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ClinicalTrials.gov public records Last synced Oct 22, 2026, 12:41 AM EDT

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Showing 385–408 of 851 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Infant,Premature Clear all
Completed Not applicable Interventional Results available

Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function

NCT04295564
View directory record Official record
Conditions
Neonatal, Premature Birth, Respiratory Distress Syndrome
Interventions
Additional 2 weeks of CPAP
Other
Lead sponsor
Cynthia McEvoy
Other
Eligibility
1 Day to 12 Weeks
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 22, 2026, 12:41 AM EDT
Terminated Phase 3 Interventional

Management of Hyponatremia in Preterm Infants on Diuretics

NCT00156572
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Hyponatremia on Diuretics
Interventions
Sodium supplementation, Fluid restriction
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
4 Weeks to 6 Months
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2007 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 3 Interventional

Caffeine for Apnea of Prematurity (CAP)

NCT00182312
View directory record Official record
Conditions
Apnea of Prematurity
Interventions
Caffeine citrate injection
Drug
Lead sponsor
McMaster University
Other
Eligibility
Up to 10 Days
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2018 · Synced Oct 22, 2026, 12:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

NCT04995341
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
Investigational ultracompact OCT and OCTA system, retinal photographs
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 22, 2026, 12:41 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP

NCT01939067
View directory record Official record
Conditions
Respiratory Distress, Lung Injury
Interventions
Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Hours to 72 Hours
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 15, 2015 · Synced Oct 22, 2026, 12:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Point-of-Care System for Determination of Bilirubin Capacity in Neonates

NCT02612207
View directory record Official record
Conditions
Jaundice, Neonatal, Hyperbilirubinemia, Bilirubin-Induced Neurological Dysfunction (BIND)
Interventions
Bilirubin Binding Capacity by Hematofluorometry Validation
Device
Lead sponsor
Stanford University
Other
Eligibility
6 Hours to 14 Days
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Stanford, California • Lakewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preemie Prep For Parents (P3): Home Antenatal Prematurity Education

NCT04093492
View directory record Official record
Conditions
Premature Birth, Decision Making, Prenatal Care, Resuscitation, Infant, Premature
Interventions
Preemie Prep for Parents (P3) Outpatient Mobile Intervention, ACOG links
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Not listed
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Antenatal Micronutrient Supplementation and Infant Survival

NCT00860470
View directory record Official record
Conditions
Infant Mortality, Preterm Birth, Low Birth Weight, Neonatal Mortality, Perinatal Mortality
Interventions
Iron (27 mg) - folic acid (600 ug), Multiple micronutrient
Dietary Supplement
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
12 Years to 45 Years · Female only
Enrollment
44,567 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 3 Interventional Results available

Study of Ataluren (PTC124™) in Cystic Fibrosis

NCT00803205
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Ataluren, Placebo
Drug
Lead sponsor
PTC Therapeutics
Industry
Eligibility
6 Years and older
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
21
States / cities
Birmingham, Alabama • Long Beach, California • Palo Alto, California + 16 more
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Phase 1b/2a Randomized, Double-Blind, Placebo-controlled, Dose-escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Preterm Infants

NCT02290340
View directory record Official record
Conditions
Respiratory Syncytial Virus
Interventions
Placebo, MEDI8897 10 mg, MEDI8897 25 mg, MEDI8897 50 mg
Drug
Lead sponsor
MedImmune LLC
Industry
Eligibility
Up to 12 Months
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
7
States / cities
Anaheim, California • Ontario, California • Syracuse, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Not applicable Interventional Results available

Effects of Reading to Preterm Infants on Baby and Parents' Well Being

NCT02518997
View directory record Official record
Conditions
Parental Infant Bonding, Cardio-respiratory Stability in Preterm NICU Infants
Interventions
Parental Reading Aloud
Other
Lead sponsor
Georgetown University
Other
Eligibility
7 Days to 40 Weeks
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Not applicable Interventional

Enhanced Nutrition for Preterm Infants

NCT03238768
View directory record Official record
Conditions
Preterm Birth
Interventions
Enhanced Intravenous Nutrition, Standard Intravenous Nutrition
Other
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 30 Weeks
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Oct 22, 2026, 12:41 AM EDT
Completed No phase listed Observational

Clinical Performance of the Embrace Isothermal Mattress

NCT01425086
View directory record Official record
Conditions
Hypothermia
Interventions
Embrace, PCM, warming blanket
Device
Lead sponsor
Stanford University
Other
Eligibility
1 Day to 120 Days
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 1 Interventional Results available

Metronidazole Pharmacokinetics (PK) in Premature Infants

NCT01222585
View directory record Official record
Conditions
Serious Systemic Infections, Necrotizing Enterocolitis
Interventions
Metronidazole
Drug
Lead sponsor
Michael Cohen-Wolkowiez
Other
Eligibility
Up to 90 Days
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
3
States / cities
Orange, California • Wichita, Kansas • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Oct 22, 2026, 12:41 AM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants

NCT04614714
View directory record Official record
Conditions
Preterm Birth, Inadequate Milk Production
Interventions
Nicotinamide Riboside (NR), Placebo
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 2 Interventional

PTC124 for Cystic Fibrosis

NCT00234663
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
PTC124
Drug
Lead sponsor
PTC Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
5
States / cities
Birmingham, Alabama • Palo Alto, California • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2009 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Not applicable Interventional

Re-feeding Gastric Residuals in Preterm Infants

NCT01420263
View directory record Official record
Conditions
Premature; Infant, Light-for-dates
Interventions
Re-feeding residuals, Fresh Feeding Breastmilk or Formula only
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 7 Days
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 11, 2013 · Synced Oct 22, 2026, 12:41 AM EDT
Recruiting Early Phase 1 Interventional

Metformin for Premature Infants With Bronchopulmonary Dysplasia

NCT07120971
View directory record Official record
Conditions
Bronchopulmonary Dysplasia (BPD)
Interventions
Metformin (open-label)
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
7 Days to 6 Months
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 22, 2026, 12:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Music's Effects on Premature Babies.

NCT00224211
View directory record Official record
Conditions
Stress, Sleep
Interventions
Music
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
1 Week to 3 Months
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 13, 2008 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Not applicable Interventional

Hydrolized Protein Formula for Premature Infants

NCT01156493
View directory record Official record
Conditions
Prematurity
Interventions
Protein Hydrolyzed Premature Formula
Other
Lead sponsor
University of Miami
Other
Eligibility
3 Days to 6 Months
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 1 Interventional

Seattle-PAP Bubble Nasal CPAP and Work of Breathing

NCT02210026
View directory record Official record
Conditions
Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia, Newborn Primary Sleep Apnea
Interventions
Seattle-PAP
Device
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
6 Hours to 72 Hours
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 1 Interventional

Early Blood Pressure Management in Extremely Premature Infants

NCT00874393
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Hypotension, Blood Pressure
Interventions
Dopamine, Hydrocortisone, Infusion Placebo, Syringe Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 24 Hours
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
17
States / cities
Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 13 more
Source: ClinicalTrials.gov public record
Updated May 25, 2017 · Synced Oct 22, 2026, 12:41 AM EDT
Completed Phase 2 Interventional

Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus

NCT00187447
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
indomethacin (two different dosing regimens)
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 48 Hours
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
3
States / cities
Davis, California • Chicago, Illinois • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 4, 2008 · Synced Oct 22, 2026, 12:41 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Clinical and Genetic Analysis of ROP

NCT04420156
View directory record Official record
Conditions
Retinopathy of Prematurity
Interventions
No intervention administered.
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Up to 1 Year
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2030
U.S. locations
5
States / cities
Palo Alto, California • Chicago, Illinois • Royal Oak, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Oct 22, 2026, 12:41 AM EDT