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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:54 PM EDT

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Showing 25–48 of 253 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: ICD Clear all
Completed No phase listed Observational

Risk of Life-threatening Heart Rhythm Disturbances in Siblings

NCT00498524
View directory record Official record
Conditions
Defibrillators, Implantable, Myocardial Infarction, Tachycardias, Ventricular
Interventions
ICD
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2,047 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 7, 2012 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Vaccine Therapy in Treating Patients With Stage IV Breast Cancer

NCT00791037
View directory record Official record
Conditions
HER2-positive Breast Cancer, Male Breast Cancer, Recurrent Breast Cancer, Stage IV Breast Cancer
Interventions
HER-2/neu peptide vaccine, leukapheresis, ex vivo-expanded HER2-specific T cells, cyclophosphamide, sargramostim, laboratory biomarker analysis
Biological · Procedure · Drug + 1 more
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 25, 2017 · Synced Oct 20, 2026, 10:54 PM EDT
Completed No phase listed Observational

Myocardial Injury in Patients With Cardiac Implantable Electronic Devices Undergoing Defibrillation Threshold Testing

NCT04284800
View directory record Official record
Conditions
ICD
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional

The Adjunctive Ventricular Arrhythmia Suppression Trial (AVAST) Pilot

NCT01480336
View directory record Official record
Conditions
Arrhythmia
Interventions
Amiodarone Plus Ranolazine, Amiodarone with Placebo
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
Not listed
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 19, 2013 · Synced Oct 20, 2026, 10:54 PM EDT
Terminated Not applicable Interventional Results available

Comparison of Cyanoacrylate Tissue Adhesive and Suture for Closure of Cardiac Device Pockets

NCT00674128
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Cyanoacrylate tissue adhesive (Dermabond), Polyglactin 910 suture (Vicryl)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 29, 2010 · Synced Oct 20, 2026, 10:54 PM EDT
Recruiting Not applicable Interventional

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

NCT06703489
View directory record Official record
Conditions
Ventricular Tachycardia (VT)
Interventions
Sphere-9 Catheter with the Affera Mapping and Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Boston, Massachusetts • New York, New York • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Serratus Anterior Plane Block Combined With Transversus Thoracic Muscle Plane Block Versus Conventional Local Anesthetic Infiltration for SICD Implantation: A Randomized Controlled Trial

NCT05092490
View directory record Official record
Conditions
Serratus Anterior Plane Block, Transversus Thoracis Plane Block, Subcutaneous ICD
Interventions
Combined serratus anterior plane block and transversus thoracis plane block, Standard local infiltration technique
Procedure
Lead sponsor
New York Presbyterian Brooklyn Methodist Hospital
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 20, 2026, 10:54 PM EDT
Completed No phase listed Observational

Risk Stratification After Acute Myocardial Infarction With Cardiac MRI

NCT03725826
View directory record Official record
Conditions
Acute Myocardial Infarction (AMI)
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Phase 4 Interventional

Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications

NCT00560768
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Ovatio VR 6250 or DR6550
Device
Lead sponsor
LivaNova
Industry
Eligibility
Not listed
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
7
States / cities
Sheffield, Alabama • Tarzana, California • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional

Clinical Investigation of the Medtronic EnTrust™ Implantable Cardioverter Defibrillator (ICD), Model D153ATG

NCT00273195
View directory record Official record
Conditions
Ventricular Arrhythmias
Interventions
Implantable Cardioverter Defibrillator
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
24
States / cities
Little Rock, Arkansas • Glendale, California • Inglewood, California + 21 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2006 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

A Clinical Evaluation of the Durata or Optisure High Voltage Leads and Ellipse VR ICD Undergoing MRI, an IDE Study

NCT02787291
View directory record Official record
Conditions
Implantable Defibrillator User
Interventions
Ellipse VR ICD and Durata/Optisure lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
26
States / cities
Phoenix, Arizona • Bakersfield, California • La Jolla, California + 22 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 20, 2026, 10:54 PM EDT
Not listed No phase listed Observational

Does Lung Impedance Correlate With Changes in BNP in Stable and Acutely Decompensated Heart Failure Patients?

NCT00560339
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Southern New Jersey Cardiac Specialists
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
6
States / cities
Glendale, California • Voorhees Township, New Jersey • Roslyn, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2007 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

Assessment of Primary Prevention Patients Receiving An ICD - Systematic Evaluation of ATP

NCT02923726
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Arm 1 (ATP+Shock), Arm 2 (shock only)
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years and older
Enrollment
2,692 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
89
States / cities
Huntsville, Alabama • Anchorage, Alaska • Mesa, Arizona + 82 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator

NCT02787785
View directory record Official record
Conditions
Tachycardia, Diabetes Mellitus, Cardiovascular Disease
Interventions
Subcutaneous Implantable Cardioverter Defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
36
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Jonesboro, Arkansas + 31 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

Multicenter Automatic Defibrillator Implantation Trial - Reduce Inappropriate Therapy

NCT00947310
View directory record Official record
Conditions
Primary Prevention of Sudden Cardiac Arrest
Interventions
Standard ICD programming, High rate cutoff, Long delay
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional

Postcards to Improve Remote Monitoring Adherence Among Veterans

NCT06068699
View directory record Official record
Conditions
ICD, Pacemaker DDD, Adherence, Patient
Interventions
Postcard
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
6,351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 20, 2026, 10:54 PM EDT
Terminated Not applicable Interventional Results available

DEfibrillators To REduce Risk by MagnetIc ResoNance Imaging Evaluation

NCT00487279
View directory record Official record
Conditions
Coronary Artery Disease, Left Ventricular Dysfunction, Sudden Cardiac Death
Interventions
Defibrillator, Control
Device · Other
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
56
States / cities
Anchorage, Alaska • Tucson, Arizona • Glendale, California + 42 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Phase 1 Interventional

LifeSkills Video Training in Patients About to Receive an Automatic Implantable Cardioverter-Defibrillator (AICD)

NCT01686490
View directory record Official record
Conditions
Focus Whether After Implant Pre-AICD Video Was Helpful
Interventions
Video/workbook for patients about to receive an AICD, LiveSkills Video/Workbook for patients about to receive an AICD
Behavioral
Lead sponsor
Williams LifeSkills
Industry
Eligibility
21 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2012 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

Randomized Study of the Use of Warfarin During Pacemaker or ICD Implantation in Patients Requiring Long Term Anticoagulation

NCT00721136
View directory record Official record
Conditions
Bradycardia, Tachycardia, Atrial Fibrillation, Valvular Heart Disease
Interventions
continue warfarin through the procedure, Hold warfarin, Warfarin held with heparin transition.
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Baltimore, Maryland • Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional Results available

Multicenter Automatic Defibrillator Implantation Trial - Chemotherapy-Induced Cardiomyopathy

NCT02164721
View directory record Official record
Conditions
Cardiomyopathy
Interventions
Three-lead CRT-D (Defibrillator)
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
9
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional

Barriers to Use of Remote Monitoring in Patients With Implantable Cardioverter Defibrillators

NCT02361333
View directory record Official record
Conditions
Cardiac Patients, Implantable Cardioverter Defibrillator
Interventions
Teaching Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 20, 2026, 10:54 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Electronic Patient Notification of Remote ICD Data: Impact of Patient Engagement on Outcomes in the Merlin.Net™

NCT02989090
View directory record Official record
Conditions
Implantable Cardioverter-Defibrillator, Health Information Exchange, Electronic Health Records, Patient Participation
Interventions
Receive Detailed ICD Information-electronic, Receive Detailed ICD Information-paper
Other
Lead sponsor
Parkview Hospital, Indiana
Other
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Oct 20, 2026, 10:54 PM EDT
Active, not recruiting Not applicable Interventional

Assessment of Combined CCM and ICD Device in HFrEF

NCT05855135
View directory record Official record
Conditions
Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation
Interventions
OPTIMIZER® Integra CCM-D System (Treatment Arm)
Device
Lead sponsor
Impulse Dynamics
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
59
States / cities
Glendale, Arizona • Mesa, Arizona • Phoenix, Arizona + 40 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 20, 2026, 10:54 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Fixed Tilt and Tuned Waveforms in Right-sided Implants

NCT00873691
View directory record Official record
Conditions
Healthy
Interventions
ICD
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 20, 2026, 10:54 PM EDT