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ClinicalTrials.gov public records Last synced Oct 4, 2026, 6:33 PM EDT

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Showing 49–72 of 97 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Indocyanine Green Clear all
Recruiting Phase 1 Interventional

ICG Fluorescence in Knee Arthroscopy Study

NCT07793266
View directory record Official record
Conditions
To Assess the Feasibility, Visualization Capability, and Optimal Dosing of ICG Fluorescence Imaging for Intraoperative Assessment of Knee Tissue Perfusion
Interventions
Intravenous administration of indocyanine green (SPY Agent Green) 2 mL of SPY Agent Green (5.0 mg dose), Intravenous administration of indocyanine green (SPY Agent Green) 3 mL of SPY Agent Green (7.5 mg dose), Intravenous administration of indocyanine green (SPY Agent Green) 4 mL of SPY Agent Green (10 mg dose), Intravenous administration of indocyanine green (SPY Agent Green)5 mL of SPY Agent Green (12.5 mg dose)
Combination Product
Lead sponsor
Henry Ford Health System
Other
Eligibility
14 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Indocyanine Green for Central Nervous System Tumors

NCT02710240
View directory record Official record
Conditions
Suspected Central Nervous System Tumors
Interventions
Indocyanine Green (ICG), Intraoperative near-infrared (NIR)
Drug · Radiation
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Oct 4, 2026, 6:33 PM EDT
Not listed Not applicable Interventional

Improved Method of Detecting Cancer Metastases

NCT02368067
View directory record Official record
Conditions
Endometrial Carcinoma
Interventions
Standard of Care Sentinal Node Dye, Study Sentinal Node Dye
Procedure
Lead sponsor
Southeastern Regional Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Newnan, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 20, 2015 · Synced Oct 4, 2026, 6:33 PM EDT
Recruiting Phase 1 Interventional

Imaging of Lymphatic Vessels in People With Rheumatoid Arthritis (RA)

NCT05197530
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Indocyanine green, MultiSpectral Imaging System
Drug · Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Phase 1 Interventional

Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque

NCT01873716
View directory record Official record
Conditions
Atherosclerosis, Atherosclerotic Plaque, Carotid Stenosis
Interventions
Indocyanine green
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

NIR Fluorescence Imaging of Lymphatic Transport Using ICG

NCT02680067
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Indocyanine Green, MultiSpectral Imaging System
Drug · Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Phase 1 Interventional

Intraoperative Imaging of Thoracic Malignancies With Indocyanine Green

NCT01335893
View directory record Official record
Conditions
Lung Neoplasms
Interventions
Indocyanine Green
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 4, 2026, 6:33 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures

NCT01693484
View directory record Official record
Conditions
Fractures, Comminuted, Surgical Wound Dehiscence, Necrosis
Interventions
ICG (Indocyanine Green)
Drug
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 4, 2026, 6:33 PM EDT
Withdrawn Phase 4 Interventional

Evaluation of Neuroma Perfusion with Indocyanine Green Fluorescence Angiography

NCT06164392
View directory record Official record
Conditions
Neuroma, Neuroma Amputation, Neuroma of Upper Limb, Neuroma of Lower Limb
Interventions
Indocyanine green
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 1, 2025 · Synced Oct 4, 2026, 6:33 PM EDT
Recruiting Not applicable Interventional

Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

NCT07234968
View directory record Official record
Conditions
Bladder Cancer, Muscle-Invasive Bladder Carcinoma, Urothelial Carcinoma, Pelvic Malignancy, Bladder Transitional Cell Carcinoma, Bladder Neoplasm
Interventions
Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging
Procedure · Diagnostic Test
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 4, 2026, 6:33 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

SPY Fluorescence Imaging Systems and Indocyanine Green to Determine the Percentage of Successful Critical Anatomy Recognition in Laparoscopic Cholecystectomy Surgeries.

NCT05006950
View directory record Official record
Conditions
Cholecystitis
Interventions
Stryker1688 Fluorescence imaging system
Device
Lead sponsor
Stryker Endoscopy
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Annapolis, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 4, 2026, 6:33 PM EDT
Not yet recruiting No phase listed Observational

SLN Mapping and ICG Dye for Vulvar Cancer

NCT06035068
View directory record Official record
Conditions
Vulva Cancer
Interventions
Indocyanine green
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 4, 2026, 6:33 PM EDT
Active, not recruiting Not applicable Interventional

Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions

NCT02802553
View directory record Official record
Conditions
Invasive Breast Cancer
Interventions
Smart Goggle, Cardio-Green, SPY Elite Imaging system, Quest near-infrared (NIR) Imaging system, PDE Imaging system, Gamma probe, Blue Dyes
Device · Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Not applicable Interventional

Indocyanine Green and Near-infrared Fluorescence Imaging to Detect Sentinel Lymph Nodes in Patients With Endometrial Cancer

NCT02131558
View directory record Official record
Conditions
Endometrial Cancer, Sentinel Lymph Node Detection
Interventions
ICG Dye
Procedure
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 4, 2026, 6:33 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis

NCT07250854
View directory record Official record
Conditions
Biliary Atresia, Kasai, Cholestasis in Newborn, Cholestasis in Newborn Infant
Interventions
Indocyanine Green
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
2 Weeks to 4 Months
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 4, 2026, 6:33 PM EDT
Active, not recruiting Phase 1 Interventional

Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship

NCT05937269
View directory record Official record
Conditions
Lymphedema of Face, Head and Neck Cancer
Interventions
Near-infrared fluorescence lymphatic imaging, advanced pneumatic compression therapy
Combination Product · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 4, 2026, 6:33 PM EDT
Not listed No phase listed Observational

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

NCT04492735
View directory record Official record
Conditions
Metastatic Disease, Primary Tumor, Solid Malignancies
Interventions
Not listed
Lead sponsor
Roshni Dasgupta
Other
Eligibility
1 Day to 45 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 4, 2026, 6:33 PM EDT
Recruiting Not applicable Interventional

Robotic Adrenalectomy With Versus Without Indocyanine Green Fluorescence Imaging

NCT07813247
View directory record Official record
Conditions
Adrenalectomy
Interventions
indocyanine green imaging
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 4, 2026, 6:33 PM EDT
Enrolling by invitation Phase 1Phase 2 Interventional

Evaluation of Lymphatic Response to Physiotherapy in Patients With Swelling Associated With Superficial Venous Disease

NCT07165340
View directory record Official record
Conditions
Chronic Venous Disease
Interventions
Indocyanine Green near infrared fluorescence imaging, advanced pneumatic compression, Duplex ultrasound, compression wrap
Combination Product · Device · Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Phase 1 Interventional

Nuclear and Near-Infrared (NIR) Imaging in Melanoma

NCT01295931
View directory record Official record
Conditions
Melanoma
Interventions
Indocyanine Green (IC-Green), Imaging
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Oct 4, 2026, 6:33 PM EDT
Completed No phase listed Observational Results available

ICG 24h Prior to Operative Treatment of Orthopaedic Infection

NCT04927637
View directory record Official record
Conditions
Trauma Injury, Bone Infection
Interventions
imaging 24 hours following intravenous administration of ICG
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Not applicable Interventional Results available

Infrared Lymphangiography as a Method of Sentinel Node Identification

NCT02057393
View directory record Official record
Conditions
Melanoma, Sentinel Node
Interventions
Indocyanine green, Technetium99, Methylene blue
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2017 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Not applicable Interventional Results available

Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract

NCT01112514
View directory record Official record
Conditions
High Risk Polyposis Syndrome, Distal Colonic Lesions, Colorectal Polyps
Interventions
indocyanine green
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2014 · Synced Oct 4, 2026, 6:33 PM EDT
Completed Phase 1 Interventional

Diffuse Optical Imaging With Indocyanine Green Solution in Imaging Pelvic Lymph Nodes in Patients With Stage II Prostate Cancer Undergoing Surgery

NCT02119858
View directory record Official record
Conditions
Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
Interventions
indocyanine green solution, diffuse optical imaging, robot-assisted laparoscopic surgery, therapeutic lymphadenectomy
Drug · Other · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 4, 2026, 6:33 PM EDT