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ClinicalTrials.gov public records Last synced Oct 2, 2026, 1:23 AM EDT

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Showing 25–48 of 189 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Implantable Cardioverter Defibrillator Implanted Clear all
Not listed Phase 1 Interventional

Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection

NCT00050765
View directory record Official record
Conditions
Congestive Heart Failure, Coronary Artery Disease, Myocardial Infarction
Interventions
MyoCell™ Autologous Myoblasts
Drug
Lead sponsor
Bioheart, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
5
States / cities
Fort Lauderdale, Florida • Atlanta, Georgia • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2006 · Synced Oct 2, 2026, 1:23 AM EDT
Not listed No phase listed Observational

CarDiac MagnEtic Resonance for Primary Prevention Implantable CardioVerter DebrillAtor ThErapy: an International Registry (DERIVATE)

NCT03352648
View directory record Official record
Conditions
Heart Failure, Left Ventricular Systolic Dysfunction
Interventions
Not listed
Lead sponsor
Gianluca Pontone, MD, PhD
Other
Eligibility
Not listed
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2020
U.S. locations
2
States / cities
Chicago, Illinois • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Oct 2, 2026, 1:23 AM EDT
Terminated Phase 3 Interventional

Efficacy and Safety Study of Azimilide on the Incidence of Cardiovascular Hospitalizations/Emergency Department Visits or Cardiovascular Death in Patients With an Implantable Cardioverter Defibrillator (ICD) (SHIELD-2)

NCT01464476
View directory record Official record
Conditions
Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases, Implantable Cardioverter Defibrillator
Interventions
Azimilide Dihydrochloride, Placebo
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
83
States / cities
Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 72 more
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Electronic Patient Notification of Remote ICD Data: Impact of Patient Engagement on Outcomes in the Merlin.Net™

NCT02989090
View directory record Official record
Conditions
Implantable Cardioverter-Defibrillator, Health Information Exchange, Electronic Health Records, Patient Participation
Interventions
Receive Detailed ICD Information-electronic, Receive Detailed ICD Information-paper
Other
Lead sponsor
Parkview Hospital, Indiana
Other
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Oct 2, 2026, 1:23 AM EDT
Completed No phase listed Observational

Risk of Life-threatening Heart Rhythm Disturbances in Siblings

NCT00498524
View directory record Official record
Conditions
Defibrillators, Implantable, Myocardial Infarction, Tachycardias, Ventricular
Interventions
ICD
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2,047 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 7, 2012 · Synced Oct 2, 2026, 1:23 AM EDT
Terminated Not applicable Interventional Results available

Pediatric Lead Extractability and Survival Evaluation (PLEASE)

NCT00335036
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Cardiomyopathy, Long QT Syndrome, Congenital Heart Disease
Interventions
ICD lead implant, Thin leads
Device
Lead sponsor
Charles Berul
Other
Eligibility
1 Year to 55 Years
Enrollment
748 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Phase 3 Interventional

Ovatio DR and VR Implantable Cardioverter Defibrillators Post-approval Study

NCT00586378
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Ovatio DR and Ovatio VR
Device
Lead sponsor
ELA Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 2, 2012 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers

NCT04994782
View directory record Official record
Conditions
Implantable Defibrillator User, Terminal Illness
Interventions
GAME-EOL
Behavioral
Lead sponsor
Debra Moser
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Phase 2 Interventional Results available

Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator

NCT02104583
View directory record Official record
Conditions
Ventricular Arrhythmia
Interventions
Eleclazine, Placebo to match eleclazine
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 80 Years
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
37
States / cities
Mesa, Arizona • Long Beach, California • Los Angeles, California + 32 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 2, 2026, 1:23 AM EDT
Recruiting No phase listed Observational

Left Ventricular Structural Predictors of Sudden Cardiac Death

NCT01076660
View directory record Official record
Conditions
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2030
U.S. locations
2
States / cities
Newark, Delaware • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 2, 2026, 1:23 AM EDT
Recruiting No phase listed Observational

Pacemaker and Defibrillator Lead Extraction Registry

NCT03847025
View directory record Official record
Conditions
Lead Extraction Procedures
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Not applicable Interventional

The Efficacy of Single Coil Defibrillation Leads for Internal Cardioversion of Atrial Fibrillation

NCT03164395
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Internal Cardioversion, External Cardioversion
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 99 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 2, 2026, 1:23 AM EDT
Enrolling by invitation Not applicable Interventional

Magnetic Resonance Imaging (MRI) in Patients With Pacemakers and Implanted Cardioverter Defibrillators

NCT02888353
View directory record Official record
Conditions
Device:MRI
Interventions
Device: MRI
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years to 100 Years
Enrollment
4,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 2, 2026, 1:23 AM EDT
Terminated Phase 4 Interventional Results available

Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk

NCT00559988
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter, Stroke, Embolism, Systemic Arterial, Major Bleeding
Interventions
Home Monitoring Guided OAC, Physician-Directed OAC
Drug
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,718 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
73
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Anaheim, California + 70 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Oct 2, 2026, 1:23 AM EDT
Terminated No phase listed Observational Results available

ST Segment Detection Study

NCT00930969
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
ICD
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
17
States / cities
Anchorage, Alaska • Brandon, Florida • Orlando, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Phase 3 Interventional Results available

Ranolazine Implantable Cardioverter-Defibrillator Trial

NCT01215253
View directory record Official record
Conditions
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy, Heart Failure
Interventions
Ranolazine
Drug
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
1,012 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
83
States / cities
Tucson, Arizona • Little Rock, Arkansas • East Palo Alto, California + 70 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Phase 1 Interventional

LifeSkills Video Training in Patients About to Receive an Automatic Implantable Cardioverter-Defibrillator (AICD)

NCT01686490
View directory record Official record
Conditions
Focus Whether After Implant Pre-AICD Video Was Helpful
Interventions
Video/workbook for patients about to receive an AICD, LiveSkills Video/Workbook for patients about to receive an AICD
Behavioral
Lead sponsor
Williams LifeSkills
Industry
Eligibility
21 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2012 · Synced Oct 2, 2026, 1:23 AM EDT
Terminated Not applicable Interventional Results available

Effect of Posture on Left Ventricular (LV) Transvenous Lead Capture Thresholds (EXPECT)

NCT01520714
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Medtronic 4195 active fixation LV lead and Medtronic passive fixation LV lead
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2014 · Synced Oct 2, 2026, 1:23 AM EDT
Completed No phase listed Observational Results available

Medtronic Shock-Less Study on Physician Utilization of Shock Reduction Programming

NCT00856349
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Therapy Programming Report (TPR)
Behavioral
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
4,384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
83
States / cities
Anniston, Alabama • Phoenix, Arizona • Tucson, Arizona + 80 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2014 · Synced Oct 2, 2026, 1:23 AM EDT
Completed No phase listed Observational Results available

REPLACE: Implantable Cardiac Pulse Generator Replacement Registry

NCT00395447
View directory record Official record
Conditions
Device Replacement, Elective Replacement (ERI), Device Advisory, Device Upgrade, Postoperative Complications
Interventions
Straight-forward Device Replacement, Device Replacement with Upgrade
Procedure
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,744 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
71
States / cities
Birmingham, Alabama • Mesa, Arizona • Modesto, California + 58 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Phase 3 Interventional

Long Term Safety of 125 mg Per Day of Oral Azimilide in Patients With Implantable Cardioverter Defibrillator (ICDs)

NCT00751738
View directory record Official record
Conditions
Arrhythmias
Interventions
azimilide dihydrochloride
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
50
States / cities
Mobile, Alabama • Little Rock, Arkansas • La Jolla, California + 43 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Phase 3 Interventional

Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

NCT00673842
View directory record Official record
Conditions
Myocardial Infarction, Sudden Death
Interventions
Implantable Cardioverter Defibrillator + Usual Care, Usual care
Device · Other
Lead sponsor
University of Calgary
Other
Eligibility
18 Years to 80 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
29
States / cities
Huntsville, Alabama • Lakewood, Colorado • Tampa, Florida + 23 more
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Oct 2, 2026, 1:23 AM EDT
Completed Not applicable Interventional

Prospective Randomized Evaluation of an Ultra Conservative Approach to Implantable Defibrillator (ICD) Programming in Patients With a Left Ventricular Assist Device (LVAD).

NCT01977703
View directory record Official record
Conditions
Heart Failure
Interventions
Ultra Conservative ICD Programming, Traditional ICD Programming
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 16, 2017 · Synced Oct 2, 2026, 1:23 AM EDT
Completed No phase listed Observational

First Arrhythmia Collection of Transvenous and Simultaneous Subcutaneous Implantable Defibrillator Data

NCT01161589
View directory record Official record
Conditions
Ventricular Tachycardia, Ventricular Fibrillation, Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
3
States / cities
Chicago, Illinois • Charleston, South Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2017 · Synced Oct 2, 2026, 1:23 AM EDT