Morpheus8 Applicator (with the 24 pin tip) in the treatment of primary axillary hyperhidrosis.
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
New York, New York • Knoxville, Tennessee • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2024 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Not applicable Interventional Results available

Evaluation of 1440nm Laser Assisted Selective Photothermolysis for Treatment of Axillary Hyperhidrosis

NCT02100072
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Nd:YAG 1440 nm laser
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 8, 2021 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy Study of Sofpironium Bromide in Subjects With Axillary Hyperhidrosis (BBI-4000-CL-302)

NCT03948646
View directory record Official record
Conditions
Axillary Hyperhidrosis
Interventions
Sofpironium Bromide, 15%, Vehicle
Drug
Lead sponsor
Botanix Pharmaceuticals
Industry
Eligibility
9 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
42
States / cities
Birmingham, Alabama • Glendale, Arizona • North Little Rock, Arkansas + 35 more
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate Clinical Effect, Pharmacokinetics , Safety, and Tolerability of Umeclidinium in Palmar Hyperhidrosis Subjects

NCT02673619
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Umeclidinium, Vehicle
Drug
Lead sponsor
Stiefel, a GSK Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
5
States / cities
Omaha, Nebraska • Raleigh, North Carolina • Austin, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2018 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 2 Interventional Results available

Comparator Study of the Effect of Glycopyrrolate and Glycopyrronium in Subjects With Axillary Hyperhidrosis

NCT02129660
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Dose 1 of glycopyrrolate, 2.0% QD, Dose 2 of glycopyrrolate, 3.0% QD, Dose 1 of glycopyrronium, 2.5% QD, Dose 2 of glycopyrronium, 3.75% QD, Vehicle
Drug · Other
Lead sponsor
Journey Medical Corporation
Industry
Eligibility
18 Years to 99 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
14
States / cities
Encinitas, California • Fremont, California • Tampa, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Phase 1 Interventional

Hyperhidrosis, Developing a Treatment Approach Aims 1 & 2

NCT03416348
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Aluminum Chloride 20% (deodorant), Alcohol
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating

NCT00509886
View directory record Official record
Conditions
Hyperhidrosis, Excess Sweating
Interventions
Drysol, Drioff
Drug
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 30 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 10, 2014 · Synced Oct 27, 2026, 6:04 AM EDT
Completed Not applicable Interventional

Pilot Study of Terazosin in Treatment of Antidepressant Induced Excessive Sweating

NCT00237510
View directory record Official record
Conditions
Antidepressant Induced Excessive Sweating
Interventions
terazosin
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2014 · Synced Oct 27, 2026, 6:04 AM EDT