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ClinicalTrials.gov public records Last synced Jun 11, 2026, 5:29 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hypertension; Maternal Clear all
Completed Not applicable Interventional Results available

The CHIPS Trial (Control of Hypertension In Pregnancy Study)

NCT01192412
View directory record Official record
Conditions
Gestational Hypertension
Interventions
Intervention is blood pressure management approach.
Procedure
Lead sponsor
University of British Columbia
Other
Eligibility
Female only
Enrollment
987 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
11
States / cities
New Haven, Connecticut • Louisville, Kentucky • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Jun 11, 2026, 5:29 AM EDT
Completed Not applicable Interventional

Randomized Clinical Trial to Increase Physical Activity After a a Hypertensive Pregnancy

NCT04119232
View directory record Official record
Conditions
Hypertension in Pregnancy, Preeclampsia, Gestational Hypertension
Interventions
Social incentives-based program
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 13, 2020 · Synced Jun 11, 2026, 5:29 AM EDT
Recruiting No phase listed Observational

EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)

NCT06249178
View directory record Official record
Conditions
Preeclampsia
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 28, 2025 · Synced Jun 11, 2026, 5:29 AM EDT
Recruiting Phase 2 Interventional

Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia

NCT02989025
View directory record Official record
Conditions
Pregnancy, Preeclampsia (PE)
Interventions
17 OHPC
Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 11, 2026, 5:29 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Clinical Trial of a COX-2 Inhibitor for the Treatment of Women With Preeclampsia

NCT00442676
View directory record Official record
Conditions
Preeclampsia
Interventions
Celecoxib, Placebo
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 12, 2012 · Synced Jun 11, 2026, 5:29 AM EDT
Completed Not applicable Interventional Results available

Accuracy Assessment of an Automatic Blood Pressure Measurement Device in Pregnant Women

NCT02319174
View directory record Official record
Conditions
Pre Eclampsia
Interventions
Sphygmo
Device
Lead sponsor
William Marsh Rice University
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Jun 11, 2026, 5:29 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Treatment of Elevated Blood Pressures in Early Pregnancy

NCT05955040
View directory record Official record
Conditions
Elevated Blood Pressure, Pregnancy Induced Hypertension
Interventions
Nifedipine, Labetalol
Drug
Lead sponsor
Marshall University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Jun 11, 2026, 5:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Placental Growth and Adverse Pregnancy Outcomes

NCT01669525
View directory record Official record
Conditions
Hypertension Induced by Pregnancy, Pre-Eclampsia, IUGR
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
Female only
Enrollment
1,043 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Jun 11, 2026, 5:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Modernized Approach to Prenatal Care in Low Risk Women

NCT01606774
View directory record Official record
Conditions
Pre-eclampsia, Intrauterine Growth Retardation
Interventions
Modernized prenatal care
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Up to 35 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Jun 11, 2026, 5:29 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Endothelial Progenitor Cells in Umbilical Cord Blood in Preeclampsia and IUGR

NCT00634855
View directory record Official record
Conditions
Preeclampsia, IUGR
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Jun 11, 2026, 5:29 AM EDT
Withdrawn Not applicable Interventional

Lisinopril for Renal Protection in Postpartum Preeclamptic Women

NCT05016440
View directory record Official record
Conditions
Microalbuminuria, Preeclampsia
Interventions
Lisinopril
Drug
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 22, 2021 · Synced Jun 11, 2026, 5:29 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Preeclampsia: A Marker for Future Cardiovascular Risk in Women

NCT01519297
View directory record Official record
Conditions
Preeclampsia, Pregnancy Induced Hypertension
Interventions
Irbesartan
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Jun 11, 2026, 5:29 AM EDT
Recruiting Phase 4 Interventional

Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial

NCT05309460
View directory record Official record
Conditions
Postpartum Preeclampsia, Hypertension in Pregnancy
Interventions
Labetalol Oral Tablet, NIFEdipine ER
Drug
Lead sponsor
Nebraska Methodist Health System
Other
Eligibility
19 Years and older · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Jun 11, 2026, 5:29 AM EDT
Completed Phase 4 Interventional Results available

Use of Nitrous Oxide Donor for Labor Induction in Women With PreEclampsia

NCT03171480
View directory record Official record
Conditions
Preeclampsia, Labor, Premature
Interventions
Monoket Pill, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Jun 11, 2026, 5:29 AM EDT
Not listed Phase 3 Interventional

Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide

NCT03298802
View directory record Official record
Conditions
Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced, Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Interventions
Hydrochlorothiazide 50mg Tablet, Placebo Tablet
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
612 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Austin, Texas • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Jun 11, 2026, 5:29 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

A Comparison of Compliance Between Clonidine Patch and Methyldopa for the Treatment of Chronic Hypertension in Pregnancy

NCT00329511
View directory record Official record
Conditions
Hypertension
Interventions
methyldopa vs. clonidine, clonidine patch
Drug
Lead sponsor
Afshan B. Hameed, M.D.
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Jun 11, 2026, 5:29 AM EDT
Enrolling by invitation No phase listed Observational

Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines

NCT06576544
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication, Postpartum Pre-Eclampsia, Cardiovascular Diseases, Cardiovascular Morbidity, Morbidity;Perinatal
Interventions
BP Watch
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Jun 11, 2026, 5:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Deep Breathing Techniques (Pranayama) in Pregnancy

NCT05341921
View directory record Official record
Conditions
Pregnancy Related, Hypertension in Pregnancy, Blood Pressure
Interventions
Alternate Nostril Breathing, Bhramari Breathing, Sheetali Breathing
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
18 Years and older · Female only
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Merriam, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 19, 2025 · Synced Jun 11, 2026, 5:29 AM EDT
Completed No phase listed Observational

Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension

NCT05881252
View directory record Official record
Conditions
Maternal Hypertension
Interventions
Clinical blood pressure threshold of SBP >= 160 mmHg for acute treatment of hypertension, Clinical blood pressure threshold of SBP >= 180 mmHg for acute treatment of hypertension
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Female only
Enrollment
1,003 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Jun 11, 2026, 5:29 AM EDT
Completed Phase 2 Interventional Results available

Furosemide for Accelerated Recovery of Blood Pressure Postpartum

NCT03556761
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced
Interventions
Oral furosemide, Placebo Oral Tablet
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Jun 11, 2026, 5:29 AM EDT
Completed Phase 4 Interventional Results available

Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension

NCT05049616
View directory record Official record
Conditions
Hypertension in Pregnancy, Postpartum Preeclampsia
Interventions
ACE Inhibitors and Diuretics, NIFEdipine ER
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jun 11, 2026, 5:29 AM EDT
Withdrawn Not applicable Interventional

Docosahexaenoic Acid Supplementation of Women With Hypertension in Pregnancy to Improve Endothelial Health

NCT02137408
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Docosahexaenoic acid 200 mg, Docosahexaenoic acid 1000 mg
Dietary Supplement · Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 17, 2014 · Synced Jun 11, 2026, 5:29 AM EDT
Terminated Phase 4 Interventional

Metformin and Esomeprazole in Preterm Pre-eclampsia

NCT06359015
View directory record Official record
Conditions
Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, Preterm
Interventions
Metformin, Esomeprazole
Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Jun 11, 2026, 5:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Delivering HOPE (Helping Women Optimize Prenatal Equity)

NCT06814509
View directory record Official record
Conditions
Gestational Weight Gain, Diet, Healthy, Gestational Hypertension, Gestational Diabetes, Pregnancy Complications
Interventions
Enhanced Standard of Care (ESoC), Delivering HOPE
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
16 Years to 44 Years · Female only
Enrollment
1,440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
8
States / cities
Corning, Arkansas • Lavaca, Arkansas • Marianna, Arkansas + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jun 11, 2026, 5:29 AM EDT