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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Incisional Negative Pressure Wound Therapy Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial

NCT03010137
View directory record Official record
Conditions
Complications Wounds, Negative Pressure Wound Therapy, Wound Healing Delayed, Incisional, Panniculectomy, Incisional Negative Pressure Wound Therapy, Incisional Vac, Wound Vac, Obese, Renal Failure, Kidney Transplant; Complications, Wound Healing Complication
Interventions
Incisional Negative Pressure Wound Therapy, Standard Closure with Skin Glue, PICO (Smith&Nephew), Dermabond
Procedure · Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Phase 4 Interventional Results available

A Randomized Clinical Trial Evaluating Negative Pressure Therapy to Decrease Vascular Groin Incision Complications

NCT02581904
View directory record Official record
Conditions
Wound Infection, Peripheral Arterial Disease, Aneurysm, Surgical Wound Dehiscence
Interventions
Prevena Care, Dry gauze dressing care
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 100 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 23, 2026, 11:14 AM EDT
Recruiting Not applicable Interventional

Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery

NCT04003038
View directory record Official record
Conditions
Body Mass Index Greater Than or Equal to 30, Malignant Breast Neoplasm, Mammoplasty Patient, Obesity
Interventions
Negative Pressure Wound Therapy, Wound Care Management
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Not applicable Interventional Results available

Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds

NCT02638298
View directory record Official record
Conditions
Sarcoma, Cancer, Infectious Disease
Interventions
Prevana Dressing, Standard Dry Gauze Dressing
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Not applicable Interventional Results available

Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery

NCT02509260
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Prevena wound management system, Standard wound dressings
Device · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 23, 2026, 11:14 AM EDT
Terminated Not applicable Interventional Results available

Incisional Negative Pressure Wound Therapy

NCT01759381
View directory record Official record
Conditions
Spinal Deformity
Interventions
Negative pressure wound therapy (NPWT)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2015 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Not applicable Interventional Results available

PICO Breast Reduction Clinical Study Looking at Incision Healing Complications

NCT01640366
View directory record Official record
Conditions
Delayed Healing
Interventions
PICO
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Chicago, Illinois • The Bronx, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Sep 23, 2026, 11:14 AM EDT
Withdrawn Not applicable Interventional

Incisional Negative Pressure Dressing on Clean Closed Groin Incisions

NCT02006511
View directory record Official record
Conditions
Complication of Surgical Procedure
Interventions
Incisional Neg Pressure Wound Therapy (Prevena™), Standard of Care wound therapy
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Not applicable Interventional Results available

Closed Incision Negative Pressure Therapy vs Standard of Care

NCT03061903
View directory record Official record
Conditions
Wound Complication
Interventions
Prevena, Aquacel
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 23, 2026, 11:14 AM EDT
Recruiting Not applicable Interventional

NPWT Reduction Mammaplasty

NCT06725459
View directory record Official record
Conditions
Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty, Wound Healing
Interventions
Prophylactic ciNPWT, Standard Adhesive Dressing
Device · Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Phase 4 Interventional Results available

Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions

NCT02137447
View directory record Official record
Conditions
High Risk Abdominal Wounds
Interventions
Negative Pressure treatment
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 95 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 23, 2026, 11:14 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Prospective Observation of Wound Healing With Prevena Incision Management System

NCT01704924
View directory record Official record
Conditions
Scarring
Interventions
Prevena, Standard of Care Dressing
Device · Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Sep 23, 2026, 11:14 AM EDT
Not listed Not applicable Interventional

WoundVac in Obese Patients Undergoing Lumbar Surgery

NCT03688438
View directory record Official record
Conditions
Obesity, Lumbar Spine Surgery
Interventions
Closed-Incision Negative-Pressure Therapy
Device
Lead sponsor
Norton Leatherman Spine Center
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Sep 23, 2026, 11:14 AM EDT
Terminated Not applicable Interventional Results available

Surgical Application of Vac Dressings In Obese Patients to Reduce Wound Complications

NCT02461433
View directory record Official record
Conditions
Wound Infection, Surgical, Obesity, Postoperative Complications
Interventions
Prevena, Standard Dressing
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Prevena Spine for Use in Spine Surgery

NCT05555355
View directory record Official record
Conditions
Surgery, Incision, Surgical
Interventions
Prevena Plus 125 Therapy Unit, Spine surgery
Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 23, 2026, 11:14 AM EDT
Terminated Not applicable Interventional Results available

Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA

NCT04712019
View directory record Official record
Conditions
Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases, Musculoskeletal Diseases, Edema Leg, Joint Pain, Arthritis Knee
Interventions
Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
6
States / cities
Annapolis, Maryland • Baltimore, Maryland • Columbia, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 23, 2026, 11:14 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Prophylactic Post-Cesarean Incisional Negative-pressure Wound Therapy in Morbidly Obese Patients

NCT02901613
View directory record Official record
Conditions
Negative-pressure Wound Therapy, Morbid Obesity, Cesarean Section, Wound Infection
Interventions
Negative-pressure wound therapy
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older · Female only
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2017 · Synced Sep 23, 2026, 11:14 AM EDT
Terminated Not applicable Interventional Results available

Closed Incision Negative Pressure Wound Therapy vs. Foam as Post Operative Dressing

NCT05427916
View directory record Official record
Conditions
Diabetes, Morbid Obesity, Lymphedema, Orthopedic Disorder
Interventions
Avance Solo, Optifoam
Device · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 23, 2026, 11:14 AM EDT
Recruiting Phase 3 Interventional

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

NCT06337292
View directory record Official record
Conditions
Fracture of Tibia, Wound Heal, Infected Wound, Wound Complication, Wound Dehiscence
Interventions
Incisional Negative Pressure Wound Therapy (NPWT)
Device
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Baltimore, Maryland • Lebanon, New Hampshire • Nashville, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Not applicable Interventional Results available

Evaluating Advantages of Prevena After Hip and Knee Arthroplasty

NCT01854138
View directory record Official record
Conditions
Infection of Total Hip Joint Prosthesis
Interventions
Prevena Incision Management System
Device
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Sep 23, 2026, 11:14 AM EDT
Completed Phase 4 Interventional Results available

The Invia Motion at Cesarean Study

NCT04365452
View directory record Official record
Conditions
Negative Pressure Wound Therapy, Cesarean Section; Infection
Interventions
Invia Motion
Device
Lead sponsor
Indiana University
Other
Eligibility
Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Sep 23, 2026, 11:14 AM EDT
Not listed Not applicable Interventional

A Prospective, Randomized, Comparative Study to Assess the Prevention of Surgical Site Infection (SSI's) in Revision Total Joint Arthroplasty Patients Treated With Single-Use Negative Pressure Wound Therapy (PICO) or Standard Care Dressings (AQUACEL Ag SURGICAL Dressing).

NCT03180346
View directory record Official record
Conditions
Surgical Incision
Interventions
PICO, Aquacel
Device
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 7, 2017 · Synced Sep 23, 2026, 11:14 AM EDT
Withdrawn Not applicable Interventional

VAC NPWT KCI Dressing Study

NCT01366105
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
V.A.C. by K.C.I.
Device
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 23, 2026, 11:14 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems

NCT03716050
View directory record Official record
Conditions
Perfusion; Complications
Interventions
Nitroglycerin, Negative Pressure Wound Therapy/ Wound VAC, Fluorescent Angiography with indocyanine-green (not to exceed 5mg/kg), No treatment
Drug · Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Sep 23, 2026, 11:14 AM EDT