Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 5, 2026, 3:29 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1849–1872 of 1,885 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Impaired Cognition Clear all

Conditions: Stroke, Stroke Sequelae, Cognitive Impairment
Interventions: Anodal transcranial Direct Current Stimulation (A-tDCS), Sham Intervention; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Amnestic Mild Cognitive Impairment
Interventions: mSIM intervention plus activity monitoring, Activity monitoring; Behavioral
Lead sponsor: Jennifer Bramen; Other
Eligibility: 50 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Mild Cognitive Impairment
Interventions: Rosiglitazone; Drug
Lead sponsor: University of Washington; Other
Eligibility: 55 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 3
States / cities: Phoenix, Arizona • Los Angeles, California • Seattle/Tacoma, Washington

Conditions: Dementia, Cognition Disorders, Cerebral Ischemic Events
Interventions: Dabigatran Etexilate, Warfarin; Drug
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 65 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Murray, Utah

Conditions: Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Cognition, Microvascular Function, Gut Microbiota, Endothelial Function (Reactive Hyperemia), Arterial Stiffness, Blood Pressure, Adult
Interventions: Peanuts; Dietary Supplement
Lead sponsor: Georgia State University; Other
Eligibility: 20 Years to 59 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Parkinson Disease, Mild Cognitive Impairment, Old Age; Dementia
Interventions: Adaptango Performance Process (APP) program; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Alcohol Use Disorder, PTSD, Cognitive Dysfunction
Interventions: Cognitive Training, Cognitive training placebo control; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Memory Impairment Due to Corticosteroid Use, Hypomania Due to Corticosteroid Use, Hippocampal Atrophy Due to Corticosteroid
Interventions: Lamotrigine (Drug); Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 28 participants
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Healthy
Interventions: NeuroQ; Dietary Supplement
Lead sponsor: LifeSeasons Inc.; Industry
Eligibility: 45 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Studio City, California • Flower Mound, Texas

Conditions: Alzheimer Disease, Mild Cognitive Impairment
Interventions: All Subjects; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 50 Years to 85 Years
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Obesity, Vascular Dementia, Cognitive Impairment
Interventions: Urolithin A, Placebo; Dietary Supplement · Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 40 Years to 64 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: MCI, Mild Cognitive Impairment, Mild Cognitive Impairment (MCI)
Interventions: Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT-MCI), Brief Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (bME-CCT-MCI); Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 84 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Schizophrenia Spectrum and Other Psychotic Disorders, Cognitive Impairment
Interventions: rTMS, Computerized cognitive training; Device · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Cognitive Dysfunction
Interventions: iomazenil; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 45 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2018
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Alzheimer Disease, Cognitive Decline, Aging
Interventions: California Cognitive Assessment Battery; Diagnostic Test
Lead sponsor: Neurobehavioral Systems, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Berkeley, California

Conditions: Mild Cognitive Impairment, Age-related Cognitive Decline
Interventions: Music Training I; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 60 Years and older
Enrollment: 268 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Alzheimer Disease
Interventions: Empagliflozin, Insulin, Insulin Placebo, Empagliflozin Placebo; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 55 Years to 85 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Alzheimer Disease
Interventions: LY3439539; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 50 Years to 85 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 9
States / cities: Irvine, California • Long Beach, California • Los Angeles, California + 5 more

Conditions: Cognitive Impairment, Carotid Artery Plaque, Inflammation
Interventions: Imaging with flutemetamol F 18 PET/CT; Drug
Lead sponsor: Scott Mcnally; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2030
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Illness, Critical, Anxiety, Depression, Post Traumatic Stress Disorder, Cognitive Impairment
Interventions: positive suggestion; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Mild Cognitive Impairment (MCI), Cognition, Brain Aging, Microbiome Dysbiosis, Leaky Gut Syndrome, Gut Inflammation, Inflammaging
Interventions: LpD3.5, Placebo; Dietary Supplement
Lead sponsor: University of South Florida; Other
Eligibility: 60 Years and older
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Mild Cognitive Impairment, Mild Dementia, Moderate Dementia, Alzheimer Disease
Interventions: Biological/Vaccine: Bacillus Calmette-Guerin (BCG); Biological
Lead sponsor: Steven E Arnold, MD; Other
Eligibility: 55 Years to 85 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Breast Cancer, Locally Advanced Breast Cancer, Cognitive Impairment, Cognitive Decline, Cognitive Change, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III
Interventions: Memantine, Placebo medication, Exercise Intervention, Exercise Control; Drug · Other
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Agitation Associated With Alzheimer's Disease, Alzheimer's Type, Mental Disorder, Nervous System Diseases
Interventions: Not listed
Lead sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.; Industry
Eligibility: Not listed
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 28
States / cities: Tuscaloosa, Alabama • Costa Mesa, California • Lakewood, California + 21 more

Search by objective public record fields.

TDCS to Improve Post-Stroke Cognitive Impairment

mSIM: Mobile Simultaneous Aerobic Exercise and Memory Training Intervention for Amnestic Mild Cognitive Impairment

Rosiglitazone Effects on Cognition for Adults in Later Life

Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation

Peanuts for Cardiometabolic, Brain, and Intestinal Health

Adaptango Performance PRocess for Older Adults Community reHabilitation

Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder

Clinical Trial of Lamotrigine to Reverse Cognitive Impairment in Chronic Corticosteroid-Treated Patients

A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline

A Longitudinal Evaluation of a Radiotracer for Use in Tau Tracking

Urolithin A Supplementation in Middle-aged Adults With Obesity

Telehealth-Adapted Compensatory Training and Intervention for Cognition

Repetitive TMS & Cognitive Training in Adults With Schizophrenia

GABA-glutamate Interactions and Psychosis

Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease

Interventions to Attenuate Cognitive Decline: Keys to Staying Sharp

Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease

A Study of LY3439539 in Participants With Alzheimer's Disease

The Role of Large Artery Plaque Imaging Features in Predicting Inflammation and Cognition

ICU Doulas Providing Psychological Support

LpD3.5 Intervention Study in Older Adults- LISA-I Trial

A Trial to Evaluate the Effects of BCG in Adults With MCI and Mild-to-Moderate AD

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

Safety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previously Participated in a Double-blind Trial of Brexpiprazole or Placebo