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ClinicalTrials.gov public records Last synced Oct 18, 2026, 6:57 AM EDT

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Showing 145–168 of 1,026 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: INSOMNIA Clear all
Completed Not applicable Interventional

Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)

NCT05356364
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia (CBTI), Perinatal Understanding of Mindful Awareness for Sleep (PUMAS)
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Insomnia Treatment and Problems (the iTAP Study)

NCT03627832
View directory record Official record
Conditions
Insomnia, Alcohol; Harmful Use
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep Hygiene
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 30 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Oct 18, 2026, 6:57 AM EDT
Not listed Not applicable Interventional

Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems

NCT02868983
View directory record Official record
Conditions
Arthritis, Asthma, Chronic Obstructive Lung Disease, Diabetes, Heart Failure, Hypertension, Anxiety, Chronic Pain, Depression, Fibromyalgia, Insomnia, Irritable Bowel Syndrome, Problem Drinking, Substance Use Disorder
Interventions
Integration
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
4,025 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Phase 3 Interventional Results available

A Study to Evaluate Next-Dose Transition From Zolpidem to Lemborexant (LEM) for the Treatment of Insomnia

NCT04009577
View directory record Official record
Conditions
Insomnia
Interventions
LEM 5 mg, LEM 10 mg
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
17
States / cities
Glendale, Arizona • Sacramento, California • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Use of an Internet-Based Insomnia Intervention to Prevent Cognitive Decline in Adults With Mild Cognitive Impairment

NCT04382365
View directory record Official record
Conditions
Mild Cognitive Impairment, Cognitive Impairment, Insomnia
Interventions
Sleep Health Using the Internet for Older Adult Sufferers of Insomnia and Sleeplessness
Other
Lead sponsor
University of Virginia
Other
Eligibility
55 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 18, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children

NCT06942455
View directory record Official record
Conditions
Sleep, Sleep Quality, Intervention Study, Ethnic Minority
Interventions
SIESTA, Sleep education and health education control
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Phase 2 Interventional Results available

Insomnia Treatment and EMA (Ecological Momentary Assessment) Outcomes

NCT05908526
View directory record Official record
Conditions
Insomnia
Interventions
Baseline surveys, Cognitive testing and EMAs, Actiwatch, suvorexant (or placebo), Placebo
Behavioral · Device · Drug + 1 more
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 18, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanistic Effect of Walnut Consumption on Sleep Quality

NCT06430086
View directory record Official record
Conditions
Poor Sleep Quality
Interventions
Walnut consumption, HCHS consumption
Other
Lead sponsor
Columbia University
Other
Eligibility
45 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Phase 3 Interventional

Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia.

NCT00671294
View directory record Official record
Conditions
Chronic Insomnia
Interventions
Ramelteon and Placebo (9 possible combinations total)
Drug
Lead sponsor
Takeda
Industry
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
18
States / cities
Hot Springs, Arkansas • Irvine, California • Palm Springs, California + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2012 · Synced Oct 18, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

The Effect of a Custom Pillow on Sleep Quality in Patients With Nonoperative Rotator Cuff Syndrome

NCT05011331
View directory record Official record
Conditions
Rotator Cuff Injuries
Interventions
MedCline Shoulder Relief System
Device
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Zolpidem-MR Administered Over a Long Term Period as Needed for Insomnia (ZOLONG)

NCT00425243
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
zolpidem-MR (SL800750)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years to 64 Years
Enrollment
1,025 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Malvern, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2009 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Tai Chi Chuan on Psychobiological Indicators of Anxiety and Sleep Quality in Young Adults

NCT01624168
View directory record Official record
Conditions
Anxiety
Interventions
Anxiety Management Education, 10 week tai chi intervention, Enhanced tai chi instruction
Behavioral
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 40 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boone, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Phase 1 Interventional

Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep

NCT00127686
View directory record Official record
Conditions
Cough, Respiratory Tract Infections
Interventions
Dextromethorphan, Buckwheat Honey
Drug
Lead sponsor
Penn State University
Other
Eligibility
2 Years to 18 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Adapting CBT-I for Hazardous Alcohol Users

NCT05973955
View directory record Official record
Conditions
Insomnia, Harmful; Use, Alcohol
Interventions
Insomnia Treatment, Education Control
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
25 Years to 64 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of Sleep by WHOOP in Ambulatory Subjects

NCT03692195
View directory record Official record
Conditions
Sleep Quality
Interventions
WHOOP Strap 2.0, No Device
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 45 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Oct 18, 2026, 6:57 AM EDT
Recruiting Phase 2 Interventional

Suvorexant for Treatment of AUD and PTSD

NCT06679062
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD), Insomnia
Interventions
Suvorexant, Placebo
Drug · Other
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
21 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 18, 2026, 6:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Closed Loop TES for Enhancing Slow Wave Sleep

NCT03751982
View directory record Official record
Conditions
Sleep Disturbance, Insomnia
Interventions
Transcranial Electrical Neuromodulation (TES)
Device
Lead sponsor
Brain Electrophysiology Laboratory Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 23, 2018 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Sleep Using Mentored Behavioral and Environmental Restructuring

NCT03327324
View directory record Official record
Conditions
Insomnia
Interventions
Sleep Using Mentored Behavioral and Environmental Restructuring
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health

NCT04001088
View directory record Official record
Conditions
Menopause
Interventions
Probiotic, Placebo
Dietary Supplement · Other
Lead sponsor
Lallemand Health Solutions
Industry
Eligibility
40 Years to 59 Years · Female only
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
5
States / cities
Lake Worth, Florida • Port Saint Lucie, Florida • Atlanta, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Oct 18, 2026, 6:57 AM EDT
Active, not recruiting Early Phase 1 Interventional

Anxiety and Depression Levels in Cancer Patients After Self-Application of EFT (Emotional Freedom Techniques)

NCT00737399
View directory record Official record
Conditions
Depression
Interventions
Lifestyle Counseling with Emotional Freedom Techniques (EFT)
Behavioral
Lead sponsor
Soul Medicine Institute
Other
Eligibility
18 Years to 89 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2028
U.S. locations
1
States / cities
Santa Rosa, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Intranasal Injection of PRP Versus Saline for Treatment of Olfactory Dysfunction

NCT04406584
View directory record Official record
Conditions
Olfactory Disorder, Olfaction Disorders, Olfactory Nerve Injuries, Olfactory Nerve Disorder, Olfactory Nerve Diseases, Covid19, Post-Viral Disorder
Interventions
Injection into olfactory cleft
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
San Diego, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Naturalistic Monitoring and Treatment of Chronic Insomnia

NCT04013321
View directory record Official record
Conditions
Chronic Insomnia
Interventions
SleepScore Max coaching feature, Online CBTi
Device · Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Characteristics of Sleep Patterns in Young Adults With and Without Insomnia

NCT00177216
View directory record Official record
Conditions
Sleep Disorders
Interventions
Zolpidem, Escitalopram, Placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
20 Years to 50 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2016 · Synced Oct 18, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of PeptiSleep on Sleep Quality in Healthy Adults

NCT07258433
View directory record Official record
Conditions
Sleep, Wearable Technology, Cortisol, Healthy Participants, Cognitive Abilities
Interventions
PeptiSleep, Micro-crystalline cellulose
Dietary Supplement
Lead sponsor
Nuritas Ltd
Industry
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 18, 2026, 6:57 AM EDT