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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:16 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 175 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Implantable Cardioverter Defibrillator (ICD) Clear all

Conditions: Sarcoidosis of the Heart, Cardiomyopathy
Interventions: Not listed
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Cardiovascular Disease
Interventions: Not listed
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: Not listed
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Myocardial Infarction, Arrhythmia, Ventricular, Ischemic Cardiomyopathy
Interventions: T Wave Alternans Test; Procedure
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: Not listed
Enrollment: 656 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 47
States / cities: Mobile, Alabama • Phoenix, Arizona • Walnut Creek, California + 44 more

Conditions: Atrial Fibrillation, Implantable Cardioverter Defibrillator
Interventions: Breathing exercise; Behavioral
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Lead Extraction Procedures
Interventions: Not listed
Lead sponsor: Oregon Health and Science University; Other
Eligibility: Not listed
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Cardiomyopathies, Gender, Implantable Defibrillator User
Interventions: Not listed
Lead sponsor: Biotronik, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 49
States / cities: Birmingham, Alabama • Fairhope, Alabama • Rancho Mirage, California + 41 more

Conditions: Heart Failure, Implantable Defibrillator User, Ventricular Arrythmia
Interventions: Not listed
Lead sponsor: Larisa Tereshchenko; Other
Eligibility: 18 Years to 89 Years
Enrollment: 3,471 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 6
States / cities: Los Angeles, California • Stanford, California • Aurora, Colorado + 2 more

Conditions: Congestive Heart Failure, Coronary Artery Disease, Myocardial Infarction
Interventions: MyoCell™ Autologous Myoblasts; Drug
Lead sponsor: Bioheart, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 5
States / cities: Fort Lauderdale, Florida • Atlanta, Georgia • Chicago, Illinois + 2 more

Conditions: Shock
Interventions: ICD/ CRT-D; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 1,670 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Coronary Artery Disease
Interventions: Fortify® ST, Fortify Assura® ST, Ellipse® ST family of devices; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 2,258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 97
States / cities: Birmingham, Alabama • Huntsville, Alabama • Mesa, Arizona + 85 more

Conditions: Anxiety Disorder in Conditions Classified Elsewhere
Interventions: mindfulness based intervention (MBI), usual care; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 21 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Heart Failure, ICD, Chronotropic Incompetence
Interventions: CLS Mode on Biotronik CRT-D, Accelerometer Mode on Biotronik CRT-D; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 99 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Heart Failure
Interventions: Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 684 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 34
States / cities: Huntsville, Alabama • Anchorage, Alaska • Redwood City, California + 31 more

Conditions: Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
Interventions: Device; Device
Lead sponsor: Medtronic; Industry
Eligibility: Not listed
Enrollment: 20,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1983 – 2040
U.S. locations: 114
States / cities: Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 111 more

Conditions: Ventricular Tachycardia
Interventions: amiodarone, sotalol, Biosense Webster's NAVI-STAR Thermo-Cool; Drug · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 5
States / cities: Baltimore, Maryland • Durham, North Carolina • Columbus, Ohio + 2 more

Conditions: Tachyarrhythmias, Sudden Cardiac Death, Heart Failure
Interventions: SJ4 connector and RV high voltage SJ4 lead; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 1,701 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Shared Decision-making
Interventions: Arm A: Online, patient-facing decision-making aid (app) with personalized risk information., Arm B - Online, patient-facing decision-making app without personalized risk information., Arm C - Usual Care/No Device; Device · Other
Lead sponsor: Stanford University; Other
Eligibility: 60 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: San Francisco, California • Greenville, North Carolina

Conditions: Tachycardia, Ventricular
Interventions: Bispectral index monitoring, Ramsey Sedation Scale; Device · Other
Lead sponsor: Baystate Medical Center; Other
Eligibility: 21 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Primary Prevention of Sudden Cardiac Arrest, Secondary Prevention of Sudden Cardiac Arrest
Interventions: S-ICD System; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: Not listed
Enrollment: 1,766 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2021
U.S. locations: 87
States / cities: Huntsville, Alabama • Mesa, Arizona • Phoenix, Arizona + 72 more

Conditions: Ventricular Arrhythmia
Interventions: Eleclazine, Placebo to match eleclazine; Drug
Lead sponsor: Gilead Sciences; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 313 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 37
States / cities: Mesa, Arizona • Long Beach, California • Los Angeles, California + 32 more

Conditions: Arrhythmias, Cardiac
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: 9 Years and older
Enrollment: 1,509 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Magnetic Resonance Imaging (MRI)
Interventions: Blood sample collection; Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Heart Failure, Tachycardia, Ventricular
Interventions: St. Jude Medical Optisure Lead; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 1,735 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 46
States / cities: Birmingham, Alabama • Phoenix, Arizona • Jonesboro, Arkansas + 42 more

Conditions: Ventricular Tachycardia
Interventions: MRI guided VT ablation, Increased dose of amiodarone; Procedure · Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 99 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Portland, Oregon

Search by objective public record fields.

Implantable Cardiac Defibrillators for the Prevention of Sudden Death in Patients With Cardiac Sarcoidosis

Technology Dependency and Health-Related Quality of Life

MASTER I - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients

Breathing Intervention for Cardiac Anxiety

Pacemaker and Defibrillator Lead Extraction Registry

Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy

Global Electrical Heterogeneity and Clinical Outcomes

Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection

Programming Implantable Cardioverter Defibrillators in Patients With Primary Prevention Indication

ST Monitoring to Detect Acute Coronary Syndrome Events in Implantable Cardioverter Defibrillator Patients

A Mindfulness-based Intervention for Treatment of Anxiety in ICD (Implantable Cardioverter Defibrillator) Patients

Comparing Rate Response With CLS Versus Accelerometer ICD Settings in Heart Failure Patients With BIOTRONIK CRT-Ds

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Pilot Study of Catheter Ablation for Ventricular Tachycardia in Patients With an Implantable Cardioverter Defibrillator

SJ4 Post Approval Study in Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Defibrillator Patients

Evaluating a Digital Aid to Improve ICD Decisions

Bispectral Index Monitoring During Testing in the Electrophysiology Lab

S-ICD® System Post Approval Study

Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator

Clinically Indicated Magnetic Resonance Imaging in Patients With Cardiac Devices

Myocardial Injury in Patients With Cardiac Implantable Electronic Devices Following Magnetic Resonance Imaging

Optisure Lead Post Approval Study

Anti-arrhythmic Medication v. MRI-Merge Ablation in the Treatment of Ventricular Tachycardia