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ClinicalTrials.gov public records Last synced Oct 13, 2026, 11:18 PM EDT

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Showing 193–216 of 850 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Infant, Premature Clear all
Completed Not applicable Interventional

Family Nurture Intervention (FNI) in Neonatal Intensive Care Unit (NICU)

NCT01439269
View directory record Official record
Conditions
Premature Birth
Interventions
Family Nurture Intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
26 Weeks to 34 Weeks
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Not applicable Interventional Results available

Cold Milk for Dysphagia in Preterm Infants

NCT04421482
View directory record Official record
Conditions
Dysphagia of Newborn
Interventions
Standard room temperature (RTS) feeding of milk/formula, Cold temperature (CS, at 4-9°C) of milk/formula
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Weeks and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 13, 2026, 11:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Epidemiology of Surfactant Protein-B Deficiency

NCT00014859
View directory record Official record
Conditions
Lung Diseases, Respiratory Distress Syndrome, Newborn, Pulmonary Surfactant, Lung Diseases, Interstitial
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 1 Year
Enrollment
5,176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 13, 2026, 11:18 PM EDT
Terminated Not applicable Interventional Results available

Proparacaine and Mydriatic Eye Drops

NCT01266824
View directory record Official record
Conditions
Pain, Retinopathy of Prematurity
Interventions
Proparacaine Hydrochloride Ophthalmic Solution
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2013 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Not applicable Interventional Results available

Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis

NCT01029353
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
Interventions
Laparotomy, Drainage
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 8 Weeks
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
22
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Oct 13, 2026, 11:18 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

NCT04995341
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Investigational ultracompact OCT and OCTA system, retinal photographs
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 13, 2026, 11:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Time Outside Target Oxygen Saturation Range in Preterm Infants and Long Term Outcomes and Preterm Infants

NCT00845624
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
1 Day to 12 Months
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2012 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Not applicable Interventional Results available

Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants

NCT03694613
View directory record Official record
Conditions
Preterm Infant, Early-Onset Neonatal Sepsis, Umbilical Cord
Interventions
Placental/Umbilical Cord Blood sample
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Up to 1 Day
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Phase 1Phase 2 Interventional

Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial

NCT01242462
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
Conventional Pressure Controlled SIMV, Mid-frequency Ventilation
Procedure · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Hour to 7 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 2, 2014 · Synced Oct 13, 2026, 11:18 PM EDT
Terminated No phase listed Observational

Biomarkers, Neurodevelopment and Preterm Infants

NCT02557191
View directory record Official record
Conditions
Preterm, Neurodevelopmental Disorder, Epigenetic Changes
Interventions
Observational study
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
1 Day to 2 Days
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 13, 2026, 11:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Generalized Movements for Early Prediction of Cerebral Palsy

NCT00749008
View directory record Official record
Conditions
Cerebral Palsy, Prematurity
Interventions
Not listed
Lead sponsor
Charles R. Neal,
Other
Eligibility
Up to 2 Months
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Feb 25, 2014 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Phase 4 Interventional Results available

Preterm Infant Inhaled Albuterol Dosing

NCT02447250
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Very Low Birth Weight
Interventions
Varied albuterol dose response
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
14 Days and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 13, 2026, 11:18 PM EDT
Active, not recruiting No phase listed Observational

Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next)

NCT04515524
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Non-Interventional
Other
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
11 Months to 5 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
9
States / cities
La Jolla, California • Loma Linda, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Not applicable Interventional

Effect of Protein Intake on Preterm Infant Body Composition

NCT02353013
View directory record Official record
Conditions
Premature; Infant, Light-for-dates
Interventions
Protein supplementation, Standard fortification
Dietary Supplement
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Minute to 1 Year
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 22, 2017 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Supporting Mothers of Preterm Infants

NCT03013660
View directory record Official record
Conditions
PreTerm Birth
Interventions
Limited Financial Support
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Lowell, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Phase 2Phase 3 Interventional

Probiotics-Supplemented Feeding in Extremely Low Birth Weight Infants

NCT01164124
View directory record Official record
Conditions
Low Birth Weight
Interventions
Probiotic supplementation (Lactobacillus rhamnosus GG and Bifidobacterium infantis), Placebo
Dietary Supplement · Other
Lead sponsor
Vermont Oxford Network
Network
Eligibility
1 Day to 14 Days
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
3
States / cities
Detroit, Michigan • St Louis, Missouri • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Phase 4 Interventional Results available

Physiologic Approach to Sodium Supplementation in Premature Infants

NCT03889197
View directory record Official record
Conditions
Postnatal Growth Disorder
Interventions
Sodium supplementation guided by urine sodium concentration algorithm
Drug
Lead sponsor
Indiana University
Other
Eligibility
7 Days to 16 Days
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 13, 2026, 11:18 PM EDT
Recruiting No phase listed Observational

Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

NCT06475976
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Chest computed tomography (CT) with angiography, Bronchoscopy with bronchoalveolar lavage, Echocardiography, 24 hour esophageal pH ("potential of hydrogen") - multichannel intraluminal impedance (MII) monitoring (reflux testing)
Diagnostic Test
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Month to 1 Year
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Not applicable Interventional Results available

Feeding and Wellness Among Late Preterm Infants

NCT00470717
View directory record Official record
Conditions
Late Preterm Infant
Interventions
Weekly telephone call
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 1, 2021 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Not applicable Interventional Results available

Effects of Reading to Preterm Infants on Baby and Parents' Well Being

NCT02518997
View directory record Official record
Conditions
Parental Infant Bonding, Cardio-respiratory Stability in Preterm NICU Infants
Interventions
Parental Reading Aloud
Other
Lead sponsor
Georgetown University
Other
Eligibility
7 Days to 40 Weeks
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Phase 4 Interventional

Premedication for Less Invasive Surfactant Administration Study (PRELISA)

NCT05065424
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn
Interventions
IV Atropine and Fentanyl Premedication Arm, IV Normal Saline Placebo Arm
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
0 Hours to 72 Hours
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 13, 2026, 11:18 PM EDT
Completed No phase listed Observational

Evaluating Decisional Regret Among Mothers

NCT04074525
View directory record Official record
Conditions
Extreme Prematurity, Birth, Preterm, Pregnancy Preterm
Interventions
Not listed
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older · Female only
Enrollment
211 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 13, 2026, 11:18 PM EDT
Completed Not applicable Interventional

Iron Status and Myelination in Premature Infants

NCT00684697
View directory record Official record
Conditions
Neurodevelopmental Outcome
Interventions
iron
Dietary Supplement
Lead sponsor
University of Rochester
Other
Eligibility
Up to 32 Weeks
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Oct 13, 2026, 11:18 PM EDT
Recruiting Not applicable Interventional

Impact of Hospital to Home: Optimizing Preterm Infant Environment for Surgical Neonates and Their Parents (H-HOPE)

NCT07372898
View directory record Official record
Conditions
Oral Feeding Outcomes, Neurodevelopment Outcome
Interventions
H-HOPE
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
1 Week to 8 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 13, 2026, 11:18 PM EDT