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ClinicalTrials.gov public records Last synced Jun 11, 2026, 12:48 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Incomplete Spinal Cord Injury Clear all
Recruiting No phase listed Observational

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

NCT06998134
View directory record Official record
Conditions
Muscle Weakness, Problems Moving Their Arms and Legs
Interventions
Extension assist knee ankle foot orthosis (EA-KAFO)
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years to 25 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Jun 11, 2026, 12:48 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Examining the Effect of Acute Intermittent Hypoxia on Serum Blood Proteins and Lower Limb Function

NCT06906536
View directory record Official record
Conditions
INCOMPLETE SPINAL CORD INJURY (ASIA D), Able Bodied
Interventions
Acute Intermittent Hypoxia (AIH)
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Jun 11, 2026, 12:48 AM EDT
Active, not recruiting No phase listed Observational

Incomplete Cervical SCI Without Instability

NCT05653206
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Nonsurgical treatment, Surgical treatment
Procedure
Lead sponsor
AO Foundation, AO Spine
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
San Francisco, California • Baltimore, Maryland • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jun 11, 2026, 12:48 AM EDT
Active, not recruiting Not applicable Interventional

Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury

NCT02274116
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
SHAM - Intermittent Room Air - room air mixture, AIH - Intermittent Hypoxia - hypoxia air mixture
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Jun 11, 2026, 12:48 AM EDT
Not listed Not applicable Interventional

Activity Dependent Rehabilitation Model to Improve Bone and Muscle Outcomes

NCT02309983
View directory record Official record
Conditions
Disuse Osteoporosis, Atrophy, Disuse, Nervous System, Structural; Marker, Skeletal Muscle Hypertrophy
Interventions
Electrical Stimulation, Stand Retraining with Body Weight Support (BWS)
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 58 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Jun 11, 2026, 12:48 AM EDT
Recruiting Not applicable Interventional

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

NCT05726591
View directory record Official record
Conditions
Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
Interventions
EA-KAFO
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
3 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Jun 11, 2026, 12:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training

NCT03057652
View directory record Official record
Conditions
Complete Spinal Cord Injury, Incomplete Spinal Cord Injury, Acquired Brain Injury, Multiple Sclerosis
Interventions
ReWalk, EKSO, REX
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2022 · Synced Jun 11, 2026, 12:48 AM EDT
Completed Not applicable Interventional Results available

Effects of Robotic Versus Manually-Assisted Locomotor Training for Individuals With Incomplete Spinal Cord Injury

NCT00127439
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Manually Assisted Locomotor Training, Robotic Assisted Locomotor Training
Procedure · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Jun 11, 2026, 12:48 AM EDT
Recruiting Not applicable Interventional

Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury

NCT02329652
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Spinal Cord Injury Cervical, Spinal Cord Injury at C5-C7 Level With Complete Lesion, Spinal Cord Injury at C5-C7 Level With Incomplete Lesion
Interventions
Networked Neuroprosthetic System for Grasp and Trunk
Device
Lead sponsor
Anne Bryden
Other
Eligibility
17 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2031
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jun 11, 2026, 12:48 AM EDT
Completed Not applicable Interventional Results available

Comparison of Lokomat and Aquatic Exercise for Individuals With Chronic Incomplete Spinal Cord Injury

NCT01407354
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Lokomat treadmill training, Aquatic exercise therapy
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Atlanta, Georgia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Jun 11, 2026, 12:48 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Spinal Cord Injury Leg Rehabilitation

NCT01498991
View directory record Official record
Conditions
Spinal Cord Injury, Paraplegia, Quadriplegia, Tetraplegia
Interventions
AMES Treatment
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Atlanta, Georgia • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Jun 11, 2026, 12:48 AM EDT
Terminated Phase 4 Interventional

The Efficacy of Denosumab in Incomplete Patients Spinal Cord Injury

NCT03029442
View directory record Official record
Conditions
Secondary Osteoporosis, Spinal Cord Injury
Interventions
Denosumab (Prolia), Placebo (normal saline)
Drug · Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Jun 11, 2026, 12:48 AM EDT
Completed Not applicable Interventional

Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders

NCT01961557
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
Interventions
EA-KAFO
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 11, 2026, 12:48 AM EDT
Completed Not applicable Interventional Results available

A Telerehabilitation Program for SCI

NCT04977037
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 19, 2025 · Synced Jun 11, 2026, 12:48 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury

NCT01683838
View directory record Official record
Conditions
Spinal Cord Injury, Muscle Spasticity
Interventions
Fampridine-SR, Placebo
Drug
Lead sponsor
Acorda Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
27
States / cities
Birmingham, Alabama • Long Beach, California • Sacramento, California + 23 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Jun 11, 2026, 12:48 AM EDT
Not yet recruiting Not applicable Interventional

Vibrotactile Coordinated Reset for Spasticity After Spinal Cord Injury

NCT06290609
View directory record Official record
Conditions
Spasticity, Muscle, Spinal Cord Injuries
Interventions
Vibrotactile Coordinated Reset
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Jun 11, 2026, 12:48 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

A Novel System for Quasi Real-Time Tracking of Neuromuscular Responses During NMES

NCT05243576
View directory record Official record
Conditions
Spinal Cord Injuries, Incomplete Spinal Cord Injury
Interventions
Not listed
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Jun 11, 2026, 12:48 AM EDT
Completed Not applicable Interventional Results available

Effects of Transcutaneous Spinal Direct Current Stimulation in Incomplete Spinal Cord Injury

NCT03249454
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
Anodal tsDCS, Cathodal tsDCS, Sham tsDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Jun 11, 2026, 12:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Modeling, Optimization, and Control Methods for a Personalized Hybrid Walking Exoskeleton

NCT04453943
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Paraplegia, Incomplete
Interventions
Exoskeleton Walking - with or without FES, Exoskeleton Sitting to Standing - with or without FES
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Jun 11, 2026, 12:48 AM EDT
Recruiting Not applicable Interventional

Safety and Feasibility of Paired Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Upper Limb Rehabilitation in Incomplete Spinal Cord Injury

NCT06543277
View directory record Official record
Conditions
Chronic Incomplete Cervical Spinal Cord Injury (SCI)
Interventions
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Jun 11, 2026, 12:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Acute Intermittent Hypoxia on Motor Learning

NCT05341466
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
Acute Intermittent Hypoxia, SHAM Acute Intermittent Hypoxia
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Jun 11, 2026, 12:48 AM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Self-Management Program for AIS D SCI

NCT05800717
View directory record Official record
Conditions
Psychological Well-Being, Spinal Cord Injuries
Interventions
SCI Self-Management for AIS D
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jun 11, 2026, 12:48 AM EDT
Completed Not applicable Interventional Results available

Robotically Assisted Treadmill Training in Spinal Cord Injury (SCI)

NCT00385918
View directory record Official record
Conditions
Paraplegia, Quadriplegia, Spinal Cord Injury, Tetraplegia
Interventions
Lokomat Training, Home stretching then Lokomat training
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2014 · Synced Jun 11, 2026, 12:48 AM EDT
Enrolling by invitation No phase listed Observational

Blood Flow-restricted Resistance Exercise to Promote Muscle Strength and Use in Adults With Incomplete Spinal Cord Injury

NCT06907381
View directory record Official record
Conditions
Spinal Cord Injury Cervical
Interventions
Blood flow-restricted resistance exercise
Behavioral
Lead sponsor
Quality Living, Inc.
Other
Eligibility
19 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jun 11, 2026, 12:48 AM EDT