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Showing 385–408 of 600 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?

NCT02007096
Conditions
Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications, Pain, Postoperative
Interventions
Transabdominal Plane Block, Non Transabdominal Plane Block
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Infection
Interventions
Spinal surgery
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 99 Years
Enrollment
6,959 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
2
States / cities
Miami, Florida
Conditions
Prosthetic-joint Infection, Dysbiosis
Interventions
Probiotic, Standard of care
Drug · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pre-incision Versus Post-incision Local Anesthetic During Robotic Sacrocolpopexy

NCT04996251
Conditions
Pain, Postoperative
Interventions
Bupivacaine Injection
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Manhasset, New York
Conditions
Cardiovascular Surgical Procedures, Arthroplasty, Replacement, Hysterectomy
Interventions
Quality improvement strategies
Behavioral
Lead sponsor
Agency for Healthcare Research and Quality (AHRQ)
Federal
Eligibility
Not listed
Timeline
2002 – 2005
U.S. locations
3
States / cities
Oakbrook Terrace, Illinois • Winston-Salem, North Carolina • Memphis, Tennessee
Terminated Not applicable Interventional Results available

Prophylactic NPWT to Reduce SSI in Colorectal Surgery

NCT03661814
Conditions
Surgical Wound Infection
Interventions
Prevena
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Study to Evaluate Safety and Effectiveness of Spinal Sealant

NCT00594035
Conditions
Spinal Procedure Requiring Dura Incision
Interventions
Spinal Sealant System, Standard of care
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Bedford, Massachusetts
Conditions
Osteoarthritis
Interventions
Mini Incision Approach, 2 Incision Approach
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Surgical Site Infection
Interventions
IrriSept System, No Intervention - Standard of Care (SoC) only
Device · Other
Lead sponsor
Irrimax Corporation
Industry
Eligibility
18 Years and older
Enrollment
627 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
17
States / cities
Tucson, Arizona • Los Angeles, California • Denver, Colorado + 14 more
Conditions
Carpal Tunnel Syndrome
Interventions
Splinting
Behavioral
Lead sponsor
Christine M. Kleinert Institute for Hand and Microsurgery
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
Louisville, Kentucky
Conditions
Postoperative Complications, Surgical Wound Infection, Surgical Wound Dehiscence
Interventions
acupuncture, sham acupuncture
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
San Francisco, California
Conditions
Traumatic Lacerations or Surgical Incisions
Interventions
BondEase, CWCD
Device · Procedure
Lead sponsor
OptMed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
6
States / cities
Orlando, Florida • Chicago, Illinois • Chevy Chase, Maryland + 3 more
Conditions
Surgical Site Infection
Interventions
Intrasite Vancomycin, IV Vancomycin
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Infection, Surgical Site
Interventions
Intraosseous Vancomycin Injection, Intravenous Vancomycin
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
19 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Conditions
Glycemic Control, Surgical Site Infections, Cardiac Complications, Length of Stay, Cost
Interventions
standard insulin protocol post-op (continuous IV insulin)
Drug
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Surgical Wound, Wound Heal, Wound of Skin, Scar
Interventions
Zinc containing suncreen
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Sacramento, California
Conditions
Cataract
Interventions
Phacoemulsification cataract extraction surgery, Small incision cataract surgery
Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years to 70 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Abscess, Wound Infection, Surgical Site Infection, Cellulitis
Interventions
Dalbavancin, Vancomycin / Linezolid
Drug
Lead sponsor
Durata Therapeutics Inc., an affiliate of Allergan plc
Industry
Eligibility
18 Years to 85 Years
Enrollment
573 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
55
States / cities
Anaheim, California • Azusa, California • Bellflower, California + 50 more
Conditions
Stress Urinary Incontinence
Interventions
Solyx Single Incision Sling System, Obtryx II Sling System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older · Female only
Enrollment
281 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
22
States / cities
Beverly Hills, California • Loma Linda, California • San Diego, California + 18 more
Conditions
Primary Anatomic or Reverse Total Shoulder Arthroplasty
Interventions
H2O2 application to incision
Other
Lead sponsor
University of Florida
Other
Eligibility
40 Years to 90 Years · Male only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Esophageal Subepithelial Lesions
Interventions
22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Scar, Breast Neoplasms, Breast Diseases, Surgical Wound
Interventions
Steri-strip
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
East Norriton, Pennsylvania • Philadelphia, Pennsylvania
Conditions
Cardiac Surgery, Infection, Postoperative Wound, Postoperative Wound Infection, Infections, Nosocomial, Management Practices
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
5,158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
9
States / cities
Atlanta, Georgia • Bethesda, Maryland • New York, New York + 6 more
Withdrawn Not applicable Interventional Accepts healthy volunteers

Reconstruction Flaps for Nasal Surgical Wounds RCT

NCT04729231
Conditions
Surgical Wound
Interventions
Nasalis Sling Flap, Lobed Transposition Flap
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
19 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Chicago, Illinois