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ClinicalTrials.gov public records Last synced Oct 8, 2026, 10:13 AM EDT

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Showing 25–48 of 96 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Idiopathic Scoliosis Clear all
Completed Not applicable Interventional Results available

Scoliosis-Specific Exercises for At-Risk AIS Curves

NCT02807545
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Scoliosis Specific Exercises
Behavioral
Lead sponsor
Texas Scottish Rite Hospital for Children
Other
Eligibility
10 Years to 17 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
6
States / cities
Louisville, Kentucky • Baltimore, Maryland • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 8, 2026, 10:13 AM EDT
Not listed Not applicable Interventional

Ultrasound for Scoliosis Diagnostic Evaluation

NCT03222739
View directory record Official record
Conditions
Scoliosis Idiopathic, Scoliosis; Juvenile
Interventions
Ultrasound
Device
Lead sponsor
Children's National Research Institute
Other
Eligibility
7 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 8, 2026, 10:13 AM EDT
Terminated Phase 4 Interventional Results available

IV Lidocaine in Pediatric AIS

NCT03893318
View directory record Official record
Conditions
Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery
Interventions
IV lidocaine, Placebos
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 8, 2026, 10:13 AM EDT
Withdrawn Phase 3 Interventional

Gabapentin and Chronic Post Surgical Pain

NCT03867240
View directory record Official record
Conditions
Pain, Postoperative, Scoliosis Idiopathic
Interventions
Gabapentin, Placebo
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
10 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Oct 8, 2026, 10:13 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study

NCT07634627
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 17 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2031
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Recruiting Phase 3 Interventional

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

NCT07561827
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Ropivacaine Hydrocloride
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Terminated Not applicable Interventional

Vertebral Body Tethering Treatment for Idiopathic Scoliosis

NCT03802656
View directory record Official record
Conditions
Scoliosis, Spinal Curvatures, Spinal Diseases, Bone Diseases, Musculoskeletal Disease, Adolescent Idiopathic Scoliosis, Juvenile; Scoliosis
Interventions
Anterior Vertebral Body Tethering
Device
Lead sponsor
Ochsner Health System
Other
Eligibility
8 Years to 16 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 8, 2026, 10:13 AM EDT
Completed No phase listed Observational

The Treatment of Progressive Early Onset Spinal Deformities: A Multi-Center Outcome Study

NCT02299362
View directory record Official record
Conditions
Early Onset Scoliosis, Congenital Spinal Deformities, Infantile Idiopathic Scoliosis, Neuromuscular Spinal Deformity, Syndromic Spinal Deformity, Thoracic Insufficiency Syndrome
Interventions
Not listed
Lead sponsor
Growing Spine Study Group
Other
Eligibility
1 Day to 18 Years
Enrollment
2,602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
19
States / cities
Little Rock, Arkansas • Los Angeles, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 8, 2026, 10:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Changes in Cerebral Oxygenation During the Administration of Cell Saver Blood and Allogeneic Blood

NCT02607150
View directory record Official record
Conditions
Idiopathic Scoliosis, Transfusion Reaction
Interventions
Cerebral Oxygenation Changes
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2016 · Synced Oct 8, 2026, 10:13 AM EDT
Completed No phase listed Observational

Development of a Conservative Care and Bracing Registry (CCBR)

NCT07527611
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis, Juvenile Idiopathic Scoliosis, Infantile Idiopathic Scoliosis, Neuromuscular Scoliosis
Interventions
Not listed
Lead sponsor
National Scoliosis Center
Other
Eligibility
1 Year to 18 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Recruiting Not applicable Interventional

Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)

NCT03292601
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
NYRC Brace Scoliosis Monitor
Device
Lead sponsor
Columbia University
Other
Eligibility
8 Years to 17 Years · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Long-Term Outcome Following the Treatment of Pediatric Scoliosis

NCT01760434
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Long-term outcomes
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 99 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 8, 2026, 10:13 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery

NCT06096181
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil, Dexmedetomidine, Posterior Spinal Fusion
Interventions
Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 8, 2026, 10:13 AM EDT
Recruiting Phase 2Phase 3 Interventional

IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

NCT07217873
View directory record Official record
Conditions
Scoliosis Correction, Iron Deficiency, Transfusion Blood, Surgery Complications, Spinal Fusion, Scoliosis Idiopathic Adolescent, Scoliosis Neuromuscular
Interventions
Ferric carboxymaltose IV, Normal Saline (Placebo)
Drug
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 19 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 8, 2026, 10:13 AM EDT
Completed No phase listed Observational Results available

Adolescent Idiopathic Scoliosis (AIS) Patient Positioning in EOS System®

NCT02269657
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
EOS® imaging system
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
10 Years to 18 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myofascial and Articular Treatment of Adolescent Idiopathic Scoliosis

NCT05423509
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent Treatment
Interventions
Dynamic myofascial manipulation, Standard AIS treatment with observation or bracing
Other
Lead sponsor
University of New Mexico
Other
Eligibility
10 Years to 15 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Oct 8, 2026, 10:13 AM EDT
Terminated No phase listed Observational

Robotic vs. Freehand Corrective Surgery for Pediatric Scoliosis

NCT02084264
View directory record Official record
Conditions
Scoliosis
Interventions
Not listed
Lead sponsor
Mazor Robotics
Industry
Eligibility
10 Years to 21 Years
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
San Diego, California • Orlando, Florida • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 8, 2026, 10:13 AM EDT
Terminated Not applicable Interventional Results available

Study of the Braive Growth Modulation System for Progressive Pediatric Scoliosis

NCT04929678
View directory record Official record
Conditions
Juvenile Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Braive™ Growth Modulation System (Braive™ GMS)
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

Virtual Reality After Pediatric Scoliosis Surgery

NCT04584970
View directory record Official record
Conditions
Scoliosis Idiopathic, Pain, Postoperative
Interventions
Applied VR, Apple iPad
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
11 Years to 17 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 16, 2022 · Synced Oct 8, 2026, 10:13 AM EDT
Recruiting Not applicable Interventional

Rethinking Rigidity: Development of a 3D-Printed Scoliosis Brace With Varying Flexibility

NCT06785207
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent Treatment
Interventions
3D-printed scoliosis brace
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 18 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Houston, Texas • The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 8, 2026, 10:13 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Hypertonic Saline in Posterior Spinal Fusion

NCT06822374
View directory record Official record
Conditions
Scoliosis Idiopathic, Scoliosis;Congenital
Interventions
Normosol-R, buffered 2% hypertonic saline
Drug
Lead sponsor
Joseph D. Tobias
Other
Eligibility
10 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional

Spinal Stabilization Exercises for Low Back Pain in Adolescents With Idiopathic Scoliosis

NCT01550497
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Low Back Pain
Interventions
supervised spinal stabilization exercises
Other
Lead sponsor
Texas Scottish Rite Hospital for Children
Other
Eligibility
10 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2021 · Synced Oct 8, 2026, 10:13 AM EDT
Completed Not applicable Interventional Results available

Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients

NCT01549873
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
propofol, Desflurane
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 26, 2015 · Synced Oct 8, 2026, 10:13 AM EDT
Recruiting No phase listed Observational

The Tether™ - Vertebral Body Tethering System Post Approval Study

NCT04505579
View directory record Official record
Conditions
Scoliosis Idiopathic
Interventions
Anterior Vertebral Body Tethering
Device
Lead sponsor
ZimVie
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
10
States / cities
San Diego, California • Aurora, Colorado • Jacksonville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 8, 2026, 10:13 AM EDT