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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: In-Stent Restenosis Clear all
Completed Phase 2Phase 3 Interventional

Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stents to Treat De Novo Coronary Lesions

NCT00301522
View directory record Official record
Conditions
Coronary Stenosis
Interventions
TAXUS Paclitaxel-Eluting Coronary Stent, Slow-Formulation, Express2
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
1,108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
72
States / cities
Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 58 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2010 · Synced Sep 8, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional

Virtue® SAB in the Treatment of Coronary ISR Trial

NCT07045194
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Virtue Sirolimus AngioInfusion Balloon, AGENT™ Paclitaxel Drug-Coated Balloon
Device
Lead sponsor
Orchestra BioMed, Inc
Industry
Eligibility
18 Years and older
Enrollment
740 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
15
States / cities
Gainesville, Florida • Pensacola, Florida • Indianapolis, Indiana + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Phase 3 Interventional

Sirolimus-Eluting Stent vs. Intravascular Brachytherapy in In-Stent Restenotic Coronary Artery Lesions(SISR)

NCT00231257
View directory record Official record
Conditions
In-Stent Restenosis
Interventions
Sirolimus-Eluting Bx Velocity® Balloon Expandable Stent, Brachytherapy
Device · Procedure
Lead sponsor
Cordis US Corp.
Industry
Eligibility
18 Years and older
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 18, 2009 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Phase 4 Interventional

Study of the Xience V Everolimus-eluting Stent in Saphenous Vein Graft Lesions

NCT00911976
View directory record Official record
Conditions
Coronary Artery Bypass, Atherosclerosis
Interventions
Xience V coronary stent
Device
Lead sponsor
North Texas Veterans Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2012 · Synced Sep 8, 2026, 2:51 PM EDT
Active, not recruiting Not applicable Interventional

SELUTION SLR™ 014 In-stent Restenosis

NCT04280029
View directory record Official record
Conditions
Coronary Restenosis
Interventions
SELUTION SLR 014 DEB, Standard of Care
Device
Lead sponsor
M.A. Med Alliance S.A.
Industry
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
34
States / cities
Loma Linda, California • Los Angeles, California • Torrance, California + 30 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

In-Stent Restenosis Post-Approval Study

NCT02542267
View directory record Official record
Conditions
Peripheral Artery Disease, Vascular Disease
Interventions
Gore VIABAHN Endoprosthesis
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
20
States / cities
Miami, Florida • Honolulu, Hawaii • Rockford, Illinois + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

Lutonix® Drug Coated Balloon vs. Standard Balloon Angioplasty for Treatment of Femoropopliteal In-Stent Restenosis

NCT02063672
View directory record Official record
Conditions
Femoral Artery Stenosis, Femoral Artery Occlusion, Restenosis
Interventions
Lutonix DCB, Standard Uncoated Balloon Angioplasty Catheter
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
20
States / cities
Fairhope, Alabama • New Haven, Connecticut • Washington D.C., District of Columbia + 17 more
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Not applicable Interventional

STAR and Deferred Stenting Study

NCT05089864
View directory record Official record
Conditions
Coronary Occlusion, Coronary Stenosis, Coronary Restenosis
Interventions
Stent Placement Timing - Early, Stent Placement Timing - Late
Other
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

A Clinical Evaluation of Absorb™ Bioresorbable Vascular Scaffold (Absorb™ BVS) System in Chinese Population ~ ABSORB CHINA Randomized Controlled Trial (RCT)

NCT01923740
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Artery Stenosis, Coronary Disease, Coronary Stenosis
Interventions
XIENCE V EECSS, Absorb BVS System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Santa Clara, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

JetStream Atherectomy for the Treatment of In-stent Restenosis

NCT02730234
View directory record Official record
Conditions
Femoropopliteal In-stent Restenosis
Interventions
JetStream XC with balloon angioplasty
Device
Lead sponsor
Midwest Cardiovascular Research Foundation
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
13
States / cities
Denver, Colorado • Sebring, Florida • Downers Grove, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Sep 8, 2026, 2:51 PM EDT
Withdrawn No phase listed Observational

REWARDS- In-stent Restenosis

NCT03008772
View directory record Official record
Conditions
In-Stent Coronary Artery Restenosis
Interventions
Not listed
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 8, 2026, 2:51 PM EDT
Completed No phase listed Observational Results available

TurboPower + DCB Treatment of Femoropopliteal De Novo/ Restenotic and In-Stent Restenosis Lesions

NCT03306199
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Laser Atherectomy
Device
Lead sponsor
Spectranetics Corporation
Industry
Eligibility
Not listed
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houma, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 7, 2019 · Synced Sep 8, 2026, 2:51 PM EDT
Active, not recruiting Phase 3 Interventional Results available

A Clinical Trial to Assess the Agent Paclitaxel Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis (ISR)

NCT04647253
View directory record Official record
Conditions
In-Stent Restenosis
Interventions
AGENT DCB, PTCA balloon catheter
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
40
States / cities
Birmingham, Alabama • Tucson, Arizona • La Jolla, California + 33 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 8, 2026, 2:51 PM EDT
Completed No phase listed Observational Results available

XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS) China Single-Arm Study

NCT01894152
View directory record Official record
Conditions
Angioplasty, Cardiovascular Disease, Coronary Artery Disease, Coronary Heart Disease, Coronary Restenosis, Myocardial Infarction, Stent Thrombosis, Vascular Disease
Interventions
XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,002 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Santa Clara, California
Source: ClinicalTrials.gov public record
Updated May 25, 2020 · Synced Sep 8, 2026, 2:51 PM EDT
Completed No phase listed Observational

Genomics of In-Stent Restenosis

NCT00341562
View directory record Official record
Conditions
In-Stent Restenosis, Vascular Disease
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 8, 2026, 2:51 PM EDT
Not listed No phase listed Observational

Retrospective Long-term Safety and Efficacy Study of the Beta-Cath(TM) 3.5F System

NCT00852176
View directory record Official record
Conditions
Coronary In-stent Restenosis
Interventions
Not listed
Lead sponsor
Best Vascular, Inc.
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Phase 2 Interventional

Safety and Efficacy of the ZoMaxx™ Drug-Eluting Stent System in Coronary Arteries

NCT00140101
View directory record Official record
Conditions
Coronary Disease, Coronary Artery Disease, Coronary Restenosis
Interventions
ZoMaxx™ Drug-Eluting Coronary Stent System, TAXUS™ EXPRESS2™ Paclitaxel Eluting Coronary Stent
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,099 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
74
States / cities
Huntsville, Alabama • Gilbert, Arizona • La Jolla, California + 60 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2012 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

A Study to EXhibit Percutaneous Coronary Artery Dilatation With Non-Slip Element Balloon

NCT04985773
View directory record Official record
Conditions
Coronary Stenosis, Coronary Artery Stenosis, In-stent Restenosis
Interventions
Lacrosse NSE ALPHA coronary dilatation catheter
Device
Lead sponsor
Infraredx
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
10
States / cities
Palo Alto, California • Lexington, Kentucky • Maplewood, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Sep 8, 2026, 2:51 PM EDT
Not listed No phase listed Observational

Intra-stent Tissue Evaluation Within BMS and DES > 3 Years Since Implantation

NCT01835301
View directory record Official record
Conditions
In-stent Coronary Artery Restenosis
Interventions
Not listed
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 10, 2014 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Not applicable Interventional Results available

ABSORB III Randomized Controlled Trial (RCT)

NCT01751906
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Artery Stenosis, Coronary Disease, Coronary Stenosis
Interventions
Absorb BVS, XIENCE
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,008 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
190
States / cities
Birmingham, Alabama • Fairhope, Alabama • Montgomery, Alabama + 145 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Sep 8, 2026, 2:51 PM EDT
Completed No phase listed Observational

PROSPECT: An Imaging Study in Patients With Unstable Atherosclerotic Lesions

NCT00180466
View directory record Official record
Conditions
Coronary Disease, Coronary Artery Disease, Coronary Restenosis
Interventions
Not listed
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
697 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
22
States / cities
Phoenix, Arizona • San Jose, California • Stanford, California + 18 more
Source: ClinicalTrials.gov public record
Updated May 24, 2010 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Study Comparing Two Methods of Expanding Stents Placed in Legs of Diabetics With Peripheral Vascular Disease

NCT00827853
View directory record Official record
Conditions
PERIPHERAL VASCULAR DISEASE
Interventions
Conventional angioplasty balloon, cryoplasty balloon
Procedure
Lead sponsor
North Texas Veterans Healthcare System
Federal
Eligibility
21 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
4
States / cities
Davenport, Iowa • Oklahoma City, Oklahoma • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2013 · Synced Sep 8, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

NCT05908331
View directory record Official record
Conditions
In-Stent Restenosis, Cardiovascular Diseases, Coronary Artery Disease
Interventions
Sirolimus Drug Coated Balloon, Plan balloon Angioplasty (POBA)
Device
Lead sponsor
Concept Medical Inc.
Industry
Eligibility
18 Years to 110 Years
Enrollment
492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
27
States / cities
Birmingham, Alabama • Gilbert, Arizona • Los Angeles, California + 21 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 8, 2026, 2:51 PM EDT
Completed Phase 2Phase 3 Interventional

Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stent in the Treatment of In-Stent Restenosis

NCT00287573
View directory record Official record
Conditions
Coronary Restenosis
Interventions
TAXUS Express2, Brachytherapy (beta source)
Device · Procedure
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
488 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
40
States / cities
Birmingham, Alabama • La Jolla, California • Sacramento, California + 35 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2010 · Synced Sep 8, 2026, 2:51 PM EDT