- Conditions
- Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy
- Interventions
- Holding, Saliva collection, No Holding
- Behavioral · Other
- Lead sponsor
- MaineHealth
- Other
- Eligibility
- 24 Hours to 2 Days
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Portland, Maine
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 41
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Hypoxic-ischemic Encephalopathy
- Interventions
- Dexmedetomidine
- Drug
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 1 Hour to 1 Day
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Neonatal Encephalopathy, Feeding; Difficult, Newborn
- Interventions
- Osteopathic Manipulative Treatment (OMT)
- Procedure
- Lead sponsor
- MaineHealth
- Other
- Eligibility
- 37 Weeks and older
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Portland, Maine
- Conditions
- Acute Kidney Injury, HIE
- Interventions
- Single Dose Theophylline, Repeat Dose Theophylline
- Drug
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- 1 Hour to 18 Hours
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Hypothermia
- Interventions
- NeoWrap, InfaTherm
- Device
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 24 Weeks to 28 Weeks
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Hypothermia, Neonatal Outcome, Cesarean Section
- Interventions
- Change in ambient operating room temperature
- Other
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- Female only
- Enrollment
- 5,221 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Preterm Less Than 32wks With IVH, WMI/PVL, Late Preterm or Term (37-42wks) With Neonatal Encephalopathy Treated With Hypothermia for HIE
- Interventions
- Prospective Clinical and Neurodevelopmental Data Collection
- Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 31 Weeks to 42 Weeks
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Urea Cycle Disorders, Organic Acidemias
- Interventions
- Therapeutic Hypothermia, Standard of Care Therapy
- Other
- Lead sponsor
- Uta Lichter-Konecki
- Other
- Eligibility
- 1 Day to 30 Days
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2015
- U.S. locations
- 3
- States / cities
- Washington D.C., District of Columbia • New York, New York • Milwaukee, Wisconsin
- Conditions
- Neonatal Encephalopathy
- Interventions
- Enteral Feeding
- Procedure
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 0 Days to 2 Days
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Hypoxic-ischemic Encephalopathy, Neonatal Encephalopathy, Birth Asphyxia
- Interventions
- Erythropoietin, Normal saline
- Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 30 Minutes to 24 Hours
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 7
- States / cities
- Little Rock, Arkansas • Palo Alto, California • San Francisco, California + 4 more
- Conditions
- Neonatal Encephalopathy
- Interventions
- Transcutaneous Carbon Dioxide Monitoring
- Device
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 0 Days to 3 Days
- Enrollment
- 53 participants
- Timeline
- 2019 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain, Encephalopathy, Hypoxic-Ischemic, Hypoxic-Ischemic Encephalopathy, Ischemic-Hypoxic Encephalopathy
- Interventions
- Whole-body Cooling
- Procedure
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 6 Hours
- Enrollment
- 364 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 19
- States / cities
- Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 15 more
- Conditions
- Hypoxic-Ischemic Encephalopathy, Hepatitis B Vaccination, Hypothermia, Newborn
- Interventions
- Hypothermia Protocol
- Other
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 0 Hours to 72 Hours
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Hypothermia, Newborn, Body Temperature Changes, Newborn Thermal Injury
- Interventions
- Weaning incubator (heat) at an lower postnatal weight
- Radiation
- Lead sponsor
- Augusta University
- Other
- Eligibility
- Not listed
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
- Conditions
- Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain, Encephalopathy, Hypoxic-Ischemic, Hypoxic-Ischemic Encephalopathy, Ischemic-Hypoxic Encephalopathy
- Interventions
- Hypothermia, Normothermic Control
- Device · Procedure
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- 33 Weeks to 35 Weeks
- Enrollment
- 168 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2022
- U.S. locations
- 18
- States / cities
- Birmingham, Alabama • Palo Alto, California • Atlanta, Georgia + 14 more
- Conditions
- Hypoxic Ischemic Encephalopathy
- Interventions
- Topiramate, Placebo
- Drug
- Lead sponsor
- Kristin R Hoffman
- Other
- Eligibility
- Up to 6 Hours
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Hypoxic Ischemic Brain Injury, Neonatal Encephalopathy
- Interventions
- Near-Infrared Spectroscopy (NIRS)
- Device
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- Up to 2 Years
- Enrollment
- 125 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2028
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts
- Conditions
- Hyperthermia, Hypothermia
- Interventions
- observational
- Device
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 0 Months to 6 Months
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Hypothermia
- Interventions
- change in temperature
- Other
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- Female only
- Enrollment
- 846 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Infant, Newborn, Hypoxia-Ischemia, Brain
- Interventions
- Induced hypothermia, Control
- Device
- Lead sponsor
- NICHD Neonatal Research Network
- Network
- Eligibility
- Up to 6 Hours
- Enrollment
- 208 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2010
- U.S. locations
- 16
- States / cities
- Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
- Conditions
- Neonatal Hypoxic-Ischemic Encephalopathy (HIE)
- Interventions
- Cool-Cap
- Device
- Lead sponsor
- Olympic Medical
- Industry
- Eligibility
- 1 Hour to 6 Hours
- Enrollment
- 235 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2003
- U.S. locations
- 19
- States / cities
- Little Rock, Arkansas • Oakland, California • San Diego, California + 15 more
- Conditions
- Hypothermia; Anesthesia, Hypothermia, Newborn, Hypothermia, Sequela
- Interventions
- Pre op upper body forced air warming (32˚C), Pre op lower body forced air warming (32˚C), Pre op fluids (45˚C), Intra op upper body forced air warming (32˚C), Intra op fluids at room temperature, Intra op upper body forced air warming at (32˚C), Intra op upper body forced air warming at (42˚C), Intra op lower body forced air warming at (32˚C), Intra op lower body forced air warming at (42˚C), Intra op fluid (42˚C)
- Device
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Anesthesia; Hypothermia, Congenital Heart Disease
- Interventions
- MRI-safe bore covering
- Device
- Lead sponsor
- Andrew Matisoff
- Other
- Eligibility
- Up to 7 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Hypoxic-Ischemic Encephalopathy
- Interventions
- RLS-0071, Placebo
- Drug
- Lead sponsor
- ReAlta Life Sciences, Inc.
- Industry
- Eligibility
- Up to 10 Hours
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 15
- States / cities
- Little Rock, Arkansas • Orange, California • San Diego, California + 11 more