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Showing 1–24 of 207 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Incontinence, Urinary Stress Clear all
Completed Phase 2 Interventional

Biomechanical Effects of Duloxetine on Bladder and Sphincter Muscle Function in Women in Pure Genuine Stress Incontinence

NCT00190567
View directory record Official record
Conditions
Urinary Stress Incontinence
Interventions
duloxetine, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 25, 2007 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional

A Clinical Evaluation of the Tension-Free Vaginal Tape Obturator System For Treatment of Stress Urinary Incontinence (Urinary Leakage)

NCT00196521
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
Tension-free vaginal tape obturator system
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
11
States / cities
Denver, Colorado • Norwalk, Connecticut • Louisville, Kentucky + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2007 · Synced Sep 9, 2026, 8:30 AM EDT
Not yet recruiting Phase 4 Interventional

Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery

NCT07600697
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
Interventions
Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Patient-Centered Versus Physician-Centered Counseling MidUrethral Sling Videos

NCT03198481
View directory record Official record
Conditions
Stress Urinary Incontinence, Satisfaction
Interventions
Patient-Centered Counseling Video, Physician Counseling Video
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Albuquerque, New Mexico • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 9, 2026, 8:30 AM EDT
Recruiting Not applicable Interventional

Sequence of Midurethral Sling Placement During Robotic Sacrocolpopexy

NCT07008898
View directory record Official record
Conditions
Stress Incontinence Female, Pelvic Organ Prolapse
Interventions
Midurethral sling placed before robotic sacrocolpopexy, Midurethral sling placed after robotic sacrocolpopexy
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama • Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effect of an Additional Stress Incontinence Procedure on Overactive Bladder During Pelvic Organ Prolapse Repair

NCT02502838
View directory record Official record
Conditions
Overactive Bladder, Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
22 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Voiding Trials After Midurethral Sling for Stress Incontinence

NCT02400034
View directory record Official record
Conditions
Stress Urinary Incontinence, Urethral Hypermobility, Cystocele
Interventions
Voiding trial
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Oct 20, 2016 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 2 Interventional

Efficacy and Safety of Duloxetine, Placebo and Pelvic Floor Muscle Training in Subjects With Stress Urinary Incontinence

NCT00190606
View directory record Official record
Conditions
Urinary Stress Incontinence
Interventions
Duloxetine, Pelvic Floor Muscle Training (PFMT), Imitation PFMT, placebo
Drug · Procedure
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Jan 25, 2007 · Synced Sep 9, 2026, 8:30 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Urinary Catheter Self-Discontinuation After Urogynecology Surgery

NCT05860634
View directory record Official record
Conditions
Urinary Retention, Pelvic Organ Prolapse, Stress Urinary Incontinence, Catheter Related Complication
Interventions
Catheter self-discontinuation
Procedure
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
4
States / cities
Austin, Texas • Kyle, Texas • Round Rock, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional

Pelvital Stress Urinary Incontinence Training Device: P-SUIT

NCT02954042
View directory record Official record
Conditions
Incontinence
Interventions
Pelvital probe, Placebo Probe
Device
Lead sponsor
Pelvital USA, Inc.
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
4
States / cities
Maple Grove, Minnesota • Maplewood, Minnesota • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 3 Interventional Results available

ATLAS: Ambulatory Treatments for Leakage Associated With Stress

NCT00270998
View directory record Official record
Conditions
Stress Urinary Incontinence, Urinary Incontinence
Interventions
Behavioral Therapy, Intravaginal Pessary, Pessary combined with behavioral therapy
Behavioral · Device
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
445 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Maywood, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated May 29, 2018 · Synced Sep 9, 2026, 8:30 AM EDT
Active, not recruiting Not applicable Interventional

Perineal Massage for Pessary Examinations

NCT06416982
View directory record Official record
Conditions
Prolapse, Vaginal, Stress Urinary Incontinence, Pessaries, Pain
Interventions
Perineal massage
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Lidocaine for Pessary Check Pain Reduction

NCT05493735
View directory record Official record
Conditions
Pelvic Organ Prolapse, Stress Urinary Incontinence
Interventions
Lidocaine Hcl 2% Jelly, Placebo Jelly
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Sep 9, 2026, 8:30 AM EDT
Active, not recruiting Phase 3 Interventional

Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence

NCT03104517
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
AMDC-USR (iltamiocel), Placebo
Biological · Other
Lead sponsor
Cook MyoSite
Industry
Eligibility
18 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
20
States / cities
Tucson, Arizona • La Mesa, California • Los Angeles, California + 17 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Functional Assessment and Muscle Evaluation Through Exercise Trial

NCT03166150
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Multi-modal rehabilitation program, Pelvic Floor Physical therapy
Other
Lead sponsor
Howard University
Other
Eligibility
65 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 9, 2026, 8:30 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Single-incision Sling vs Urethral Bulking During Prolapse Surgery for Occult Stress Incontinence

NCT05210738
View directory record Official record
Conditions
Stress Incontinence, Female
Interventions
Single incision sling, Bulkamid bulking agent
Device · Drug
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 2 Interventional Results available

Study to Assess Enobosarm (GTx-024) in Postmenopausal Women With Stress Urinary Incontinence

NCT03241342
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
GTx 024, Placebo
Drug
Lead sponsor
GTx
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
491 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
62
States / cities
Homewood, Alabama • Mobile, Alabama • Anchorage, Alaska + 57 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 3 Interventional

Study Comparing Tension-free Vaginal Tape With the Monarc Procedure for Stress Urinary Incontinence

NCT00475839
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
Tension-free Vaginal Tape, Monarc sub-fascial hammock
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
3
States / cities
Baltimore, Maryland • Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2013 · Synced Sep 9, 2026, 8:30 AM EDT
Recruiting Not applicable Interventional

BTL Emsella Chair Versus Sham for the Treatment of Stress Urinary Incontinence

NCT04133675
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
BTL Emsella, Sham BTL Emsella
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Emsella for Reducing tSUI After HOLEP

NCT07580404
View directory record Official record
Conditions
Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms, Enlarged Prostate (BPH)
Interventions
Emsella chair
Device
Lead sponsor
Northwestern University
Other
Eligibility
50 Years to 80 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Autologous Cell Therapy for Stress Urinary Incontinence in Males Following Prostate Surgery

NCT02291432
View directory record Official record
Conditions
Urinary Incontinence, Stress, Urination Disorders, Urologic Diseases, Lower Urinary Tract Symptoms, Urological Manifestations
Interventions
autologous muscle-derived cells (AMDC)
Biological
Lead sponsor
Cook MyoSite
Industry
Eligibility
18 Years and older · Male only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
5
States / cities
Miami, Florida • Atlanta, Georgia • Royal Oak, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 9, 2026, 8:30 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fat Grafting Technique Using Autologous Adipose Tissue Lipogems in Patients Suffering From Stress Urinary Incontinence

NCT03295253
View directory record Official record
Conditions
Urinary Incontinence,Stress
Interventions
Autologous adipose tissue harvesting/grafting using Lipogems
Procedure
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 26, 2017 · Synced Sep 9, 2026, 8:30 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Practice-Based Intervention To Improve Care for a Diverse Population Of Women With Urinary Incontinence

NCT05534412
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Academic Detailing, Electronic Clinical Decision Support, APP Co-management, Electronic Referral
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
1,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
4
States / cities
La Jolla, California • Los Angeles, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed No phase listed Observational

The Effect of Mid-urethral Sling on the Urethral Dynamic Shape and Motion

NCT04843995
View directory record Official record
Conditions
Stress Urinary Incontinence
Interventions
Mid-urethral sling
Procedure
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years and older · Female only
Enrollment
190 participants
Timeline
2012 – 2021
U.S. locations
1
States / cities
Skokie, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Sep 9, 2026, 8:30 AM EDT