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ClinicalTrials.gov public records Last synced Oct 17, 2026, 5:20 AM EDT

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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Incisional Hernia of Anterior Abdominal Wall Clear all
Not yet recruiting Not applicable Interventional

The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

NCT07145099
View directory record Official record
Conditions
Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
Interventions
PT Group, Usual Care
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 17, 2026, 5:20 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure

NCT06575166
View directory record Official record
Conditions
Ventral Hernia, Incisional Hernia, Parastomal Hernia
Interventions
Abdominal wall tension, Intra-abdominal pressure
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 17, 2026, 5:20 AM EDT
Terminated No phase listed Observational

Incisional Hernia Outcomes Study Using Parietex Composite Mesh

NCT00459602
View directory record Official record
Conditions
Incisional Hernia
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 26, 2015 · Synced Oct 17, 2026, 5:20 AM EDT
Terminated No phase listed Observational

Prevena Incision Management System Wound Care

NCT02953769
View directory record Official record
Conditions
Ventral Hernia
Interventions
Not listed
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 89 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Celebration, Florida
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 17, 2026, 5:20 AM EDT
Recruiting Phase 4 Interventional

Preoperative BOTOX® Injection for Large Ventral Hernia Repair

NCT07220382
View directory record Official record
Conditions
Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome, Hernia Surgery, Hernia, Hernia Incisional
Interventions
OnabotulinumtoxinA Injection, Saline (placebo) Injection, OnabotulinumtoxinA, 0.9 % Normal Saline, Open Ventral Hernia Repair
Procedure · Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 17, 2026, 5:20 AM EDT
Completed Not applicable Interventional Results available

A Prospective, Multicenter All Comers Study of Phasix Mesh for Ventral or Incisional Hernia Repair

NCT02053168
View directory record Official record
Conditions
Ventral Hernia, Incisional Hernia
Interventions
Resorbable Mesh
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
6
States / cities
Beverly Hills, California • Los Angeles, California • Celebration, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 17, 2026, 5:20 AM EDT
Completed Not applicable Interventional

A Study to Compare Ventral Incisional Hernia by Laparoscopic vs Open Repair With Mesh

NCT00240188
View directory record Official record
Conditions
Hernia, Ventral
Interventions
Open mesh repair of ventral incisional hernia, Laparoscopic mesh repair of ventral incisional hernia
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2010 · Synced Oct 17, 2026, 5:20 AM EDT
Not yet recruiting Not applicable Interventional

Phasix Mesh Underlay During Loop Ileostomy Closure

NCT07871630
View directory record Official record
Conditions
Incisional Hernia of Anterior Abdominal Wall
Interventions
Long-acting absorbable mesh
Device
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 17, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ultrasound Assessment of Ventral Hernia Defects

NCT03043079
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Ultrasound Acoustic Radiation Forced Impulse Shear Wave Velocity
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
20 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 17, 2026, 5:20 AM EDT
Terminated Not applicable Interventional Results available

Complex Ventral Hernia Repair Using Biologic or Synthetic Mesh

NCT02041494
View directory record Official record
Conditions
Hernia, Ventral
Interventions
Ventralight, Strattice
Device
Lead sponsor
Hobart Harris
Other
Eligibility
21 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Oct 17, 2026, 5:20 AM EDT
Terminated Not applicable Interventional

Gentrix™ Versus Biological or Prosthetic Mesh

NCT03034213
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Gentrix™ Surgical Matrix (Treatment), Permacol, Parietex, Progrip, Strattice Perforated, or Surgimend (Control)
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 17, 2026, 5:20 AM EDT
Not yet recruiting Not applicable Interventional

Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia Repair

NCT07874724
View directory record Official record
Conditions
Ventral Hernia, Incisional Hernia, Hernia, Hernia Abdominal Wall, Hernia Incisional, Hernia Incisional Ventral, Hernia of Abdominal Wall, Hernia Surgery
Interventions
Cryoneurolysis
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 17, 2026, 5:20 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparative Study of Biologic Mesh Versus Repair With Component Separation.

NCT01295125
View directory record Official record
Conditions
Ventral Hernia
Interventions
XenMATRIX mesh, Open abdominal ventral hernia repair
Device · Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 17, 2026, 5:20 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Shear-Wave Elastography

NCT06306976
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
Procedure · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 17, 2026, 5:20 AM EDT
Completed No phase listed Observational

Flexible Composite Next Generation Tissue Separating Mesh in Laparoscopic Incisional/Ventral Hernia Repair

NCT01162564
View directory record Official record
Conditions
Incisional Hernia, Ventral Hernia
Interventions
NG-TSM
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
6
States / cities
Jefferson City, Missouri • St Louis, Missouri • The Bronx, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2011 · Synced Oct 17, 2026, 5:20 AM EDT
Completed Not applicable Interventional

Watchful Waiting of Incisional Hernias

NCT00351455
View directory record Official record
Conditions
Incisional Hernia, Ventral Hernia, Umbilical Hernia
Interventions
smoking cessation, tighter diabetic control, diet and exercise program
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 17, 2026, 5:20 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Surgisis Gold Graft for Incision Reinforcement After Open Bariatric Surgery

NCT00274625
View directory record Official record
Conditions
Hernia, Obesity
Interventions
Surgisis Gold Graft, Control
Device · Procedure
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
2
States / cities
Rochester, Minnesota • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 12, 2014 · Synced Oct 17, 2026, 5:20 AM EDT
Recruiting Not applicable Interventional

GORE® ENFORM Biomaterial Product Study

NCT04718168
View directory record Official record
Conditions
Hernia, Ventral, Hernia, Hiatal, Hernia, Diaphragmatic, Incisional Hernia
Interventions
Gore ENFORM Biomaterial (Preperitoneal), Gore ENFORM Biomaterial (Intraperitoneal)
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
9
States / cities
San Diego, California • Denver, Colorado • Sarasota, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 17, 2026, 5:20 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?

NCT02007096
View directory record Official record
Conditions
Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications, Pain, Postoperative
Interventions
Transabdominal Plane Block, Non Transabdominal Plane Block
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 19, 2018 · Synced Oct 17, 2026, 5:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Tension in Posterior Component Separation for Abdominal Wall Reconstruction

NCT05142761
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Not listed
Lead sponsor
Michael Rosen
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 17, 2026, 5:20 AM EDT
Terminated No phase listed Observational

Observational Biologic or Prosthetic Mesh

NCT03317665
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Mesh for hernia repair
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Oct 17, 2026, 5:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh

NCT06409091
View directory record Official record
Conditions
Hernia, Ventral, Hernia Incisional
Interventions
Medium weight or Heavy weight mesh
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,496 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 17, 2026, 5:20 AM EDT
Completed No phase listed Observational

Observational Study to Evaluate Ventral Incisional Hernia Repair Using a Biologic Mesh (Cook Biodesign)

NCT02129140
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
Hernia graft/mesh
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 17, 2026, 5:20 AM EDT
Completed Not applicable Interventional Results available

A Prospective Trial of a Bio-absorbable Mesh in Challenging Laparoscopic Ventral or Incisional Hernia Repair

NCT02712398
View directory record Official record
Conditions
Hernia, Ventral, Incisional Hernia
Interventions
Phasix™ ST
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
16
States / cities
New Haven, Connecticut • Celebration, Florida • Atlanta, Georgia + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2021 · Synced Oct 17, 2026, 5:20 AM EDT