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ClinicalTrials.gov public records Last synced Oct 1, 2026, 9:47 PM EDT

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Showing 97–120 of 269 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hypertension; Maternal Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Magnesium Sulfate in Obese Preeclamptics

NCT02835339
View directory record Official record
Conditions
Preeclampsia
Interventions
Magnesium sulfate 4g loading dose, 1g/hr infusion, Magnesium sulfate 6g loading dose, 2g/hr infusion
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Oct 1, 2026, 9:47 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Predictors of Aspirin Failure in Preeclampsia Prevention

NCT05709483
View directory record Official record
Conditions
Preeclampsia
Interventions
Aspirin
Drug
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 1, 2026, 9:47 PM EDT
Terminated Phase 4 Interventional Results available

Postpartum Hypertension Study

NCT05139238
View directory record Official record
Conditions
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Pregnancy-Induced Hypertension in Postpartum, Hypertensive Emergency
Interventions
Labetalol, Nifedipine
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 1, 2026, 9:47 PM EDT
Enrolling by invitation No phase listed Observational

Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines

NCT06576544
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication, Postpartum Pre-Eclampsia, Cardiovascular Diseases, Cardiovascular Morbidity, Morbidity;Perinatal
Interventions
BP Watch
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 1, 2026, 9:47 PM EDT
Completed Not applicable Interventional

Innovation in Postpartum Care for Women With Hypertensive Disorders of Pregnancy

NCT03613714
View directory record Official record
Conditions
Hypertension in Pregnancy, Hypertension, Pregnancy-Induced, Postpartum Preeclampsia, Blood Pressure Disorders
Interventions
At-home Blood Pressure Monitoring
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 1, 2026, 9:47 PM EDT
Terminated Phase 4 Interventional Results available

Persistent Postpartum Hypertension Pilot Trial

NCT04349124
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Nifedipine Extended-Release Tablets
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Oct 1, 2026, 9:47 PM EDT
Completed No phase listed Observational

The Study of Cardiovascular Outcomes in Women With Preeclampsia Using Echocardiography: The SCOPE Study

NCT02357667
View directory record Official record
Conditions
Preeclampsia
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 1, 2026, 9:47 PM EDT
Completed Not applicable Interventional

Supporting Transitions to Primary Care Among Under-resourced, Postpartum Women (STEP-UP)

NCT05852054
View directory record Official record
Conditions
Gestational Diabetes Mellitus, Hypertension in Pregnancy, Dysglycemia
Interventions
OB Provider Clinical Decision Support (CDS), Patient Education (OB Visit), Text messaging, Patient Outreach, Primary Care Provider Clinical Decision Support (CDS), Patient Education (Primary Care Visit)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
2,306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 1, 2026, 9:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy

NCT02755831
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, Pre-natal care
Device · Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older · Female only
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 1, 2026, 9:47 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Mechanisms of Pregnancy Vascular Adaptations

NCT03806283
View directory record Official record
Conditions
Pre-Eclampsia, Vascular Diseases
Interventions
Omental Biopsy
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 1, 2026, 9:47 PM EDT
Terminated Phase 3 Interventional Results available

Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide

NCT03298802
View directory record Official record
Conditions
Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced, Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Interventions
Hydrochlorothiazide 50mg Tablet, Placebo Tablet
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
453 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
2
States / cities
Austin, Texas • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 1, 2026, 9:47 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Preeclampsia Registry

NCT06377878
View directory record Official record
Conditions
Preeclampsia, Eclampsia, HELLP Syndrome, Toxemia, Hypertensive Disorder of Pregnancy
Interventions
Not listed
Lead sponsor
Preeclampsia Foundation
Other
Eligibility
13 Years and older
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2040
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Oct 1, 2026, 9:47 PM EDT
Completed Not applicable Interventional

Remote Monitoring and Follow-up for Postpartum Hypertensive Disorders of Pregnancy

NCT05124327
View directory record Official record
Conditions
Hypertensive Disorder of Pregnancy, Preeclampsia, Gestational Hypertension
Interventions
QI project- usage of RPM
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 1, 2026, 9:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prenatal Mindfulness & Hypertension Study

NCT03679117
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Mindfulness Training
Behavioral
Lead sponsor
Lifespan
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 1, 2023 · Synced Oct 1, 2026, 9:47 PM EDT
Not yet recruiting Not applicable Interventional

Remote Patient Monitoring for Chronic Hypertension During Pregnancy (REACH)

NCT07115199
View directory record Official record
Conditions
Chronic Hypertension in Pregnancy
Interventions
Remote Patient Monitoring
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 1, 2026, 9:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of BNP Levels Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women

NCT02527018
View directory record Official record
Conditions
Preeclampsia, Maternal, Hypertension, Pregnancy
Interventions
Sphygmomanometer
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 1, 2026, 9:47 PM EDT
Recruiting No phase listed Observational

Examining Digital Health Care Delivery Models Through Medicaid Collaborative

NCT05555095
View directory record Official record
Conditions
Hypertension, Diabetes Mellitus, Maternal Health
Interventions
digital health delivered multicomponent intervention
Behavioral
Lead sponsor
OSF Healthcare System
Other
Eligibility
18 Years and older
Enrollment
19,331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Oct 1, 2026, 9:47 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Utilization of Somatic Tissue Oxygen Saturation Monitoring in Pregnant Women

NCT03196141
View directory record Official record
Conditions
Pre-Eclampsia
Interventions
StO2 and EndoPAT
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 12, 2019 · Synced Oct 1, 2026, 9:47 PM EDT
Active, not recruiting Not applicable Interventional

Mindfulness & Mechanisms Study

NCT04626245
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Mindfulness training
Behavioral
Lead sponsor
Lifespan
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 1, 2026, 9:47 PM EDT
Terminated Phase 2 Interventional

L-Arginine and Antioxidant Vitamins During Pregnancy to Reduce Preeclampsia

NCT00469846
View directory record Official record
Conditions
Pre-Eclampsia
Interventions
L-arginine supplementation in a medical food, Vitamin C and E supplementation in a medical food
Procedure
Lead sponsor
Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Government
Eligibility
19 Years to 32 Years · Female only
Enrollment
585 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2007 · Synced Oct 1, 2026, 9:47 PM EDT
Completed Not applicable Interventional Results available

Remote BP Monitoring in the PP Period

NCT03728790
View directory record Official record
Conditions
Hypertensive Disorder of Pregnancy
Interventions
Remote Patient Monitoring
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 1, 2025 · Synced Oct 1, 2026, 9:47 PM EDT
Completed Phase 3 Interventional Results available

Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia

NCT02059135
View directory record Official record
Conditions
Preeclampsia
Interventions
Recombinant human antithrombin (ATryn), Normal Saline 0.9%
Biological · Other
Lead sponsor
rEVO Biologics
Industry
Eligibility
16 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
23
States / cities
Birmingham, Alabama • Mobile, Alabama • Little Rock, Arkansas + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2017 · Synced Oct 1, 2026, 9:47 PM EDT
Not listed Not applicable Interventional

Virtual Cardiac Wellness Program Following Hypertensive Disorders of Pregnancy

NCT04998942
View directory record Official record
Conditions
Hypertension in Pregnancy, Gestational Hypertension, Preeclampsia, Chronic Hypertension With Pre-Eclampsia, Eclampsia, Chronic Hypertension in Obstetric Context
Interventions
virtual cardiac wellness program, Placebo comparator
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 1, 2026, 9:47 PM EDT
Recruiting Early Phase 1 Interventional

Daily Aspirin Treatment After Preeclampsia

NCT06168461
View directory record Official record
Conditions
Preeclampsia
Interventions
Aspirin, Placebo
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 1, 2026, 9:47 PM EDT