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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Infant, Premature Development Clear all
Completed Not applicable Interventional

Family Nurture Intervention (FNI) in Neonatal Intensive Care Unit (NICU)

NCT01439269
View directory record Official record
Conditions
Premature Birth
Interventions
Family Nurture Intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
26 Weeks to 34 Weeks
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Sep 25, 2026, 5:30 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Language Intervention Study of Preterm Infants

NCT03688386
View directory record Official record
Conditions
Language Development, Language Delay, Mother-Infant Interaction, Maternal Behavior
Interventions
Reading intervention, Infant bonding, LENA recording, LENA linguistic feedback, LENA summary
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
23 Weeks to 31 Weeks
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 25, 2026, 5:30 PM EDT
Not yet recruiting Not applicable Interventional

Eye Tracking and Autism in Former Preterm Infants

NCT07764822
View directory record Official record
Conditions
Autism, Prematurity
Interventions
Eye-tracking device
Device
Lead sponsor
Indiana University
Other
Eligibility
14 Months to 48 Months
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 25, 2026, 5:30 PM EDT
Terminated Not applicable Interventional

The Impact of Implementing NIDCAP on Preterm Infants in the NICU

NCT00179933
View directory record Official record
Conditions
Infant, Premature
Interventions
Newborn Individualized Assessment Program
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Not applicable Interventional Results available

Movement-based Infant Intervention

NCT03082313
View directory record Official record
Conditions
Infant Development, Infant,Premature, Infant, Very Low Birth Weight, Infant, Small for Gestational Age, Infant Conditions
Interventions
Movement Intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
3 Months to 9 Months
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Not applicable Interventional

Severe Intrauterine Growth Retardation: Developmental Newborn Intensive Care Unit (NICU) Care

NCT00914108
View directory record Official record
Conditions
Intrauterine Growth Retardation, Prematurity
Interventions
Newborn Individualized Developmental Care
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 36 Weeks
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2002
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 25, 2026, 5:30 PM EDT
Recruiting Not applicable Interventional

The Impact of Music Medicine on Preterm Brain Development and Behavior

NCT06536296
View directory record Official record
Conditions
Infant Development, Language Development, Prematurity, Stress
Interventions
Music, Music and parent voice, Standard Care
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
24 Weeks to 30 Weeks
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
2
States / cities
New Haven, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 25, 2026, 5:30 PM EDT
Not yet recruiting Not applicable Interventional

NICU-to-Home Dyadic Support for Very Preterm Infants and Families

NCT07820462
View directory record Official record
Conditions
Preterm Birth, Very Preterm Infant, Infant Development, Neonatal Intensive Care Unit
Interventions
Homebased SPEEDI, Telehealth SPEEDI
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
0 Years to 6 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy

NCT03230032
View directory record Official record
Conditions
Infant Development, Infant,Premature, Hydrocephalus, Neonatal Encephalopathy, Infarction, PVL, Thrombosis, Intraventricular Hemorrhage
Interventions
pacifier-activated device
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
32 Weeks to 12 Months
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Not applicable Interventional

Family Nurture Intervention in the NICU

NCT02710474
View directory record Official record
Conditions
Premature Birth, Obstetric Labor, Premature
Interventions
Family Nurture Intervention, Standard Care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
26 Weeks to 34 Weeks
Enrollment
461 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
New York, New York • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Sep 25, 2026, 5:30 PM EDT
Completed No phase listed Observational

Neurophysiologic Maturation Index for Late Preterm Infants

NCT02156817
View directory record Official record
Conditions
Neurophysiologic Maturation
Interventions
Amplitude integrated electroencephalogram, Cardiorespiratory signal acquisition
Other
Lead sponsor
Brown University
Other
Eligibility
1 Day to 4 Days
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Detroit, Michigan • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 25, 2026, 5:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Impact of Implementing NIDCAP on the Developmental Sensitivity of Nurses Caring for Preterm Infants

NCT00179985
View directory record Official record
Conditions
Infant, Premature Development
Interventions
Not listed
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 28, 2011 · Synced Sep 25, 2026, 5:30 PM EDT
Completed No phase listed Observational

Oral Entrainment on Suck Development of Preterm Infants Born 23 to 34 Weeks Gestational Age (GA)

NCT01069744
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
KC BioMediX, Inc
Industry
Eligibility
23 Weeks to 34 Weeks
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2010 · Synced Sep 25, 2026, 5:30 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants

NCT06063122
View directory record Official record
Conditions
Premature Birth
Interventions
smallTalk NICU Active
Device
Lead sponsor
Thrive Neuromedical, LLC
Industry
Eligibility
32 Weeks to 35 Weeks
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia • Chagrin Falls, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Sep 25, 2026, 5:30 PM EDT
Recruiting No phase listed Observational

Optimizing Nutrition and Milk (Opti-NuM) Project

NCT06870981
View directory record Official record
Conditions
Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant, Nutritional Requirements, Human Milk Fortification, Human Milk Microbiome, Human Milk Feeding, Human Milk Nutrition, Growth &Amp; Development
Interventions
Opti-NuM is an observational secondary use of data/samples study, the investigators will analyze information and specimens from the MaxiMoM platform RCTs. No interventions form part of this study.
Other
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
1 Hour to 21 Days
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
2
States / cities
Palo Alto, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Phase 1 Interventional

A Clinical Safety Study of AT-100 (rhSP-D) in Preterm Neonates at High Risk for Bronchopulmonary Dysplasia (BPD)

NCT04662151
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
AT-100, Air-sham
Biological · Procedure
Lead sponsor
Airway Therapeutics, Inc.
Industry
Eligibility
0 Minutes to 96 Hours
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
9
States / cities
Tucson, Arizona • Little Rock, Arkansas • Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 25, 2026, 5:30 PM EDT
Completed No phase listed Observational

Neurophysiological Maturation Correlate With Clinical Milestones

NCT03722901
View directory record Official record
Conditions
Neurophysiologic Maturation
Interventions
Not listed
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
Up to 4 Days
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 28, 2018 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Not applicable Interventional

Family Nurture Intervention in the NICU at The Valley Hospital

NCT03267043
View directory record Official record
Conditions
Premature Birth, Obstetric Labor, Premature
Interventions
Family Nurture Intervention (FNI), Standard Care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
26 Weeks to 34 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Ridgewood, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Sep 25, 2026, 5:30 PM EDT
Withdrawn Not applicable Interventional

Assisted Exercise in Prematurity; Effects and Mechanisms

NCT00580099
View directory record Official record
Conditions
Growth, Development
Interventions
assisted exercise, cuddle
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
30 Weeks to 35 Weeks
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2021 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Not applicable Interventional

Patterned Experience for Preterm Infants

NCT01577615
View directory record Official record
Conditions
Complication of Prematurity
Interventions
Patterned Experience
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 32 Weeks
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2015 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Not applicable Interventional

Music and Feeding in NICU

NCT02919358
View directory record Official record
Conditions
Feeding, NICU, Preterm Infants, Mozart, Weight Gain
Interventions
Music, No music.
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
28 Weeks to 31 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Sep 25, 2026, 5:30 PM EDT
Recruiting No phase listed Observational

Imaging Retinal Vasculature in Infant Eyes

NCT05558059
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Handheld Optical Coherence Tomography with OCT Angiography
Device
Lead sponsor
Duke University
Other
Eligibility
Up to 2 Months
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 25, 2026, 5:30 PM EDT
Completed No phase listed Observational

39946-I Laser and Bevacizumab Treatment for Retinopathy of Prematurity

NCT01993043
View directory record Official record
Conditions
ROP Threshold
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
30 Weeks to 40 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
2
States / cities
Houston, Texas • Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 25, 2026, 5:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Medicine to Reduce Developmental Delays

NCT04652063
View directory record Official record
Conditions
Extreme Prematurity, Neurodevelopmental Abnormality
Interventions
Osteopathic Manipulative Medicine
Other
Lead sponsor
University of Rochester
Other
Eligibility
1 Day to 14 Weeks
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 25, 2026, 5:30 PM EDT