Independent directory Public ClinicalTrials.gov records United States
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Showing 409–432 of 538 matching trials from the live ClinicalTrials.gov search.
Conditions
Negative-Pressure Wound Therapy
Interventions
dry gauze, The Prevena Incision Management System
Other · Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
583 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
10
States / cities
Hartford, Connecticut • Basking Ridge, New Jersey • Middletown, New Jersey + 7 more
Conditions
Open Surgical Wounds
Interventions
conventional closure, V-Loc 90
Device
Lead sponsor
Vladimir Grigoryants MD
Other
Eligibility
32 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Glendale, California
Completed Not applicable Interventional Accepts healthy volunteers

Cesarean Skin Incision Trial

NCT01897376
Conditions
Wound Complication
Interventions
Pfannenstiel incision, vertical skin incision
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
Galveston, Texas • Houston, Texas
Conditions
Diabetic Foot Ulcer, Surgical Wound
Interventions
Natrox® Oxygen Wound Therapy
Device
Lead sponsor
Inotec AMD Limited
Industry
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
19
States / cities
Los Angeles, California • Miami, Florida • Miami Lakes, Florida + 15 more
Conditions
Fractures, Open, Surgical Wound Infection
Interventions
Vancomycin
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chattanooga, Tennessee
Not listed No phase listed Observational Accepts healthy volunteers

Zonulin Biomarker for Diagnosis of Hip and Knee Infections

NCT04666519
Conditions
Surgical Site Infection, Zonulin
Interventions
Zonulin Biomarker
Diagnostic Test
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Dysbiosis, Gut -microbiota, Microbiome Analysis, Probiotic, Antibiotic Prophylaxis
Interventions
Placebo Capsule, Probiotic with Human Milk Oligosaccharides (HMO)
Drug · Dietary Supplement
Lead sponsor
Acibadem Maslak Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Surgical Wound Infection, Surgery, Colon
Interventions
Mild intraoperative hypercapnia (50 mmHg vs. 30 mmHg), Supplemental oxygen (80% vs. 30%), Dexamethasone, Placebo
Other · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
2
States / cities
Louisville, Kentucky • Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cesarean Trial of Staples vs. Sutures

NCT01211600
Conditions
Cesarean Section, Wound Complications, Patient Satisfaction, Pain Measurement
Interventions
Staples, Suture
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
Female only
Enrollment
746 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
New Haven, Connecticut • Philadelphia, Pennsylvania
Conditions
Cutaneous Ulcer, Diabetic Ulcer, Surgical Wound Dehiscence, Burns - Multiple, Pressure Ulcers, Mixed Ulcer, Ischemic Ulcer
Interventions
MTX-001 (Dermacyte Liquid)
Drug
Lead sponsor
Merakris Therapeutics
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Arvada, Colorado
Conditions
Surgery, Pneumonia, Surgical Site Infection
Interventions
Continuous Sternal Block, Opioid based analgesia
Device · Drug
Lead sponsor
Halyard Health
Industry
Eligibility
18 Years and older
Enrollment
647 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
8
States / cities
Birmingham, Alabama • Newark, Delaware • Lexington, Kentucky + 5 more
Conditions
Brow Ptosis, Surgical Wound
Interventions
Dermabond, Non-Absorbable Sutures
Device · Other
Lead sponsor
Cody Blanchard
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Gastro Esophageal Reflux
Interventions
Esophyx
Device
Lead sponsor
Peter G Mavrelis
Individual
Eligibility
18 Years to 80 Years
Enrollment
99 participants
Timeline
2014 – 2016
U.S. locations
2
States / cities
Merrillville, Indiana • Appleton, Wisconsin
Conditions
Surgical Site Infection
Interventions
Cephalexin, Placebo, Metronidazole
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Austin, Texas • Galveston, Texas
Conditions
Clavicle Fracture
Interventions
xrays
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Active, not recruiting Not applicable Interventional

Desara ® One Single Incision Sling 522 Study

NCT04772131
Conditions
Stress Urinary Incontinence
Interventions
Desara® One Single Incision Sling, Desara® Blue Transobturator Sling
Device
Lead sponsor
Caldera Medical, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
15
States / cities
Phoenix, Arizona • Tucson, Arizona • Hialeah, Florida + 12 more
Conditions
Cesarean Section, Surgical Site Infection, Wound Dehiscence, Seroma
Interventions
Steri-Strip™ Skin Closures, Standard Cesarean Wound Closure
Device · Procedure
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Moreno Valley, California
Conditions
Spine Surgery, Wounds Vac
Interventions
Wound Vac, Standard Dressing
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Phase 1 Interventional Accepts healthy volunteers

Tumescent Antibiotic Delivery Pharmacokinetics

NCT01046981
Conditions
Prevention of Surgical Site Infections
Interventions
Tumescent Antibiotic Delivery of cefazolin with or without metronidazole, Intravenous Antibiotic Delivery
Procedure
Lead sponsor
Klein, Jeffrey A., M.D.
Individual
Eligibility
21 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Juan Capistrano, California
Conditions
Surgical Wound Infection
Interventions
80% oxygen, 30% oxygen
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Louisville, Kentucky • Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Skin Prep Study

NCT01472549
Conditions
Surgical Site Infections
Interventions
Iodine-alcohol, Chlorhexidine-alcohol
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
1,147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Gingival Recession
Interventions
VISTA, STA
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reduction in IV Associated Contamination

NCT01426217
Conditions
Post-operative Infections
Interventions
Passive Bundle PSI (Problem Solving Innovations) Medical HubScrub, PSI Medical DocIt
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
594 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Lebanon, New Hampshire
Conditions
Surgical Wound
Interventions
PICO Single Use Negative Pressure Wound Therapy System, xeroform gauze
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama