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ClinicalTrials.gov public records Last synced Oct 6, 2026, 6:55 PM EDT

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Showing 121–144 of 692 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Impaired Glucose Tolerance Clear all
Active, not recruiting Not applicable Interventional Results available

Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components

NCT05318183
View directory record Official record
Conditions
PreDiabetes, Dysbiosis, Endotoxemia, Inflammation
Interventions
Whole Wheat Bread, White Bread (control)
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Results available

The Fasting II Study

NCT01792986
View directory record Official record
Conditions
Diabetes, Metabolic Diseases
Interventions
water-only 24-hour fasting once per week for 6 weeks
Behavioral
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
30 Years to 69 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Phase 2 Interventional

The Effects of Apple Consumption on Cardiovascular Health in Prediabetics and Type 2 Diabetics

NCT02224365
View directory record Official record
Conditions
Diabetes, Cardiovascular Diseases, Prediabetes
Interventions
Apple, Placebo
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional

Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes

NCT02896010
View directory record Official record
Conditions
Prediabetes, Hyperglycemia, Postprandial Hyperglycemia, Impaired Glucose Tolerance, Impaired Fasting Glucose
Interventions
Sweetch App + DBWS, Sweetch App Alone
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Baltimore, Maryland • Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 27, 2018 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

ForgIng New Paths to Prevent DIabeTes (FINDIT)

NCT02747108
View directory record Official record
Conditions
Prediabetes
Interventions
Blood Test Group Intervention, Brochure Group Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
315 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 6, 2026, 6:55 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Vascular Function, Endothelin, and Inflammation in Pre-diabetic Obesity Versus Lean Healthy Controls

NCT00837590
View directory record Official record
Conditions
Pre-diabetes, Obesity
Interventions
Chronic salsalate, Acute Salsalate
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 6, 2026, 6:55 PM EDT
Completed No phase listed Observational

Gender Differences in Prevalence of Undiagnosed Diabetes in ACS

NCT00589459
View directory record Official record
Conditions
Pre-diabetes, Diabetes
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
30 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
2
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Twins Nutrition Study (TwiNS): Vegan vs. Omnivore

NCT05297825
View directory record Official record
Conditions
Lipid Metabolism, Glucose Intolerance, Weight Change, Body, Microbiome, Inflammation, Immune Function
Interventions
Vegan diet, Omnivore diet
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2024 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes

NCT03500640
View directory record Official record
Conditions
Obesity, PreDiabetes, Aging
Interventions
DPP Intensive: 30-minute calls, DPP Support: 15-minute calls
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Daily Vinegar Ingestion and 24-Hour Blood Glucose Control

NCT06319443
View directory record Official record
Conditions
Glucose Intolerance
Interventions
Liquid vinegar, vinegar pill
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Phase 4 Interventional Results available

Metabolic Effects of Antihypertensive Drugs on People With Metabolic Syndrome (The MEAD Study)

NCT00887510
View directory record Official record
Conditions
Hypertension
Interventions
Hydrochlorothiazide, Trandolapril
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2014 · Synced Oct 6, 2026, 6:55 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

The Significance of Glucose Intolerance in the Pathogenesis of Idiopathic Axonal Polyneuropathy

NCT00228345
View directory record Official record
Conditions
Idiopathic Axonal Polyneuropathy, Abnormal OGTT
Interventions
Optical coherence tomography,Fluorescein angiography
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
50 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Diets Containing Beef vs. Poultry on Pancreatic Beta-Cell Function

NCT05456477
View directory record Official record
Conditions
PreDiabetes
Interventions
Beef, Poultry
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diabetes Risk Education and Communication Trial

NCT03283657
View directory record Official record
Conditions
PreDiabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, Body Weight, Body Weight Changes
Interventions
DiRECT, Usual care (UC)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Walnuts to Achieve Lasting NUTrition to Prevent Diabetes

NCT03334175
View directory record Official record
Conditions
PreDiabetes, Overweight and Obesity
Interventions
Walnuts
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Phase 1Phase 2 Interventional

Use of a Nutritional Supplement to Treat Diabetic Symptoms in HIV-Infected Adults

NCT00109746
View directory record Official record
Conditions
Insulin Resistance, HIV Infections
Interventions
chromium picolinate
Dietary Supplement
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2016 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional

Does Flaxseed Supplementation Improve Glycemic Control in Individuals With Pre-diabetes?

NCT01698112
View directory record Official record
Conditions
PreDiabetes
Interventions
Flaxseed High Dose, Flaxseed Low Dose
Dietary Supplement
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
50 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Colorado Springs, Colorado • Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Oct 2, 2012 · Synced Oct 6, 2026, 6:55 PM EDT
Recruiting Phase 4 Interventional

Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes

NCT05119179
View directory record Official record
Conditions
PreDiabetes
Interventions
Semaglutide
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Brownsville, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional

Heat Therapy and Cardiometabolic Health in Obese Women

NCT03644524
View directory record Official record
Conditions
Obesity, Polycystic Ovary Syndrome, Prehypertension, PreDiabetes, Cardiovascular Risk Factor, Metabolic Syndrome
Interventions
Heat therapy
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Oct 6, 2026, 6:55 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Microlearning Application for Diabetes Prevention

NCT05071820
View directory record Official record
Conditions
PreDiabetes, Elevated Blood Sugar
Interventions
Health U mobile application, National Diabetes Prevention Program
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional

Undiagnosed Diabetes in a Dental Setting

NCT01711385
View directory record Official record
Conditions
Prediabetic State, Type 2 Diabetes Mellitus With Oral Complications, Periodontal Pocket, Tooth Loss
Interventions
Enhanced intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
30 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Identification of Muscle-specific Biomarkers of Fatty Acid Beta-oxidation

NCT01494025
View directory record Official record
Conditions
Obesity
Interventions
Diet and Exercise
Behavioral
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
30 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 6, 2026, 6:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of an Amino Acid Supplement on Glucose Levels in Obese Subjects

NCT03715010
View directory record Official record
Conditions
Pre-diabetes, Obese, Glucose Intolerance
Interventions
BCAA
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2019 · Synced Oct 6, 2026, 6:55 PM EDT