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ClinicalTrials.gov public records Last synced Nov 7, 2026, 9:58 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 847 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Hyperlipidaemia Clear all

Conditions: Obesity
Interventions: LLF580, Placebo; Biological · Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 7
States / cities: Jacksonville, Florida • Miami, Florida • Overland Park, Kansas + 4 more

Conditions: Familial Hypercholesterolemia
Interventions: Testing centralized referral mechanism for PCPs, Inviting patients to complete a telehealth appointment with a lipid specialist for an FH evaluation; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 610 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Homozygous Familial Hypercholesterolemia
Interventions: REGN1500 250 mg SC/15 mg/kg IV/450 mg SC; Drug
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 3
States / cities: Los Angeles, California • Philadelphia, Pennsylvania • Dallas, Texas

Conditions: Hypertriglyceridemia
Interventions: Docosahexenoic acid (DHA), Olive oil; Dietary Supplement
Lead sponsor: USDA, Western Human Nutrition Research Center; Federal
Eligibility: 39 Years to 66 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Davis, California

Conditions: Hypercholesterolemia, LDL Cholesterol
Interventions: LGT209 50 mg, LGT209 300 mg, Placebo, Statins (atorvastatin or simvastatin); Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 2
States / cities: Fort Myers, Florida • Miramar, Florida

Conditions: Diabetes, Depression, Cardiovascular Disease,Hypercholesterolemia, Osteoporosis
Interventions: Active Implementation of ShareEBM Toolkit, Passive Dissemination of Share EBM; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 12
States / cities: Brooklyn Center, Minnesota • Delano, Minnesota • Duluth, Minnesota + 8 more

Conditions: Hypercholesterolemia, Obesity
Interventions: Pecan ADD, Pecan SUB; Dietary Supplement
Lead sponsor: University of Georgia; Other
Eligibility: 30 Years to 75 Years
Enrollment: 124 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Athens, Georgia

Conditions: Healthy Volunteers; High Cholesterol
Interventions: NNC0385-0434 G, NNC0385-0434 F, NNC0385-0434 B; Drug
Lead sponsor: Novo Nordisk A/S; Industry
Eligibility: 18 Years to 64 Years · Male only
Enrollment: 152 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 2
States / cities: Cypress, California • Los Angeles, California

Conditions: Primary Hypercholesterolemia, Mixed Dyslipidemia
Interventions: Evolocumab AMD, Evolocumab AI/pen; Biological
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2013
U.S. locations: 22
States / cities: Phoenix, Arizona • Encino, California • Thousand Oaks, California + 18 more

Conditions: Hyperlipidemia
Interventions: Uncle Sam Cereal; Dietary Supplement
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Hypertriglyceridemia
Interventions: Gemfibrozil; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 19 Years to 74 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Metabolic Syndrome X, Insulin Resistance, Hypertension, Hypercholesterolemia, Obesity
Interventions: Exercise, Metformin; Behavioral · Drug
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 20 Years to 55 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Hypercholesterolemia
Interventions: CIVI 007; Drug
Lead sponsor: Civi Biopharma, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 7
States / cities: Jacksonville, Florida • Port Orange, Florida • Indianapolis, Indiana + 4 more

Conditions: Atherosclerosis, Coronary Artery Disease
Interventions: lovastatin; Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 21 Years to 67 Years
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1985 – 1992
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Diabetes Mellitus, Dyslipidemia, Hypercholesterolemia, Cardiovascular Disease
Interventions: Decision Aid Statin Choice; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obesity, Hypertension, Hyperlipidemias, Diet Modification
Interventions: In-store POP education, Online POP education; Other
Lead sponsor: University of Cincinnati; Other
Eligibility: 21 Years to 75 Years
Enrollment: 267 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Hypertriglyceridmia
Interventions: Diazoxide Choline Controlled-Release Tablet; Drug
Lead sponsor: Essentialis, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Hyperlipidemia
Interventions: torcetrapib/atorvastatin, atorvastatin, placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years and older
Enrollment: 3,800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 96
States / cities: Mobile, Alabama • Mesa, Arizona • Oro Valley, Arizona + 93 more

Conditions: Hypertriglyceridemia, Diabetic Neuropathy
Interventions: omega-3-ethyl esters, Placebo; Drug
Lead sponsor: Eastern Virginia Medical School; Other
Eligibility: 18 Years to 80 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Chronic Kidney Diseases, High Cholesterol
Interventions: Evolocumab, Placebo; Drug · Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 40 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 2
States / cities: Mineola, New York • New York, New York

Conditions: Hypercholesterolemia
Interventions: stage-matched intervention, framing effects intervention, attention placebo intervention; Behavioral
Lead sponsor: Narrows Institute for Biomedical Research; Other
Eligibility: 21 Years and older
Enrollment: 247 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: High Cholesterol, High Blood Pressure, Colorectal Cancer, Breast Cancer, Prostate Cancer
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 30 Years to 75 Years
Enrollment: 539 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hypertriglyceridemia, Obesity
Interventions: Setmelanotide; Drug
Lead sponsor: Rhythm Pharmaceuticals, Inc.; Industry
Eligibility: 15 Years to 15 Years · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Social Determinants of Health (SDOH), Hypertension, Diabetes Mellitus, Hypercholesterolaemia
Interventions: Community Health Worker intervention, Usual Care; Other
Lead sponsor: Sairam Parthasarathy; Other
Eligibility: 18 Years and older
Enrollment: 740 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Tucson, Arizona

Search by objective public record fields.

Safety Study of LLF580 in Obese Volunteers

Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics

Study of REGN1500 in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Docosahexenoic Acid (DHA) Supplementation and Cardiovascular Disease in Men With High Triglycerides

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Use of Decision Aids in Clinical Encounters

Diets Enriched With Pecans

A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation II

Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen

A Controlled Trial of High Dietary Fiber Intake on Serum Lipids

Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides

Physical Inactivity and Insulin Resistance in Skeletal Muscle.

Phase 2a Study to Assess CIVI 007 in Patients on a Background of Statin Therapy

MARS - Monitored Atherosclerosis Regression Study

Effect of a Decision Aid About Statin Use in Patients With Type 2 Diabetes Mellitus

Supermarket and Web-Based Intervention Targeting Nutrition (SuperWIN) for Cardiovascular Risk Reduction

Pharmacokinetic Study of Diazoxide Choline in Hypertriglyeridemic Subjects

A Study of Torcetrapib/Atorvastatin vs Atorvastatin Alone or Placebo in Patients With High Cholesterol

Lovaza® and Microvascular Function in Type 2 Diabetes

Evolocumab In Advanced Chronic Kidney Disease Trial

TACTICS (Targeting Adherence to Cholesterol-lowering Therapy to Improve Control Study)

Online Trial Examining Validity and Reliability of the Shared Decision Making Process Survey

Setmelanotide in a Single Patient With Partial Lipodystrophy

Arizona CEAL: Linking Social Care With Healthcare Systems to Address SDOH