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ClinicalTrials.gov public records Last synced Oct 15, 2026, 4:48 PM EDT

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Showing 529–552 of 850 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Infant, Premature Clear all
Active, not recruiting Not applicable Interventional

Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial).

NCT04372953
View directory record Official record
Conditions
Lung Injury, Preterm Birth
Interventions
Positive End-Expiratory Pressure (PEEP)
Procedure
Lead sponsor
Murdoch Childrens Research Institute
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
906 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
4
States / cities
Little Rock, Arkansas • San Diego, California • Indianapolis, Indiana + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 15, 2026, 4:48 PM EDT
Withdrawn Not applicable Interventional

Microbiome Survey of Preterm Infants

NCT01942577
View directory record Official record
Conditions
Skin Microbiome
Interventions
NoSting
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Oct 15, 2026, 4:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preemie Prep For Parents (P3): Home Antenatal Prematurity Education

NCT04093492
View directory record Official record
Conditions
Premature Birth, Decision Making, Prenatal Care, Resuscitation, Infant, Premature
Interventions
Preemie Prep for Parents (P3) Outpatient Mobile Intervention, ACOG links
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Not listed
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 15, 2026, 4:48 PM EDT
Terminated Phase 4 Interventional Results available

Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants

NCT00767039
View directory record Official record
Conditions
Prematurity, Respiratory Distress Syndrome, Patent Ductus Arteriosus
Interventions
Survanta (beractant), Curosurf (poractant)
Drug
Lead sponsor
Alan Fujii
Other
Eligibility
Up to 8 Hours
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 3, 2011 · Synced Oct 15, 2026, 4:48 PM EDT
Completed Not applicable Interventional Results available

GPS (Giving Parents Support): Parent Navigation After NICU Discharge

NCT02643472
View directory record Official record
Conditions
Premature Birth of Newborn, Family, Immature Newborn, Newborn Morbidity, Infant Newborn Disease
Interventions
Parent Navigator, Care Notebook
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 15, 2026, 4:48 PM EDT
Completed No phase listed Observational

Splanchnic Tissue Oxygenation During Enteral Feedings in Anemic Premature Infants at Risk for Necrotizing Enterocolitis

NCT01735578
View directory record Official record
Conditions
Anemia of Prematurity, Necrotizing Enterocolitis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 12 Weeks
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 5, 2015 · Synced Oct 15, 2026, 4:48 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Invictus Medical, Medical Cranial Support Device (CSD) is a Device Safety Study in Infants at Risk of Head Ulcers.

NCT02224859
View directory record Official record
Conditions
Other Preterm Infants
Interventions
HCP will place the Invictus Cranial Support Device (CSD) on the patient, human intervention
Device · Other
Lead sponsor
Invictus Medical, Inc.
Industry
Eligibility
30 Weeks to 36 Weeks
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2015 · Synced Oct 15, 2026, 4:48 PM EDT
Recruiting Not applicable Interventional

Brain Uptrain to Improve Learning and Development

NCT06638801
View directory record Official record
Conditions
Term Infant, Late Preterm Infant
Interventions
Coach-led caregiver-implemented early literacy and developmental programming, Reach Out and Read Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 7 Days
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 15, 2026, 4:48 PM EDT
Completed No phase listed Observational

Effective Fraction of Inspired Oxygen With Nasal Cannula in Premature Infants

NCT03431818
View directory record Official record
Conditions
Oxygen Therapy
Interventions
Nasal cannula flow rate
Other
Lead sponsor
University of Miami
Other
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 15, 2026, 4:48 PM EDT
Recruiting Not applicable Interventional

Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants

NCT06335524
View directory record Official record
Conditions
Child Development, Infant Development, Infant, Premature, Diseases
Interventions
Finger puppet, Bookworm reading intervention training and routine EDI care.
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Week to 17 Weeks
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 15, 2026, 4:48 PM EDT
Completed Not applicable Interventional

Kangaroo Care and Premature Infant Sleep

NCT02473055
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Kangaroo Care
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
7 Days to 37 Weeks
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2015 · Synced Oct 15, 2026, 4:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feeding Study in Premature Infants

NCT00681018
View directory record Official record
Conditions
Premature Infants
Interventions
Liquid human milk fortifier, Powder human milk fortifier
Other
Lead sponsor
Mead Johnson Nutrition
Industry
Eligibility
Up to 40 Days
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
14
States / cities
Little Rock, Arkansas • Jacksonville, Florida • Plantation, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2010 · Synced Oct 15, 2026, 4:48 PM EDT
Not yet recruiting Phase 2 Interventional

Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?

NCT07447739
View directory record Official record
Conditions
Respiratory Distress Syndrome (RDS), Bronchopulmonary Dysplasia (BPD)
Interventions
Betamethasone
Drug
Lead sponsor
Khang Nguyen
Other
Eligibility
Up to 28 Weeks
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 15, 2026, 4:48 PM EDT
Completed Phase 2Phase 3 Interventional Results available

A Study to Evaluate the Safety of MEDI8897 for the Prevention of Medically Attended Respiratory Syncytial Virus(RSV) Lower Respiratory Track Infection (LRTI) in High-risk Children

NCT03959488
View directory record Official record
Conditions
Respiratory Syncytial Virus Infections
Interventions
MEDI8897, Palivizumab
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
0 Years to 1 Year
Enrollment
925 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
30
States / cities
Anaheim, California • Long Beach, California • Los Angeles, California + 27 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 15, 2026, 4:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sleep in SNOO Smart Sleeper Bassinet in Preterm Infants

NCT05711927
View directory record Official record
Conditions
Prematurity, Very Preterm Maturity of Infant
Interventions
SNOO Smart Sleeper, Traditional bassinet
Device
Lead sponsor
Columbia University
Other
Eligibility
1 Week to 12 Weeks
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 15, 2026, 4:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants

NCT02691156
View directory record Official record
Conditions
Bilirubin-induced Neurologic Dysfunction, Hyperbilirubinemia, Kernicterus, Infant, Premature, Infant, Low Birth Weight
Interventions
Bilirubin Binding Capacity, End-tidal Carbon Monoxide, Carboxyhemoglobin
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
24 Weeks to 34 Weeks
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2021 · Synced Oct 15, 2026, 4:48 PM EDT
Terminated Not applicable Interventional Results available

Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants

NCT05030012
View directory record Official record
Conditions
Infant, Premature, Neonatal Respiratory Distress, Oxygen Saturation, Bronchopulmonary Dysplasia
Interventions
Automated Control, Manual Control
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Salt Lake City, Utah • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Oct 15, 2026, 4:48 PM EDT
Recruiting Not applicable Interventional

A Randomized Controlled Trial of Impact of Wearable, Wireless Breast Pumps on Frequency and Efficacy of Milk Expression in Mothers of Premature Infants

NCT06723067
View directory record Official record
Conditions
Premature Birth
Interventions
Wearable wireless breast pump
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Oct 15, 2026, 4:48 PM EDT
Withdrawn Phase 1 Interventional

Phase 1 Intravenous Citrulline for the Prevention of Bronchopulmonary Dysplasia in Preterm Infants

NCT00742534
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Intravenous L-Citrulline
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
2 Days to 14 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 30, 2011 · Synced Oct 15, 2026, 4:48 PM EDT
Completed Phase 1 Interventional

Early Blood Pressure Management in Extremely Premature Infants

NCT00874393
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Hypotension, Blood Pressure
Interventions
Dopamine, Hydrocortisone, Infusion Placebo, Syringe Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 24 Hours
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated May 25, 2017 · Synced Oct 15, 2026, 4:48 PM EDT
Completed No phase listed Observational

Premature Infant Exposure to Noise Generated by Respiratory Support

NCT01748214
View directory record Official record
Conditions
Premature Birth of Newborn
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
7 Days and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 12, 2012 · Synced Oct 15, 2026, 4:48 PM EDT
Completed No phase listed Observational

Cerebral Function Monitoring in Premature Infants

NCT00873847
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Electroencephalography
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 72 Hours
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
8
States / cities
Palo Alto, California • Atlanta, Georgia • Detroit, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2017 · Synced Oct 15, 2026, 4:48 PM EDT
Completed No phase listed Observational

Neurodevelopmental Outcomes and Fluconazole Prophylaxis

NCT00975949
View directory record Official record
Conditions
Neurodevelopmental Outcomes
Interventions
Survey
Other
Lead sponsor
University of Virginia
Other
Eligibility
7 Years to 10 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Oct 15, 2026, 4:48 PM EDT
Completed Not applicable Interventional Results available

Transfusion of Prematures Trial

NCT01702805
View directory record Official record
Conditions
Infant, Newborn, Diseases, Infant, Extremely Low Birth Weight, Infant, Small for Gestational Age, Bronchopulmonary Dysplasia (BPD), Anemia
Interventions
Liberal Cell Transfusion, Restricted red cell transfusion
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 48 Hours
Enrollment
1,824 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2025
U.S. locations
20
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 16 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 15, 2026, 4:48 PM EDT