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ClinicalTrials.gov public records Last synced Oct 14, 2026, 1:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 276 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: ICU Patient Clear all
Not listed No phase listed Observational

Screening Anti-Fungal Exposure in Intensive Care Units

NCT03136926
View directory record Official record
Conditions
Antifungal Agents
Interventions
Not listed
Lead sponsor
The University of Queensland
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 21, 2018 · Synced Oct 14, 2026, 1:38 PM EDT
Not yet recruiting Not applicable Interventional

Sleep Harmonization Via Bundled Team-Based Interventions in the ICU

NCT07840560
View directory record Official record
Conditions
Sleep Deprivation, Critical Illness, Sleep-Wake Disorders, Bundle Care, Implementation Science, Delirium
Interventions
Nighttime noise & light reduction, Clustering patient-care interactions, Non-pharmacologic sleep aids, Daytime light exposure, Encourage out-of-bed activity, Medication management to support nighttime sleep
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
62,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
7
States / cities
La Jolla, California • San Francisco, California • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 14, 2026, 1:38 PM EDT
Terminated No phase listed Observational

Intubated ICU Patients

NCT02171091
View directory record Official record
Conditions
Patients Requiring Endotracheal Intubation
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Oct 14, 2026, 1:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)

NCT07214597
View directory record Official record
Conditions
Postpartum Depression (PPD), Self-Efficacy, Parental Anxiety, Engagement, Patient, Usability, Length of Stay
Interventions
VoiceLove mobile phone application
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 14, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Artificial Intelligence-Generated Written Communication for Families of Intensive Care Unit Patients

NCT06969196
View directory record Official record
Conditions
Communication, ICU
Interventions
Written Communicatoin
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 14, 2026, 1:38 PM EDT
Completed No phase listed Observational

ARC in Hemorrhagic Stroke

NCT02386202
View directory record Official record
Conditions
Hemorrhagic Stroke, Augmented Renal Clearance
Interventions
No intervention
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 14, 2026, 1:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Patient and Caregiver Psychological Functioning Following Neuro-ICU Admission: A Prospective Investigation

NCT02435641
View directory record Official record
Conditions
Intensive Care Neurological Disorder
Interventions
Questionnaires
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 14, 2026, 1:38 PM EDT
Withdrawn Not applicable Interventional

The HEALiX™ Intubated Patient (IP) Pilot Study

NCT04759066
View directory record Official record
Conditions
Device Ineffective, Safety Issues
Interventions
HEALiX
Device
Lead sponsor
Lancaster General Hospital
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Oct 14, 2026, 1:38 PM EDT
Completed Not applicable Interventional Results available

Improving Communication in the PICU: The Navigate Study

NCT02333396
View directory record Official record
Conditions
Communication
Interventions
PICU Supports, Educational Brochure
Other
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Not listed
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 14, 2026, 1:38 PM EDT
Completed Not applicable Interventional Results available

Improving Decision Making for Patients With Prolonged Mechanical Ventilation

NCT01751061
View directory record Official record
Conditions
Surrogate Decision Makers, Prolonged Mechanical Ventilation
Interventions
Decision aid, Usual care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
Chapel Hill, North Carolina • Durham, North Carolina • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Oct 14, 2026, 1:38 PM EDT
Completed Not applicable Interventional

The SOMNUS Study: Sedative Optimization Via Monitoring Neurological Status

NCT00469482
View directory record Official record
Conditions
Delirium, Cognitive Impairment, Critically Ill
Interventions
Sedation,RASS Targeted plus BIS Monitoring, Sedation, RASS Targeted
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 8, 2018 · Synced Oct 14, 2026, 1:38 PM EDT
Completed No phase listed Observational

Sound Levels in the Pediatric Cardiac Critical Care Unit and Their Correlation With Sedation Administration, Delirium Scores and Patient Heart Rate

NCT04777695
View directory record Official record
Conditions
Noise Exposure, Sedative Withdrawal Delirium, Sedative Toxicity
Interventions
Decibel Monitor
Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
Up to 22 Years
Enrollment
64 participants
Timeline
2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 1, 2021 · Synced Oct 14, 2026, 1:38 PM EDT
Completed No phase listed Observational

Pulse Oximetry and Skin Pigmentation - Peds

NCT05185427
View directory record Official record
Conditions
Pulse Oximetry
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Oct 14, 2026, 1:38 PM EDT
Not listed Not applicable Interventional

MANAGE Automated Glucose Monitoring

NCT02211300
View directory record Official record
Conditions
ICU/CCU Patients Requiring Blood Glucose Monitoring
Interventions
The OptiScanner, YSI 2300 STAT Plus™
Device
Lead sponsor
OptiScan Biomedical Corporation
Industry
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
4
States / cities
Boston, Massachusetts • St Louis, Missouri • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2015 · Synced Oct 14, 2026, 1:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients

NCT07649876
View directory record Official record
Conditions
Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients, Agitation Associated With Critical Illness, Anxiety Acute
Interventions
Virtual reality (VR) therapy
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 14, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Positive Suggestions Via MP3 Messages

NCT04437095
View directory record Official record
Conditions
Post Intensive Care Unit Syndrome, Psychological Trauma, Anxiety, Depression, PTSD
Interventions
Psychological Support Based on Positive Suggestion delivered via pre-recorded MP3 message
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 14, 2026, 1:38 PM EDT
Completed Phase 2 Interventional Results available

Anxiety Self-Management for ICU Patients Receiving Mechanical Ventilation

NCT00440700
View directory record Official record
Conditions
Anxiety
Interventions
Anxiety Self-Management, Patient preferred relaxing music, Control 1: Noise-cancelling headphones, Control 2: Standard of Care
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 14, 2026, 1:38 PM EDT
Completed Phase 3 Interventional

ICU Family Communication Study

NCT00720200
View directory record Official record
Conditions
Depression, Depressive Symptoms, Anxiety, Stress Disorders, Post-Traumatic, ICU Hospitalization, Care and Treatment in ICU
Interventions
Facilitator-Based intervention, Usual Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
593 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
2
States / cities
Renton, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Oct 14, 2026, 1:38 PM EDT
Terminated Not applicable Interventional

Early Mobility for the Critically Injured Burn Patient

NCT01866735
View directory record Official record
Conditions
Critically Injured Burn Patients
Interventions
Standardized Rehabilitation Therapy
Other
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
St Louis, Missouri • Chapel Hill, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Oct 14, 2026, 1:38 PM EDT
Not yet recruiting No phase listed Observational

Prospective Observational Multimodal Neuromonitoring in Adult NSICU Patients

NCT07577713
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic, Cerebral Hemorrhage, Ischemic Stroke, Delayed Emergence From Anesthesia, Encephalopathy
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 14, 2026, 1:38 PM EDT
Recruiting Not applicable Interventional

AI-driven Total Parenteral Nutrition Platform

NCT07414576
View directory record Official record
Conditions
Intestinal Failure
Interventions
AI-driven total parenteral nutrition (TPN)
Device
Lead sponsor
Takeoff41, Inc.
Industry
Eligibility
Up to 6 Months
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 14, 2026, 1:38 PM EDT
Active, not recruiting Not applicable Interventional

A Communication Tool to Improve Communication in the ICU

NCT05780918
View directory record Official record
Conditions
Serious Injury, Communication
Interventions
Best Case/Worst Case-ICU Communication Tool
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
7,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Birmingham, Alabama • Davis, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 14, 2026, 1:38 PM EDT
Withdrawn Not applicable Interventional

Improving Muscle Function in Nutritionally at Risk, Elderly Patients

NCT03071354
View directory record Official record
Conditions
Muscle Weakness, ICU-acquired Weakness
Interventions
HMB protein supplement (3g), Nutritional Supplement
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 14, 2026, 1:38 PM EDT
Completed Not applicable Interventional

SHIIFT: Small Tubes to Halt Medical ICU/IMU Frequent Transfusions

NCT05750654
View directory record Official record
Conditions
Anemia
Interventions
Small Phlebotomy Tube Group, Standard Phlebotomy Tube Group
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
688 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 14, 2026, 1:38 PM EDT