Efficacy and Safety Evaluation of Azimilide Dihydrochloride in Patients With Implantable Cardioverter Defibrillators
Public ClinicalTrials.gov record NCT00035490. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Implantable cardioverter defibrillators (ICDs) have been developed to treat ventricular tachycardia or fibrillation (abnormal heart rhythms) by electrical shock or by pacing the heart. ICD therapy is established as highly effective for stopping life-threatening arrhythmias, but it does not preclude the use of anti-arrhythmic drugs for prevention and to decrease the frequency of ICD shocks. The safety and effectiveness of oral azimilide dihydrochloride in reducing the frequency of ICD shocks has been investigated previously in a placebo-controlled study in patients with ICDs. These results need to be confirmed in this larger double-blind, placebo-controlled study with approximately 600 patients.
Study identification
- NCT ID
- NCT00035490
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 633 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2001 (Type not available)
- Primary completion
- Apr 2004 (Actual)
- Completion
- Apr 2004 (Actual)
- Last update posted
- Oct 3, 2011
2001 – 2004
United States locations
- U.S. sites
- 78
- U.S. states
- 33
- U.S. cities
- 70
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Heart Group | Mobile | Alabama | 36608 | — |
| Tri-City Cardiology Consultants, P.C. | Mesa | Arizona | 85206 | — |
| UAMS Dept of Cardiology | Little Rock | Arkansas | 72205 | — |
| ATC/Cardio Medical Grp | Beverly Hills | California | 90210 | — |
| Loma Linda Univ. Med. Ctr. | Loma Linda | California | 92354 | — |
| Good Samaritan Hospital | Los Angeles | California | 90017 | — |
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| Regional Cardiology Associates | Sacramento | California | 95819 | — |
| Cardiac Arrythmia Associates | San Diego | California | 92037 | — |
| UCSD Medical Center | San Diego | California | 92103 | — |
| Memorial Hospital | Colorado Springs | Colorado | 80910 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Florida Arrythmia Consultants | Fort Lauderdale | Florida | 33308 | — |
| Southwest Florida Health Group | Fort Myers | Florida | 33919 | — |
| Jacksonville Heart Center | Jacksonville | Florida | 32250 | — |
| The Watson Clinic, LLP | Lakeland | Florida | 33805 | — |
| Univ. Miami Jackson Mem. med. Ctr. | Miami | Florida | 33136 | — |
| Florida Heart Institute | Orlando | Florida | 32803 | — |
| Memorial Health Systems/Cardiology Research Associates | Ormond Beach | Florida | 32174 | — |
| Loyola University Med. Ctr. | Maywood | Illinois | 60153 | — |
| University of Iowa Hospital | Iowa City | Iowa | 52242 | — |
| Mid-America Cardiology c/o KU medical Ctr | Kansas City | Kansas | 66160 | — |
| University Cardiology | Louisville | Kentucky | 40202 | — |
| Louisville Cardiology Medical Group, PSC | Louisville | Kentucky | 40207 | — |
| LSU Health Sciences Center | Shreveport | Louisiana | 71130 | — |
| Maine Cardiology Assoc. | Portland | Maine | 04102 | — |
| Mid-Atlantic Cardiovascular Associates | Baltimore | Maryland | 21204 | — |
| St Elizabeth Medical Center | Boston | Massachusetts | 02135 | — |
| Lahey Hitchcock Medical Ctr. | Burlington | Massachusetts | 01805 | — |
| Baystate Medical Center-Cardiology Research | Springfield | Massachusetts | 01199 | — |
| University of Mass. Medical Ctr. Division of Cardiovascular Medicine | Worcester | Massachusetts | 01655 | — |
| SMDC Education Research | Duluth | Minnesota | 55805 | — |
| University of Minnesota-Cardiology | Minneapolis | Minnesota | 55455 | — |
| Nevada Cardiology | Las Vegas | Nevada | 89109 | — |
| Morristown Memorial Hospital | Morristown | New Jersey | 07962 | — |
| Atlantic Health Systems | Passaic | New Jersey | 07055 | — |
| Arrhythmia and Pacemaker Consultants | West Orange | New Jersey | 07052 | — |
| Brookdale University Hospital | Brooklyn | New York | 111212 | — |
| Huntington Hospital | Huntington | New York | 11743 | — |
| Cardiology Assoc., PC | Johnson City | New York | 13797 | — |
| St. Lukes/Roosevelt Hospital Center | New York | New York | 10025 | — |
| The Mt Sinai Medical Ctr. | New York | New York | 10029 | — |
| Rochester Cardiopulmonary Group | Rochester | New York | 14621 | — |
| University of Rochester Strong mem. Hospital | Rochester | New York | 14642 | — |
| Buffalo Cardiology & Pulmonary Assoc. | Williamsville | New York | 14221 | — |
| Mid Carolina Cardiology | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Ctr. | Durham | North Carolina | 27710 | — |
| Wake Forest School of Medicine | Winston-Salem | North Carolina | 27157 | — |
| United HealthNetwork/Ohio Heart Center | Canton | Ohio | 44718 | — |
| The Lindnar Clinical Trial Center | Cincinnati | Ohio | 45219 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Midwest Cardio Res. Foundation | Columbus | Ohio | 43214 | — |
| Dayton Cardiac EP | Dayton | Ohio | 45406 | — |
| Medical College of Ohio | Toledo | Ohio | 43614 | — |
| Oklahoma Heart Institute | Tulsa | Oklahoma | 74104 | — |
| Cardiovascular Assoc. | Eugene | Oregon | 97401 | — |
| Doylestown Medical Hospital | Doylestown | Pennsylvania | 18901 | — |
| Hershey Med. Ctr.-Div. Cardiology | Hershey | Pennsylvania | 17033 | — |
| Lancaster Heart Foundation | Lancaster | Pennsylvania | 17603 | — |
| Univ of PA/Presbyterian Hospital | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Barry Alpert, MD, FACC | Pittsburgh | Pennsylvania | 15224 | — |
| Blackstone Cardiology Assoc. P.C. | Pawtucket | Rhode Island | 02860 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| South Carolina Heart Center | Columbia | South Carolina | 29204 | — |
| Mid-State Cardiology | Nashville | Tennessee | 37203 | — |
| Heart Place/Baylor University of Medicine | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center at Dallas | Dallas | Texas | 75390-9047 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Utah Medical Ctr. | Salt Lake City | Utah | 84132 | — |
| U. OF Virginia/Dept of Cardiology | Charlottesville | Virginia | 22908 | — |
| The Cardiovascular Grp./Attn: Mandy Murphy | Fairfax | Virginia | 22031 | — |
| Medical College of VA | Richmond | Virginia | 23219 | — |
| Inland Cardiology/The Heart Inst. | Spokane | Washington | 99204 | — |
| Cardiology Associates of Green Bay | Green Bay | Wisconsin | 54301 | — |
| Wisconsin Ctr for Clinical Research | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 64 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00035490, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 3, 2011 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00035490 live on ClinicalTrials.gov.