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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Implant Infection Clear all
Completed Phase 3 Interventional Results available

A Study of an Antibiotic Implant in General Surgical Subjects at Higher Risk for Surgical Wound Infection

NCT00600925
View directory record Official record
Conditions
Colorectal Surgery, Surgical Wound Infection
Interventions
gentamicin-collagen sponge dipped in saline
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
39
States / cities
Florence, Alabama • Mobile, Alabama • Laguna Hills, California + 36 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Jul 22, 2026, 11:08 PM EDT
Withdrawn Not applicable Interventional

Dynamic Laryngotracheal Separation for Aspiration

NCT00580346
View directory record Official record
Conditions
Aspiration Pneumonia
Interventions
Placement of laryngeal implant
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Jul 22, 2026, 11:08 PM EDT
Recruiting No phase listed Observational

Molecular Mechanisms Associated With Breast Implant Complications

NCT05736354
View directory record Official record
Conditions
Breast Implant; Complications, Infection or Inflammation
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
3
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 22, 2026, 11:08 PM EDT
Not yet recruiting Not applicable Interventional

Antibiotic-coated Braided Suture Study

NCT07322289
View directory record Official record
Conditions
Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Suture
Interventions
VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 89 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 22, 2026, 11:08 PM EDT
Not listed No phase listed Observational

Serum Based Diagnosis of and Monitoring of Infection Recovery in Orthopedic Spine Implant Infections

NCT04897971
View directory record Official record
Conditions
Staphylococcus Aureus Infection, Surgical Site Infection, Orthopedic Procedures, Spine
Interventions
Medium enriched for newly synthesized antibodies in spine infection
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Phase 1 Interventional

Bacterial Biofilms in Reconstructive Breast Prostheses Following Mastectomy

NCT03213249
View directory record Official record
Conditions
Breast Implant Infection, Mammoplasty
Interventions
Normal saline, Cefazolin, Skin biopsy, Bilateral skin- or nipple-sparing mastectomies, Tissue expander, Breast implant, Autologous flap, Acellular dermal matrix sling, Gentamicin, Bacitracin
Other · Drug · Procedure + 1 more
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

StaphVAX Immunogenicity in Orthopedic Implant Patients

NCT00211926
View directory record Official record
Conditions
Staphylococcal Infections, Joint Prosthesis
Interventions
S. aureus Type 5 & 8 Capsular Polysaccharide Conjugate, placebo
Biological
Lead sponsor
Nabi Biopharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 3, 2008 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Phase 4 Interventional Results available

Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomy

NCT01244126
View directory record Official record
Conditions
Otitis Media
Interventions
Intranasal fentanyl, morphine IM, IV morphine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
6 Months to 6 Years
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2016 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adhesive Tape Placement on Patients' Masks in the Emergency Department Increases Compliance of Proper Face Mask Use

NCT04812184
View directory record Official record
Conditions
Covid19
Interventions
Tape Face Mask
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study Dynamic Haptic Robotic Trainer (DHRT) and DHRT+ for Central Venous Catherization Insertion Training for Surgical Residents

NCT04541446
View directory record Official record
Conditions
Central Line Complication, Central Line Infection
Interventions
Dynamic Haptic Robotic Trainer (DHRT), Advanced Dynamic Haptic Robotic Trainer (DHRT+)
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
773 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Evaluation of the Middle Turbinate Implant for Affixing the Middle Turbinate to the Nasal Septum

NCT00896883
View directory record Official record
Conditions
Sinusitis
Interventions
Middle Turbinate Implant
Device
Lead sponsor
ENTrigue Surgical, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
4
States / cities
Sewell, New Jersey • Boerne, Texas • College Station, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2012 · Synced Jul 22, 2026, 11:08 PM EDT
Terminated No phase listed Observational

Natural History Study of Incidence of Otorrhea Following Tympanostomy Tube Insertion in Children 6 Months to 12 Years

NCT01111877
View directory record Official record
Conditions
Otorrhea
Interventions
Not listed
Lead sponsor
Alcon Research
Industry
Eligibility
6 Months to 12 Years
Enrollment
1,389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Feb 1, 2012 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Single Incision Laparoscopy

NCT00616616
View directory record Official record
Conditions
Appendicitis, Cholelithiasis, Malignant Hypertension
Interventions
single incision laparoscopic surgery
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Phase 4 Interventional

Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis

NCT00000894
View directory record Official record
Conditions
Cytomegalovirus Retinitis, HIV Infections
Interventions
Cidofovir, Probenecid, Ganciclovir
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
12
States / cities
Los Angeles, California • Miami, Florida • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2011 · Synced Jul 22, 2026, 11:08 PM EDT
Not listed Not applicable Interventional

Umbilical Cord Care for the Prevention of Colonization

NCT01893060
View directory record Official record
Conditions
Line Insertion Site, Central Line-associated Bloodstream Infection (CLABSI)
Interventions
Povidone-Iodine, Chlorhexidine gluconate, Pluronic Cream, control
Drug · Other
Lead sponsor
University of Virginia
Other
Eligibility
Up to 7 Days
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 1, 2013 · Synced Jul 22, 2026, 11:08 PM EDT
Completed No phase listed Observational

Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury

NCT02200120
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2015 · Synced Jul 22, 2026, 11:08 PM EDT
Terminated Phase 2 Interventional

CTI-01 (Ethyl Pyruvate) Safety and Complication Prevention in Cardiac Surgery Patients on Cardiopulmonary Bypass (CPB)

NCT00107666
View directory record Official record
Conditions
Coronary Disease, Heart Valve Diseases
Interventions
CTI-01 (ethyl pyruvate)
Drug
Lead sponsor
Critical Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
17
States / cities
Laguna Hills, California • Los Angeles, California • San Francisco, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2006 · Synced Jul 22, 2026, 11:08 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Placement of Nasogastric Tubes for Gastric Decompression in Patients With Bronchiolitis

NCT04480970
View directory record Official record
Conditions
Bronchiolitis
Interventions
Nasogastric tube placement
Device
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
1 Day to 23 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Compare Different Soft Tissue Grafts at the Time of Lateral Ridge Augmentation Procedure.

NCT03774888
View directory record Official record
Conditions
Bone Graft; Complications, Infection or Inflammation, Ridge Deficency, Dental Implant
Interventions
Connective tissue graft at time of bone graft, Acellular Demal Matrix at time of bone graft, No soft tissue grafting at time of bone graft
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Jul 22, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Reusable Versus Disposable Draping System in Breast Reconstruction Surgery

NCT01176786
View directory record Official record
Conditions
Mastectomy, Infections, Breast Reconstruction
Interventions
Culture Swabs, Rodac Plate Cultures
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Jul 22, 2026, 11:08 PM EDT
Enrolling by invitation Not applicable Interventional

Treatment of Acute Periprosthetic Joint Infection Comparing Single and Planned Double-Debridement Antibiotics and Implant Retention Followed by Chronic Antibiotic Suppression

NCT05640336
View directory record Official record
Conditions
Periprosthetic Joint Infection
Interventions
Single Debridement, Antibiotics and Implant Retention, Planned Double Debridement, Antibiotics and Implant Retention
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Jul 22, 2026, 11:08 PM EDT
Recruiting Phase 2Phase 3 Interventional

Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

NCT07214311
View directory record Official record
Conditions
Prosthetic-joint Infection
Interventions
PLG0206, Placebo
Drug
Lead sponsor
Peptilogics
Industry
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
13
States / cities
Sarasota, Florida • Tamarac, Florida • Baltimore, Maryland + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 22, 2026, 11:08 PM EDT
Withdrawn Not applicable Interventional

Proper Duration of Suppressive Antibiotic Therapy After Debridement, Antibiotics, and Implant Retention

NCT05495815
View directory record Official record
Conditions
Periprosthetic Joint Infection, Antibiotic Suppression
Interventions
6 months of SAT, 12 months of SAT, Indefinite SAT
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jul 22, 2026, 11:08 PM EDT
Active, not recruiting No phase listed Observational

REMBRANDT: REcovery of the MicroBiome fRom Antibiotics for Dental implanTs

NCT05622721
View directory record Official record
Conditions
Dysbiosis, Clostridium Difficile, Pet-Human Bonding, Antibiotic-Associated Colitis
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jul 22, 2026, 11:08 PM EDT