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ClinicalTrials.gov public records Last synced Oct 12, 2026, 3:09 AM EDT

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Showing 73–96 of 97 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Idiopathic Scoliosis Clear all
Recruiting Not applicable Interventional

A Study to Evaluate a New Semi-rigid Brace, the RESILIENT Brace by Thinks Works, as a Way to Limit Curve Worsening in Kids With Idiopathic Scoliosis.

NCT07574632
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
The RESILIENT scoliosis brace system
Device
Lead sponsor
Thinks Works, PBC
Industry
Eligibility
9 Years to 16 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Recruiting Not applicable Interventional

Studying Melatonin and Recovery in Teens

NCT06093477
View directory record Official record
Conditions
Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital, Kyphosis, Spondylolisthesis, Pectus Surgery, Hip Surgery
Interventions
Fast-Dissolve Melatonin Pill, Fast-Dissolve Placebo Pill
Dietary Supplement · Other
Lead sponsor
Stanford University
Other
Eligibility
12 Years to 18 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Not yet recruiting No phase listed Observational

Immune Response to PSF in Idiopathic vs Neuromuscular Scoliosis

NCT07734467
View directory record Official record
Conditions
Posterior Spinal Fusion, Idiopathic Scoliosis, Neuromuscular Scoliosis
Interventions
Serum blood samples for serum biomarkers of immune response
Diagnostic Test
Lead sponsor
Ambrish Patel
Other
Eligibility
0 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Completed Not applicable Interventional Results available

Scoliosis-Specific Exercises for At-Risk AIS Curves

NCT02807545
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Scoliosis Specific Exercises
Behavioral
Lead sponsor
Texas Scottish Rite Hospital for Children
Other
Eligibility
10 Years to 17 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
6
States / cities
Louisville, Kentucky • Baltimore, Maryland • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 12, 2026, 3:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Complementary Therapies in Spinal Fusion Patients

NCT02409615
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Hypnosis Therapy, Healing Touch Therapy
Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 12, 2026, 3:09 AM EDT
Completed Not applicable Interventional

Anesthetic Optimization in Scoliosis Surgery

NCT02481570
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Respiratory Depression, Postoperative Pain
Interventions
pharmacokinetic simulation
Other
Lead sponsor
University of Florida
Other
Eligibility
10 Years to 18 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 12, 2026, 3:09 AM EDT
Withdrawn Phase 3 Interventional

Gabapentin and Chronic Post Surgical Pain

NCT03867240
View directory record Official record
Conditions
Pain, Postoperative, Scoliosis Idiopathic
Interventions
Gabapentin, Placebo
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
10 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Oct 12, 2026, 3:09 AM EDT
Not listed No phase listed Observational

Adolescent Idiopathic Scoliosis Outcomes Database Registry

NCT01661959
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
Setting Scoliosis Straight Foundation
Other
Eligibility
10 Years to 21 Years
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2025
U.S. locations
12
States / cities
San Diego, California • Wilmington, Delaware • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 12, 2026, 3:09 AM EDT
Enrolling by invitation Phase 2 Interventional Accepts healthy volunteers

Low Dose Dexmedetomidine as a Postoperative Pain Adjunct

NCT06067893
View directory record Official record
Conditions
Spinal Fusion, Adolescent Idiopathic Scoliosis
Interventions
Dexmedetomidine, Normal Saline
Drug
Lead sponsor
Nichole Doyle
Other
Eligibility
10 Years to 21 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Kids With Iron Deficiency and Scoliosis

NCT06042699
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis, Perioperative/Postoperative Complications, Iron Deficiencies, Anemia, Spinal Fusion, Postoperative Cognitive Dysfunction
Interventions
Oral ferrous sulfate, Oral placebo tablet
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 26 Years
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Terminated Not applicable Interventional Results available

Safety Outcomes of Vertebral Body Tethering Technique

NCT04119284
View directory record Official record
Conditions
Idiopathic Adolescent Scoliosis
Interventions
Anterior body tether (ABT)
Device
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
8 Years to 16 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 12, 2026, 3:09 AM EDT
Completed No phase listed Observational

Return to Sport After Posterior Spinal Fusion

NCT03513120
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Posterior Spinal Fusion
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 19, 2020 · Synced Oct 12, 2026, 3:09 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Yoga for Juvenile Idiopathic Scoliosis

NCT07818148
View directory record Official record
Conditions
Juvenile Idiopathic Lumbar Scoliosis
Interventions
Therapeutic yoga pose, Sham yoga pose
Behavioral
Lead sponsor
Manhattan Physical Medicine and Rehabilitation, LLP
Other
Eligibility
8 Years to 12 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Completed Phase 4 Interventional Results available

Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis

NCT02651324
View directory record Official record
Conditions
Idiopathic Scoliosis, Post-operative Pain
Interventions
Ketamine, Placebo
Drug · Other
Lead sponsor
Albany Medical College
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2025 · Synced Oct 12, 2026, 3:09 AM EDT
Completed Not applicable Interventional Results available

Virtual Reality After Pediatric Scoliosis Surgery

NCT04584970
View directory record Official record
Conditions
Scoliosis Idiopathic, Pain, Postoperative
Interventions
Applied VR, Apple iPad
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
11 Years to 17 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 16, 2022 · Synced Oct 12, 2026, 3:09 AM EDT
Recruiting Phase 3 Interventional

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

NCT07561827
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Ropivacaine Hydrocloride
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study

NCT07634627
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 17 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2031
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Terminated Not applicable Interventional

Complex Spine Enhanced Recovery After Surgery (ERAS)

NCT04538092
View directory record Official record
Conditions
Scoliosis Idiopathic
Interventions
Enhanced Recovery After Surgery Protocol
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 12, 2026, 3:09 AM EDT
Recruiting Not applicable Interventional

A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

NCT04914507
View directory record Official record
Conditions
Scoliosis Idiopathic
Interventions
Anterior Vertebral Body Tethering
Device
Lead sponsor
Pediatric Spine Foundation
Other
Eligibility
Up to 18 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
11
States / cities
Washington D.C., District of Columbia • Chicago, Illinois • Saint Paul, Minnesota + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Active, not recruiting Not applicable Interventional

Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery

NCT04031716
View directory record Official record
Conditions
Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
Interventions
Meditation
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery

NCT06096181
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil, Dexmedetomidine, Posterior Spinal Fusion
Interventions
Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 12, 2026, 3:09 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

NCT05071144
View directory record Official record
Conditions
Spine Deformity, Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis, Spondylolisthesis, Congenital Scoliosis, Neuromuscular Scoliosis
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Years to 21 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2031
U.S. locations
10
States / cities
Los Angeles, California • Aurora, Colorado • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 12, 2026, 3:09 AM EDT
Terminated Not applicable Interventional Results available

Single vs Double Epidural Catheter Analgesia for Scoliosis Surgery

NCT01900626
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
epidural catheter
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
11 Years to 18 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Oct 12, 2026, 3:09 AM EDT
Recruiting No phase listed Observational

The BRIDGE Pain Study

NCT07602595
View directory record Official record
Conditions
Juvenile Idiopathic Arthritis (JIA), Fibromyalgia, Lupus, Scoliosis, Pectus Excavatum, Chronic Pain, Musculoskeletal Pain
Interventions
Not applicable- observational study
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
14 Years to 26 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 12, 2026, 3:09 AM EDT