- Conditions
- Hyperoxia
- Interventions
- FiO2 titration using electronic alert system
- Other
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 936 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
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Showing 25–37
of 13
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Trauma, Critical Illness, Oxygen Toxicity
- Interventions
- Targeted Normoxia (oxygen saturation 90-96%), Usual Care Oxygenation
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 109 Years
- Enrollment
- 572 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Critical Illness, Wounds and Injury, Disease Attributes, Pathologic Processes
- Interventions
- Targeting Normoxemia (SpO2 90-96%; PaO2 60-100 mmHg)
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 120 Years
- Enrollment
- 6,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • Denver, Colorado • Cincinnati, Ohio + 5 more
- Conditions
- Traumatic Brain Injury
- Interventions
- Hyperbaric Oxygen Treatment (HBOT), Enhanced Oxygen Treatment (Enhanced FiO2)
- Procedure
- Lead sponsor
- Hennepin Healthcare Research Institute
- Other
- Eligibility
- 16 Years to 65 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2008
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Retinal Ischemia
- Interventions
- Hyperoxia
- Drug
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Cardiac Surgery
- Interventions
- Continuous low-tidal volume ventilation with using FiO2 of 0.21, Continuous low tidal volume ventilation with using FiO2 of 1.0, Apnea During CPB
- Other
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5,502 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Critical Illness, Wounds and Injury, Disease Attributes, Pathologic Processes
- Interventions
- Automated Titration (O2matic)
- Device
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 4
- States / cities
- Aurora, Colorado • Winston-Salem, North Carolina • Portland, Oregon + 1 more
- Conditions
- Stroke, Acute
- Interventions
- Oxygen, placebo
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Colorado Springs, Colorado
- Conditions
- Traumatic Spinal Cord Injuries
- Interventions
- Normobaric Hyperoxia
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Retinopathy of Prematurity
- Interventions
- Not listed
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 1 Day to 12 Months
- Enrollment
- 102 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Respiratory Failure
- Interventions
- Normoxia with Normocarbia, Normoxia with Hypercarbia, Hyperoxia with Normocarbia, Hyperoxia with Hypercarbia
- Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Hyperoxia, Hypoxia, Brain, Neurobehavioral Manifestations
- Interventions
- Oxygen
- Drug
- Lead sponsor
- Case Western Reserve University
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Sleep Apnea, Elderly Adults
- Interventions
- Hyperoxia/oxygen, Acetazolamide, Finasteride
- Other · Drug
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 60 Years to 89 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2027
- U.S. locations
- 1
- States / cities
- Detroit, Michigan