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ClinicalTrials.gov public records Last synced Oct 22, 2026, 10:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 276 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: ICU Patients Clear all
Enrolling by invitation Not applicable Interventional

Impact of Intensive Care Unit Nurse Participation in Post - ICU Follow Up Clinic

NCT04243356
View directory record Official record
Conditions
Nurse-Patient Relations, Nurse Role
Interventions
Nurse Encounter Group, Nurse control group
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional Results available

Improving Communication in the PICU: The Navigate Study

NCT02333396
View directory record Official record
Conditions
Communication
Interventions
PICU Supports, Educational Brochure
Other
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Not listed
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 22, 2026, 10:19 AM EDT
Completed No phase listed Observational

Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit

NCT02270502
View directory record Official record
Conditions
Critical Illness, Sarcopenia, Muscle Wasting
Interventions
Ultrasound Philips CX50, Frailty Index Questionnaire, Muscle strength tests
Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 22, 2026, 10:19 AM EDT
Completed Phase 2 Interventional

MENDS Study: Trial in Ventilated ICU Patients Comparing an Alpha2 Agonist Versus a Gamma Aminobutyric Acid (GABA)-Agonist to Determine Delirium Rates, Efficacy of Sedation, Analgesia and Discharge Cognitive Status

NCT00095251
View directory record Official record
Conditions
Delirium
Interventions
Dexmedetomidine, Lorazepam
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 22, 2026, 10:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Patient and Caregiver Psychological Functioning Following Neuro-ICU Admission: A Prospective Investigation

NCT02435641
View directory record Official record
Conditions
Intensive Care Neurological Disorder
Interventions
Questionnaires
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 22, 2026, 10:19 AM EDT
Withdrawn Not applicable Interventional

The HEALiX™ Intubated Patient (IP) Pilot Study

NCT04759066
View directory record Official record
Conditions
Device Ineffective, Safety Issues
Interventions
HEALiX
Device
Lead sponsor
Lancaster General Hospital
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Oct 22, 2026, 10:19 AM EDT
Completed Phase 4 Interventional Results available

Suvorexant and Sleep/Delirium in ICU Patients

NCT04092894
View directory record Official record
Conditions
Insomnia, Sleep Fragmentation, Sleep Initiation and Maintenance Disorders, Postoperative Delirium
Interventions
Suvorexant 20 mg, Placebo oral tablet
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional

Testing a Novel Manual Communication System for Mechanically Ventilated ICU Patients

NCT04105751
View directory record Official record
Conditions
Communication, Ventilation Therapy; Complications
Interventions
Novel Communication System
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Oct 22, 2026, 10:19 AM EDT
Completed No phase listed Observational

ICU Liberation: Does Enhanced Patient Mobilization Improve Outcomes?

NCT03329924
View directory record Official record
Conditions
Early Mobilization of Mechanically Ventilated Patients
Interventions
Activity level measurement by accelerometer
Other
Lead sponsor
Bassett Healthcare
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Cooperstown, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 22, 2026, 10:19 AM EDT
Active, not recruiting Not applicable Interventional Results available

A Communication Tool to Improve Communication in the ICU

NCT05780918
View directory record Official record
Conditions
Serious Injury, Communication
Interventions
Best Case/Worst Case-ICU Communication Tool
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
7,320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Birmingham, Alabama • Davis, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 22, 2026, 10:19 AM EDT
Withdrawn Phase 2 Interventional

Study of BXCL501 In Agitation Associated With Delirium in ICU Patients

NCT05313386
View directory record Official record
Conditions
Agitation, Delirium
Interventions
BXCL501, Placebo film
Drug
Lead sponsor
BioXcel Therapeutics Inc
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 22, 2026, 10:19 AM EDT
Terminated Phase 3 Interventional

Effect of Music on Pain and Anxiety After Surgery

NCT01409044
View directory record Official record
Conditions
Postop Adult ICU Patients
Interventions
Music
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 99 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Oct 22, 2026, 10:19 AM EDT
Terminated Phase 2 Interventional

Pharmacokinetics, Pharmacodynamics and Safety Evaluation of SAR279356 in Intensive Care Unit Mechanically Ventilated Patients

NCT01389700
View directory record Official record
Conditions
Infection Prophylaxis
Interventions
SAR279356, placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
6
States / cities
Los Angeles, California • Stanford, California • Jacksonville, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 22, 2026, 10:19 AM EDT
Not listed No phase listed Observational

Critical Illness Outcomes Study

NCT01109719
View directory record Official record
Conditions
Critical Illness, Intensive Care, Intensive Care Unit
Interventions
Not listed
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
NIH
Eligibility
18 Years and older
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 25, 2010 · Synced Oct 22, 2026, 10:19 AM EDT
Not listed Not applicable Interventional

Systematic Team Approach to Guide Early Mobilization in Surgical Intensive Care Unit Patients

NCT01363102
View directory record Official record
Conditions
Muscle Weakness, Critical Illness, Respiratory Insufficiency
Interventions
SOMS
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
3
States / cities
Boston, Massachusetts • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 22, 2026, 10:19 AM EDT
Terminated Not applicable Interventional Results available

Impact of the Erigo Machine on Functional Recovery in ICU Patients

NCT02615990
View directory record Official record
Conditions
Trauma Patients Requiring Physical Rehabilitation
Interventions
Erigo Pro, Standard Physical Therapy
Device · Other
Lead sponsor
Lisa J. Fryman
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 25, 2018 · Synced Oct 22, 2026, 10:19 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Evaluating Wearable Smart Sensors for Continuous Measurement of Vital Signs in ICU Patients

NCT04723654
View directory record Official record
Conditions
Prematurity
Interventions
Wireless Wearable Vital Sign Monitor
Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Up to 18 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 22, 2026, 10:19 AM EDT
Terminated Phase 2 Interventional Results available

Evaluation of FDY-5301 in Major Trauma Patients in ICU

NCT04430283
View directory record Official record
Conditions
ICU Acquired Weakness
Interventions
FDY-5301, Placebo
Drug · Other
Lead sponsor
Faraday Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
5
States / cities
Torrance, California • Gainesville, Florida • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2023 · Synced Oct 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional

Effect Of Acute Inflammatory Mediators On Functional Limitations In Patients With Acute Respiratory Failure

NCT01707303
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Early ICU rehabilitation strategies, Usual Care
Other
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 22, 2026, 10:19 AM EDT
Completed No phase listed Observational Results available

Feasibility Study to Evaluate Safety and Device Performance of the Hospital Glucose Management System (HGMS)

NCT01763567
View directory record Official record
Conditions
Hyperglycemia
Interventions
Not listed
Lead sponsor
Medtronic MiniMed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 7, 2015 · Synced Oct 22, 2026, 10:19 AM EDT
Active, not recruiting Phase 3 Interventional

A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol

NCT06809218
View directory record Official record
Conditions
Post-Intensive Care Syndrome, Sedation
Interventions
Inhaled isoflurane administered by Sedaconda ACD-S, Intravenous infusion of propofol
Drug
Lead sponsor
Sedana Medical
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 22, 2026, 10:19 AM EDT
Terminated Phase 1 Interventional

How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units

NCT00826553
View directory record Official record
Conditions
Delirium, Respiratory Failure
Interventions
Dexmedetomidine, GABA agonist
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 22, 2026, 10:19 AM EDT
Completed No phase listed Observational

Heparin Antibodies in Intensive Care Unit Patients (HAICU)

NCT00283322
View directory record Official record
Conditions
Heparin-Induced Thrombocytopenia
Interventions
blood samples (2)
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
2
States / cities
Orlando, Florida • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 6, 2007 · Synced Oct 22, 2026, 10:19 AM EDT
Completed Phase 2 Interventional Results available

Anxiety Self-Management for ICU Patients Receiving Mechanical Ventilation

NCT00440700
View directory record Official record
Conditions
Anxiety
Interventions
Anxiety Self-Management, Patient preferred relaxing music, Control 1: Noise-cancelling headphones, Control 2: Standard of Care
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 22, 2026, 10:19 AM EDT