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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

The Effect of Higher Protein Dosing in Critically Ill Patients

NCT03160547
View directory record Official record
Conditions
Critical Illness, Malnutrition
Interventions
Usual Protein/Amino Acid Group, Higher Protein/Amino Acid Group
Other
Lead sponsor
Clinical Evaluation Research Unit at Kingston General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
21
States / cities
Phoenix, Arizona • Long Beach, California • Evanston, Illinois + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2022 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Results available

Restore Resilience in Critically Ill Children

NCT04695392
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome
Interventions
R2 Bundle
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
6 Months to 17 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Results available

PPV to Guide Fluid Management in the PICU

NCT02308371
View directory record Official record
Conditions
Sepsis, Systemic Inflammatory Response Syndrome
Interventions
Automated Pulse Pressure Variation
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Up to 17 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 1, 2017 · Synced Jun 27, 2026, 1:08 PM EDT
Active, not recruiting No phase listed Observational

Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study

NCT04967365
View directory record Official record
Conditions
Critical Illness, Post Intensive Care Unit Syndrome
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
1 Month to 16 Years
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
30
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 26 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 27, 2026, 1:08 PM EDT
Not listed No phase listed Observational

Study of Ceftazidime-Avibactam Blood Concentrations in Intensive Care Unit Patients With Renal Failure Requiring Continuous Dialysis

NCT03243864
View directory record Official record
Conditions
Renal Failure, Bacterial Infections, Critical Illness
Interventions
Ceftazidime-avibactam
Drug
Lead sponsor
Temple University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Jun 27, 2026, 1:08 PM EDT
Not listed Not applicable Interventional

Non-invasive Fluid Management

NCT02892799
View directory record Official record
Conditions
Respiratory Distress Syndrome, Adult
Interventions
NICOM-Guided Diuresis, Standard of Care
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Apr 7, 2019 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional

Noninvasive Assessment of Tissue Perfusion Status in Critically Ill Pediatric Patients

NCT01760044
View directory record Official record
Conditions
Sepsis, Shock
Interventions
Tissue oxygenation monitoring
Device
Lead sponsor
University of Michigan
Other
Eligibility
30 Days to 18 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Jun 27, 2026, 1:08 PM EDT
Completed No phase listed Observational

Study of Intracranial Pressure (ICP) Monitoring in Critically Ill

NCT01330264
View directory record Official record
Conditions
Intracranial Pressure
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2012 · Synced Jun 27, 2026, 1:08 PM EDT
Withdrawn Not applicable Interventional

Influence of Mechanical Ventilation Mode on Arterial Pressure Variations- a Pilot Study

NCT03246425
View directory record Official record
Conditions
Blood Pressure, Critical Illness, Hypovolemia
Interventions
Ventilator mode change, Monitoring of blood pressure variation
Other · Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Phase 1 Interventional Results available

Imipenem/Cilastatin/Relebactam PK in ECMO

NCT04493151
View directory record Official record
Conditions
Sepsis
Interventions
Imipenem, Cilastatin and Relebactam
Drug
Lead sponsor
Joseph L. Kuti, PharmD
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Results available

Multi-center Evaluation of the NEMO Gauge to Aid in Correct Positioning of the Endotracheal Tube

NCT02787681
View directory record Official record
Conditions
Respiratory Failure
Interventions
NEMO Gauge
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Loma Linda, California • Moreno Valley, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2020 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Phase 4 Interventional Results available

Prandial Insulin Dosing in Hospitalized Patients

NCT01101867
View directory record Official record
Conditions
Diabetes, Admitting Hospital, Non-critically Ill
Interventions
Aspart fixed dose, Aspart flexible dose
Drug
Lead sponsor
Kathleen Dungan
Other
Eligibility
18 Years to 80 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional

ECG Leadwires: Disposable Versus Cleaned, Reusable

NCT01411553
View directory record Official record
Conditions
Critically Ill Patients, Cardiovascular Surgery Telemetry Patients
Interventions
Disposable ECG-LW
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
4,056 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Hypovitaminosis D in Neurocritical Patients

NCT02881957
View directory record Official record
Conditions
Craniocerebral Trauma, Intracranial Aneurysm, Brain Neoplasms, Spinal Cord Injuries, Seizures, Meningitis, Stroke, Intracranial Hemorrhages, Critical Illness, Vitamin d Deficiency
Interventions
Cholecalciferol, Placebo
Drug · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional

Patient Engagement Initiative

NCT02721810
View directory record Official record
Conditions
Critical Illness
Interventions
Consideration of 3-month functional prognosis
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
25 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional

Move to Music Video Intervention for ICU Survivors

NCT04977297
View directory record Official record
Conditions
Critical Illness, Intensive Care Unit Syndrome
Interventions
Move to Music Intervention (M2M), Move to Music -Video (M2M-V) Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Community Considerations, Opinions, Values, Impacts, and Decisions for COVID-19

NCT04373135
View directory record Official record
Conditions
Covid-19, Critical Illness, Attitude of Health Personnel, Attitude to Health, Health Behavior, Health Care Utilization
Interventions
Brief educational video
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
1,971 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional

The Clinical Informationist: Does the Model Work

NCT00226291
View directory record Official record
Conditions
Critical Illness
Interventions
Synthesized evidence report
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
Not listed
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 27, 2014 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional

Intraosseous Catheter Confirmation Study

NCT03908879
View directory record Official record
Conditions
Critical Illness
Interventions
Standard intraosseous (IO) catheter confirmation procedure, Color flow Doppler intraosseous (IO) catheter confirmation procedure, Pressure transduction intraosseous (IO) catheter confirmation procedure
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Jun 27, 2026, 1:08 PM EDT
Completed No phase listed Observational

Acute Kidney Injury in Critically Ill Patients

NCT02765464
View directory record Official record
Conditions
Acute Renal Injury
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Family Preparation Study For Withdrawal of Mechanical Ventilation From Their Family Member

NCT00214344
View directory record Official record
Conditions
Mechanical Ventilation, Critically Ill
Interventions
family preparation for withdrawing life support
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 4, 2015 · Synced Jun 27, 2026, 1:08 PM EDT
Recruiting Phase 1Phase 2 Interventional

Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial

NCT07220733
View directory record Official record
Conditions
Critical Illness, Post Operative Complication, Thoracic Surgery
Interventions
Self-balancing robotic exoskeleton (Atalante X)
Device
Lead sponsor
Wandercraft
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Jun 27, 2026, 1:08 PM EDT
Terminated Phase 4 Interventional Results available

Anticoagulation in Critically Ill Patients With COVID-19 (The IMPACT Trial)

NCT04406389
View directory record Official record
Conditions
COVID-19
Interventions
Enoxaparin sodium, Unfractionated heparin, Fondapariniux, Argatroban
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Jun 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Results available

Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients

NCT00133978
View directory record Official record
Conditions
Critical Illness, Sepsis, Multiple Organ Failure
Interventions
Glutamine, Antioxidants, Glutamine + Antioxidants, Placebo
Other
Lead sponsor
Daren K. Heyland
Other
Eligibility
18 Years and older
Enrollment
1,223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
5
States / cities
Aurora, Colorado • Louisville, Kentucky • Dayton, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Jun 27, 2026, 1:08 PM EDT