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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Impairment of Speech Clear all
Completed No phase listed Observational

Effects of Stimulus Validity on Speech Recognition

NCT00013364
View directory record Official record
Conditions
Hearing Impaired
Interventions
Talker variability
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Open-canal Behind-the-Ear Hearing Aids and Traditional In-the-ear Hearing Aids.

NCT00727909
View directory record Official record
Conditions
Hearing Loss
Interventions
Hearing Aid Treatments
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 85 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Bay Pines, Florida • Mountain Home, Tennessee • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Sep 29, 2026, 6:05 AM EDT
Not yet recruiting Not applicable Interventional

Effects of Semantic Context on Criterion-learning Naming Treatment in Aphasia

NCT07673198
View directory record Official record
Conditions
Aphasia
Interventions
Criterion-learning practice
Behavioral
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 89 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 29, 2026, 6:05 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - FUTURE Extension

NCT04951284
View directory record Official record
Conditions
Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes), Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
Novoic Limited
Industry
Eligibility
50 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Working on Rapid Language Development in Toddlers

NCT01975922
View directory record Official record
Conditions
Language Developmental Disorders
Interventions
Enhanced Milieu Teaching
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
24 Months to 42 Months
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Sep 29, 2026, 6:05 AM EDT
Completed No phase listed Observational

Measures of Motor Impairment in Early Parkinson's Disease

NCT00291265
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
30 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Not applicable Interventional

The "Let's Talk Tech" Tool to Support Decision Making About Technology Use

NCT06817122
View directory record Official record
Conditions
Dementia, Mild, Mild Cognitive Impairment (MCI)
Interventions
Let's Talk Tech
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Age-related Correlates of Treatment for Late-acquired Sounds

NCT03663972
View directory record Official record
Conditions
Speech Sound Disorder, Phonology Disorder, Phonology Impairment, Phonological Disorder, Articulation Disorders in Children, Developmental Phonological Disorder, Speech Disorders, Speech Delay, Articulation Disorders, Developmental
Interventions
articulation therapy, phonologic treatment
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
4 Years to 8 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Sep 29, 2026, 6:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

NCT06405594
View directory record Official record
Conditions
Aphasia, Acquired, Stroke, Healthy Aging
Interventions
Language Condition
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2024 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Phase 3 Interventional

Melodic-Intonation-Therapy and Speech-Repetition-Therapy for Patients With Non-fluent Aphasia

NCT00903266
View directory record Official record
Conditions
Aphasia, Stroke, Cerebrovascular Accident, Apoplexy, Cerebral Infarction
Interventions
Melodic Intonation Therapy, Speech-Repetition-Therapy
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 20, 2020 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Phase 1Phase 2 Interventional

OTO-413 in Subjects With Speech-in-Noise Hearing Impairment

NCT04129775
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
OTO-413, Placebo
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
21 Years to 64 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
8
States / cities
Colorado Springs, Colorado • Hollywood, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Network Modulation in Alzheimer's Disease

NCT04045990
View directory record Official record
Conditions
Alzheimer Disease, Primary Progressive Aphasia, Mild Cognitive Impairment
Interventions
repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Sep 29, 2026, 6:05 AM EDT
Recruiting Not applicable Interventional

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

NCT07499570
View directory record Official record
Conditions
Mild Cognitive Impairment, Dementia, BPSD, BPSD (Behavioral and Psychological Symptoms of Dementia), Reminiscence Therapy
Interventions
Smart Virtual Reminiscence Therapy, Music Therapy
Device · Other
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 29, 2026, 6:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Perception of Speech in Context by Listeners With Healthy and Impaired Hearing

NCT06465979
View directory record Official record
Conditions
Hearing, Hearing Loss
Interventions
Speech Manipulation
Behavioral
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 65 Years
Enrollment
680 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
2
States / cities
Minneapolis, Minnesota • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Singing in Groups for Parkinson's Disease; A Pilot Study of Group Singing Therapy for PD-related Voice/Speech Impairment

NCT01163331
View directory record Official record
Conditions
Voice Quality and Voice Loudness Associated With Parkinson's Disease
Interventions
Singing Therapy
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
30 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Project PAIR: Parent-implemented Articulation Intervention With Recast

NCT06936696
View directory record Official record
Conditions
Hearing Impaired Children
Interventions
Broad Target Speech Recast, Traditional Speech Therapy
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
4 Years to 10 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 29, 2026, 6:05 AM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment

NCT02809118
View directory record Official record
Conditions
Hearing Loss, Idiopathic Sudden Sensorineural
Interventions
AM-111 0.4 mg/ml, AM-111 0.8 mg/ml, Placebo
Drug · Other
Lead sponsor
Auris Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
38
States / cities
Birmingham, Alabama • Escondido, California • Fresno, California + 34 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Sep 29, 2026, 6:05 AM EDT
Completed No phase listed Observational

Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory Center

NCT01465360
View directory record Official record
Conditions
Alzheimer's Disease, Mild Cognitive Impairment, Vascular Dementia, Fronto-temporal Dementia, Primary Progressive Aphasia, Parkinson' Disease Dementia, Mixed Dementia
Interventions
Not listed
Lead sponsor
Exonhit
Industry
Eligibility
21 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
3
States / cities
Las Vegas, Nevada • Cleveland, Ohio • Lakewood, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 5, 2012 · Synced Sep 29, 2026, 6:05 AM EDT
Not listed Not applicable Interventional

Hear Me Read 2021 Clinical Trial

NCT05245799
View directory record Official record
Conditions
Hearing Loss, Deafness, Hearing Disorders in Children, Hearing Impaired Children, Speech Therapy, Speech Disorders in Children, Literacy
Interventions
Speech Language Therapy, Digital Software Application
Behavioral
Lead sponsor
Prasanth Pattisapu
Other
Eligibility
3 Years to 5 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 29, 2023 · Synced Sep 29, 2026, 6:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping

NCT04928976
View directory record Official record
Conditions
Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes), Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
Novoic Limited
Industry
Eligibility
50 Years to 85 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Anomia Treatment Predictors

NCT06619756
View directory record Official record
Conditions
Anomia (Word-Finding Impairment), Aphasia
Interventions
Phonomotor Treatment (PMT), Phonological Components Analysis (PCA)
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 29, 2026, 6:05 AM EDT
Active, not recruiting Not applicable Interventional

HD-tDCS for Phonological Impairment in Aphasia

NCT06010030
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Targeted Transcranial Direct Current Stimulation, Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 29, 2026, 6:05 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss

NCT04462198
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
PIPE-505, Placebo
Drug
Lead sponsor
Contineum Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
8
States / cities
Torrance, California • Boca Raton, Florida • New Albany, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Sep 29, 2026, 6:05 AM EDT
Terminated No phase listed Observational

Hereditary Deficits in Auditory Processing Leading to Language Impairment

NCT00004570
View directory record Official record
Conditions
Auditory Perceptual Disorder, Language Delay, Language Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
6 Years to 85 Years
Enrollment
875 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Sep 29, 2026, 6:05 AM EDT