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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Impaired Driving Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Interactive Text-Message Based Brief Intervention to Reduce Substance-Impaired Driving Among College Students

NCT03496129
View directory record Official record
Conditions
Alcohol-Impaired Driving
Interventions
Personalized feedback, Personalized feedback and text messages, Information Only
Behavioral
Lead sponsor
Western Kentucky University
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Bowling Green, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alcohol Impaired Driving: From the Laboratory to the Natural Environment

NCT03846050
View directory record Official record
Conditions
Drinking and Driving
Interventions
BAC feedback/warning, No BAC feedback/warning
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 35 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Jul 20, 2026, 6:40 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Use of Driving Tests to Evaluate Patient Performance on Oral Opioids

NCT00659035
View directory record Official record
Conditions
Chronic Pain
Interventions
Not listed
Lead sponsor
Asokumar Buvanendran
Other
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Effects of Cannabidiol on the Driving Ability of Healthy Adults

NCT04590495
View directory record Official record
Conditions
Driving Performance, Cognitive Impairment, Sedation Complication, Mood
Interventions
300 mg Cannabidiol (CBD) oil, Placebo
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Phase 4 Interventional Results available

Vivitrol for Reducing Driving While Impaired Behavior Among Repeat Offenders

NCT00537745
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Vivitrol (Medication Therapy), Medication Management Therapy
Drug · Other
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 26, 2012 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Phase 2 Interventional

Evaluation of an School-based Alcohol Prevention Program for Middle School Students

NCT01847183
View directory record Official record
Conditions
Alcohol-related Disorders, Drinking and Driving, Neurological Impairment
Interventions
Click City®: Alcohol
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
12 Years to 16 Years
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project MADD - NIH Underage DUI and Ride

NCT03506880
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen
Interventions
MADD Materials, Surgeon General Materials
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Jul 20, 2026, 6:40 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Neuroscience of Alcohol and Marijuana Impaired Driving

NCT03431987
View directory record Official record
Conditions
Marijuana Usage, Alcohol Drinking
Interventions
One day with a dose of placebo cannabis paired with alcohol, One day with a dose of active THC cannabis paired with alcohol
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
21 Years to 40 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders

NCT04587609
View directory record Official record
Conditions
Distracted Driving, Driving Impaired
Interventions
Free Phone Mounts, Commitment Contract, Personalized Habit Tips, Social Gamification Feedback, "Contest" Financial Incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,668 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving

NCT00559819
View directory record Official record
Conditions
Driving, Intoxication, Impairment, Alcohol Impaired Driving
Interventions
placebo, Alcohol
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Impaired Driving in the Natural Environment

NCT03503396
View directory record Official record
Conditions
Driving Under the Influence
Interventions
BAC Driving Feedback/Warning, No Feedback
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

High Confusion: Cannabis & Driving

NCT06236815
View directory record Official record
Conditions
Impairment, Cognitive, Impairment of Attention, Impairment, Psychomotor
Interventions
Delta-9-THC, Delta-8-THC, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 49 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans

NCT01590277
View directory record Official record
Conditions
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil, Alcohol Effect, Driving Under the Influence, Alcohol Impairment
Interventions
Active Ethanol, Active Iomazenil, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 35 Years · Male only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Jul 20, 2026, 6:40 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Evaluation of an Interactive Mobile Phone-Based Brief Intervention to Reduce Substance-Impaired Driving

NCT05537116
View directory record Official record
Conditions
Driving Impaired
Interventions
Personalized feedback, Personalized feedback and text messages, Information Only
Behavioral
Lead sponsor
Western Kentucky University
Other
Eligibility
18 Years to 29 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Bowling Green, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cannabis Impairment Detection Application (CIDA)

NCT04230460
View directory record Official record
Conditions
Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
Interventions
Cannabis (THC) (Inhaled) Placebo, Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
Drug
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Jul 20, 2026, 6:40 PM EDT
Recruiting Not applicable Interventional

User-friendliness of a Portable Driving Simulator

NCT03969927
View directory record Official record
Conditions
Parkinson Disease, Multiple Sclerosis, Stroke
Interventions
Low-Fidelity PDS, High Fidelity Fixed-Base Simulator
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
25 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Phenytoin and Driving Safety: A Randomized, Controlled Cross-Over Study

NCT00581893
View directory record Official record
Conditions
Cognitive Measures, Driving Simulator Performance
Interventions
Phenytoin, Placebo oral capsule
Drug
Lead sponsor
University of Iowa
Other
Eligibility
25 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Jul 20, 2026, 6:40 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Detection of Cannabis Impairment With ISBRG's SpotLight-THC

NCT05276232
View directory record Official record
Conditions
Cannabis
Interventions
Cannabis(THC) inhaled
Drug
Lead sponsor
ISBRG Corp
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fire Fighter Fatigue Management Program: Operation Healthy Sleep

NCT01988129
View directory record Official record
Conditions
Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea, Impaired Driving, Injuries
Interventions
Sleep disorders education and screening
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Jul 20, 2026, 6:40 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents

NCT04564599
View directory record Official record
Conditions
Ride Sharing, Alcohol Drinking, Alcohol Intoxication, Drug Use, Motor Collision, Sexual Assault
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging Transdermal Alcohol Monitoring to Reduce Drinking Among DWI Defendants

NCT03638596
View directory record Official record
Conditions
Drunk Driving
Interventions
Contingency Management, Control
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance

NCT06218550
View directory record Official record
Conditions
Cannabis
Interventions
Delta-9-THC, Delta-8-THC, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 20, 2026, 6:40 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

The Impact and Detection of Driving Impairments Associated With Acute Cannabis Smoking

NCT02849587
View directory record Official record
Conditions
Cannabis Intoxication
Interventions
Cannabis
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Jul 20, 2026, 6:40 PM EDT