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ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:48 PM EDT

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Showing 49–72 of 1,026 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: INSOMNIA Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Remote Yoga Nidra for Anxiety and Sleep

NCT04571593
View directory record Official record
Conditions
Insomnia Due to Anxiety and Fear
Interventions
Yoga Nidra
Behavioral
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional

Electrophysiologic Changes in Blacks Treated With CBT for Insomnia

NCT02741336
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Self-Monitoring
Behavioral
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional

The Effect of Cognitive Behavioral Therapy for Insomnia on Type 2 Diabetes Health Outcomes

NCT03713996
View directory record Official record
Conditions
Type2 Diabetes, Insomnia
Interventions
Cognitive behavioral therapy for insomnia, Health Education
Behavioral · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
40 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional Results available

Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)

NCT02774642
View directory record Official record
Conditions
Posttraumatic Stress Disorders, Chronic Insomnia
Interventions
CBTI-PE, Hygiene-PE
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 17, 2026, 9:48 PM EDT
Recruiting Phase 3 Interventional

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

NCT06559306
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Seltorexant, Placebo, Selective Serotonin Reuptake Inhibitor (SSRI)/Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 74 Years
Enrollment
752 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
84
States / cities
Birmingham, Alabama • Chandler, Arizona • Tucson, Arizona + 65 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pain Sensitization and Habituation in a Model of Experimentally-induced Insomnia Symptoms

NCT02484742
View directory record Official record
Conditions
Sleep Control Condition, Insomnia Symptoms Induction Condition
Interventions
Insomnia symptom induction
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 45 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 17, 2026, 9:48 PM EDT
Terminated Phase 2 Interventional Results available

The Effects of Suvorexant on Sleep, Stress, and Cue-reactivity in Methamphetamine Use Disorder

NCT05711862
View directory record Official record
Conditions
Methamphetamine Use Disorder
Interventions
suvorexant (SUVO), Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Phase 2 Interventional

Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia Disorder

NCT03056053
View directory record Official record
Conditions
Insomnia Disorder
Interventions
Zolpidem
Drug
Lead sponsor
Idorsia Pharmaceuticals Ltd.
Industry
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
5
States / cities
Santa Monica, California • Atlanta, Georgia • Las Vegas, Nevada + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Consumption of Pep19 on Quality of Life

NCT06359327
View directory record Official record
Conditions
Quality of Life, Obesity, Sleep Quality
Interventions
Placebo, Pep19 2 mg, Pep19 5 mg
Dietary Supplement
Lead sponsor
Proteimax Biotechnology Israel LTD
Industry
Eligibility
40 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Sunrise, Florida
Source: ClinicalTrials.gov public record
Updated Nov 6, 2024 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional

Effects of Insomnia Treatment on Metabolism in Patients With Depression

NCT04719143
View directory record Official record
Conditions
Insomnia Chronic, Insomnia, Insomnia, Primary, Depression, Depressive Symptoms
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Oct 17, 2026, 9:48 PM EDT
Active, not recruiting No phase listed Observational

Impact of GABA Probiotic Lactiplantibacillus Plantarum Lp815 on Sleep Outcomes in Participants with Self-Reported Sleep Disturbance

NCT06789718
View directory record Official record
Conditions
Insomnia (moderate)
Interventions
GABA Probiotic Lactiplantibacillus plantarum Lp815 (5 Billion cfu/dose), Placebo, Optional Sub-Study: Neurotransmitter Urine Test
Dietary Supplement · Other · Diagnostic Test
Lead sponsor
Verb Biotics LLC
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy (CBT) for Nightmares in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans

NCT00691626
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Sleep Disorders, Nightmares
Interventions
CBT for Insomnia plus Imagery Rehearsal, CBT for Insomnia plus psychoeducation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 17, 2026, 9:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurophysiologic Correlates of Hypersomnia

NCT01719315
View directory record Official record
Conditions
Major Depressive Disorder, Primary Hypersomnia, Bipolar Disorder, Narcolepsy, Primary Insomnia
Interventions
Acoustical slow wave induction
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 60 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 24, 2018 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Phase 2 Interventional

A Dose-ranging, Multicenter Polysomnography Trial of PD 0200390 in Adults With Primary Insomnia

NCT00551148
View directory record Official record
Conditions
Primary Insomnia
Interventions
PD 0200390, Placebo
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 64 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
16
States / cities
Glendale, Arizona • Phenoix, Arizona • Phoenix, Arizona + 12 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2012 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Venous Thrombosis Prevention and Sleep Quality: A Comparison of the Kendall and the Recovery Health MAC Systems

NCT06042686
View directory record Official record
Conditions
Deep Venous Thrombosis of Deep Femoral Vein
Interventions
RF Health MAC Device
Device
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
50 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional Results available

Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation

NCT04269239
View directory record Official record
Conditions
Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Healthy Habits, Sleep Habits
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
40 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Galveston, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 17, 2026, 9:48 PM EDT
Recruiting Not applicable Interventional

NiteCAPP: Web-based Interventions for Insomnia in Rural Dementia Caregivers

NCT04896775
View directory record Official record
Conditions
Insomnia, Dementia
Interventions
NiteCAPP CARES, NiteCAPP SHARES
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 17, 2026, 9:48 PM EDT
Completed Not applicable Interventional Results available

MIDAS Cluster Randomized Controlled Trial of Implementation Strategies to Optimize Use of Medications in VA Clinical Settings

NCT05065502
View directory record Official record
Conditions
Polypharmacy, Insomnia, Anticoagulants
Interventions
Academic Detailing (AD), LEAP
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 17, 2026, 9:48 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females

NCT03436745
View directory record Official record
Conditions
Prostatic Neoplasms
Interventions
Zolpidem, ECG
Drug · Diagnostic Test
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 17, 2026, 9:48 PM EDT
Completed No phase listed Observational

To Study the Prevalence of Insomnia in Geriatric COPD Patients Who Are Enrolled in a Pulmonary Rehabilitation Program.

NCT00346554
View directory record Official record
Conditions
COPD, Sleep Disorders
Interventions
Not listed
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Oct 17, 2026, 9:48 PM EDT
Recruiting Not applicable Interventional

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

NCT07385105
View directory record Official record
Conditions
Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
Interventions
Cognitive behavioral Therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 17, 2026, 9:48 PM EDT
Recruiting Not applicable Interventional

Cereset Research Exploratory Study

NCT03777267
View directory record Official record
Conditions
Neurological Diseases or Conditions, Cardiovascular Conditions After Birth, Psychophysiologic Disorders
Interventions
Active CR
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
11 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 17, 2026, 9:48 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Treatment of Comorbid Sleep Disorders and Post Traumatic Stress Disorder (PTSD)

NCT02773693
View directory record Official record
Conditions
Trauma, Insomnia, Nightmares
Interventions
Cognitive Processing Therapy-Cognitive Only (CPT), Cognitive Behavioral Therapy of Insomnia and Nightmares (CBTin), Continuation Cognitive Processing Therapy-Cognitive Only (CPT)
Behavioral
Lead sponsor
University of North Texas, Denton, TX
Other
Eligibility
18 Years to 50 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 17, 2026, 9:48 PM EDT
Terminated Not applicable Interventional

A Pilot Study of Digital Cognitive Behavioral Therapy for Veterans

NCT03688763
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-i)
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 17, 2026, 9:48 PM EDT