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ClinicalTrials.gov public records Last synced Nov 7, 2026, 2:01 PM EST

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Showing 2233–2256 of 3,919 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hypertension Clear all
Terminated Phase 1Phase 2 Interventional Results available

Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Pulmonary Hypertension

NCT01479010
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Anakinra 100 mg subcutaneously daily
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Nov 7, 2026, 2:01 PM EST
Completed Not applicable Interventional

Medication Adherence in Hypertension Study

NCT00688350
View directory record Official record
Conditions
Hypertension
Interventions
Behavioral feedback
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
60 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Nov 7, 2026, 2:01 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Analyzing Genes That May Increase the Risk of Developing High Blood Pressure

NCT00549991
View directory record Official record
Conditions
Hypertension
Interventions
Not listed
Lead sponsor
Case Western Reserve University
Other
Eligibility
21 Years and older
Enrollment
8,687 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Nov 7, 2026, 2:01 PM EST
Completed Not applicable Interventional

Cut Your Blood Pressure 3

NCT03726710
View directory record Official record
Conditions
Hypertension, High Blood Pressure, African American Men
Interventions
Blood Pressure measurement and pharmacy
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
35 Years to 79 Years · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Nov 7, 2026, 2:01 PM EST
Completed Not applicable Interventional Results available

Stress and Hypertension in Dementia Caregivers

NCT05721482
View directory record Official record
Conditions
Hypertension, Stress, Psychological
Interventions
Caregiver Training
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
40 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Nov 7, 2026, 2:01 PM EST
Completed Phase 3 Interventional

Clinical Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Hydrochlorothiazide in Patients With Essential Hypertension.

NCT00219024
View directory record Official record
Conditions
Hypertension
Interventions
aliskiren
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years and older
Enrollment
2,775 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Nov 7, 2026, 2:01 PM EST
Recruiting Not applicable Interventional

Telehealth and Remote Blood Pressure

NCT07356518
View directory record Official record
Conditions
Hypertension, Hypertension in Pregnancy
Interventions
Telehealth visits, In-person visits
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Nov 7, 2026, 2:01 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Collision Warning Device for Blind and Visually Impaired

NCT03057496
View directory record Official record
Conditions
Hemianopia, Hemianopsia, Peripheral Visual Field Defect, Blindness, Retinitis Pigmentosa, Glaucoma
Interventions
Collision warning device
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Nov 7, 2026, 2:01 PM EST
Completed Phase 2 Interventional Results available

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

NCT05737940
View directory record Official record
Conditions
Pulmonary Hypertension (World Health Organization Group 2), Heart Failure
Interventions
AZD3427, Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 130 Years
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
7
States / cities
Beverly Hills, California • La Jolla, California • New Haven, Connecticut + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Nov 7, 2026, 2:01 PM EST
Completed Phase 4 Interventional Results available

Acute Hemodynamic Effects of Sildenafil in Patients With Severe Aortic Stenosis

NCT01060020
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Sildenafil
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Nov 7, 2026, 2:01 PM EST
Completed Not applicable Interventional

Care Transitions for Complex Patient - Cycle 1 and Cycle 2

NCT01039324
View directory record Official record
Conditions
Asthma, Coronary Artery Disease, Diabetes, Hypertension, Congestive Heart Failure
Interventions
Reports, Reports and Notices, Usual care
Other
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
8,422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2014 · Synced Nov 7, 2026, 2:01 PM EST
Not yet recruiting Not applicable Interventional

Enhancing Mental and Physical Health of Women Veterans 3.0

NCT07356479
View directory record Official record
Conditions
Cardiovascular Diseases, Overweight, Obesity, Hypertension, Cholesterol, Diabetes Mellitus, Prediabetic State, Menopause, Cognitive Behavioral Therapy, Primary Health Care, Stress Disorders, Post-Traumatic, Prevention, Implementation Science, Quality Improvement
Interventions
EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Nov 7, 2026, 2:01 PM EST
Completed Phase 4 Interventional Results available

Valsartan Intensified Primary Care Reduction of Blood Pressure Study

NCT00902304
View directory record Official record
Conditions
Hypertension
Interventions
Valsartan and hydrochlorothiazide (HCTZ) - monotherapy, Valsartan and amlodipine, Usual care, Valsartan, Valsartan and hydrochlorothiazide (HCTZ) - combination arm
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
2,337 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Nov 7, 2026, 2:01 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation

NCT00204984
View directory record Official record
Conditions
High Blood Pressure
Interventions
oral hydralazine and intravenous nesiritide
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
65 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 8, 2019 · Synced Nov 7, 2026, 2:01 PM EST
Terminated Phase 4 Interventional Results available

Persistent Postpartum Hypertension Pilot Trial

NCT04349124
View directory record Official record
Conditions
Hypertension in Pregnancy
Interventions
Nifedipine Extended-Release Tablets
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Nov 7, 2026, 2:01 PM EST
Withdrawn Not applicable Interventional

Tailored Drug Titration Through Artificial Intelligence

NCT03397524
View directory record Official record
Conditions
Hypertension
Interventions
optima4BP
Other
Lead sponsor
Optima Integrated Health
Industry
Eligibility
21 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2019 · Synced Nov 7, 2026, 2:01 PM EST
Completed Phase 2 Interventional Results available

Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases

NCT00001723
View directory record Official record
Conditions
Diabetes Mellitus, Hypertension, Metabolic Disease, Obesity, Sleep Apnea Syndrome
Interventions
Orlistat, Placebo
Drug
Lead sponsor
Jack Yanovski
NIH
Eligibility
12 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 18, 2012 · Synced Nov 7, 2026, 2:01 PM EST
Completed Phase 3 Interventional Results available

Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%

NCT03519386
View directory record Official record
Conditions
Glaucoma, Open-Angle, Ocular Hypertension
Interventions
G2-TR intraocular implant containing travoprost, Sham surgery + active-comparator eye drops
Combination Product · Drug
Lead sponsor
Glaukos Corporation
Industry
Eligibility
18 Years and older
Enrollment
590 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Nov 7, 2026, 2:01 PM EST
Withdrawn Phase 2 Interventional

Arginine in Treating Patients With Anti-VEGF Induced Kidney Injury

NCT02882373
View directory record Official record
Conditions
Drug-Induced Nephropathy, Hypertension, Proteinuria
Interventions
Arginine, Placebo
Dietary Supplement · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Nov 7, 2026, 2:01 PM EST
Completed Phase 3 Interventional

Counseling Older Adults to Control Hypertension

NCT01180673
View directory record Official record
Conditions
Hypertension, Vascular Diseases, Cardiovascular Diseases
Interventions
MINT-TLC, Control Condition
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
60 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Nov 7, 2026, 2:01 PM EST
Withdrawn Not applicable Interventional

Utilizing Telemedicine for Hypertension Treatment Lifestyle Modification in Central Harlem

NCT05062473
View directory record Official record
Conditions
Hypertension
Interventions
Lifestyle Modification Webinars Focused on Hypertension Control
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Nov 7, 2026, 2:01 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Blood Pressure in Prehypertensive Older Rural Women Also Known as Wellness for Women: DASHing Toward Health

NCT00580528
View directory record Official record
Conditions
Pre-Hypertension
Interventions
Tailored Internet Newsletters, Tailored print newsletters delivered via mail
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
40 Years to 69 Years · Female only
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Nov 7, 2026, 2:01 PM EST
Completed Phase 2 Interventional Results available

Safety of SonoVue on Pulmonary Hemodynamics

NCT01306292
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
SonoVue, Placebo
Drug
Lead sponsor
Bracco Diagnostics, Inc
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Teaneck, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Nov 7, 2026, 2:01 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Identifying Genes That May Increase the Risk for Heart Disease in African Americans

NCT00344136
View directory record Official record
Conditions
Heart Diseases
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 95 Years
Enrollment
5,302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 29, 2016 · Synced Nov 7, 2026, 2:01 PM EST