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Showing 217–240 of 3,541 matching trials from the live ClinicalTrials.gov search.
Completed Phase 1 Interventional Results available

Inhaled Tobramycin in BPD

NCT04560179
Conditions
Bronchopulmonary Dysplasia
Interventions
Tobramycin solution for inhalation 78mg dose, Tobramycin solution for inhalation 150mg dose, Tobramycin solution for inhalation 216mg dose, Tobramycin solution for inhalation 300mg dose
Drug
Lead sponsor
Erik Allen Jensen
Other
Eligibility
4 Weeks and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Cystic Fibrosis
Interventions
hydroxychloroquine
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
16 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Cystic Fibrosis
Interventions
lumacaftor, ivacaftor
Drug
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Eligibility
18 Years to 55 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Daytona Beach, Florida
Conditions
Intracranial Hemorrhages, Prematurity
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
Up to 14 Days
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers

Multi-site Trial Using SMS to Improve Infant Weight

NCT02903186
Conditions
Obesity
Interventions
SMS
Behavioral
Lead sponsor
University of Puerto Rico
Other
Eligibility
Up to 2 Months
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Honolulu, Hawaii
Completed Not applicable Interventional Results available

Behavioral & Nutritional Treatment to Help CF Preschoolers Grow

NCT00241969
Conditions
Cystic Fibrosis, Pancreatic Cystic Fibrosis
Interventions
Behavioral and Nutrition Treatment, Education and Attention Control
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
2 Years to 6 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
5
States / cities
Tucson, Arizona • Ann Arbor, Michigan • Cincinnati, Ohio + 2 more
Conditions
Cystic Fibrosis-related Diabetes, Cystic Fibrosis
Interventions
Metformin Hydrochloride
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Intraventricular Hemorrhage
Interventions
Standard 30-60 Seconds Cord Clamping, VentFirst 120 Seconds Cord Clamping
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
Not listed
Enrollment
570 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
10
States / cities
Birmingham, Alabama • Sacramento, California • Denver, Colorado + 7 more
Conditions
Pneumococcal Disease
Interventions
PG4, 20-valent pneumococcal conjugate vaccine (20vPnC)
Biological
Lead sponsor
Pfizer
Industry
Eligibility
42 Days to 98 Days
Enrollment
2,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
23
States / cities
Estero, Florida • Fort Lauderdale, Florida • Fort Myers, Florida + 16 more
Completed Not applicable Interventional Accepts healthy volunteers

SMS Maama Project COVID-19

NCT04739462
Conditions
Pregnancy Complications, Birth Injuries
Interventions
mHealth Platform
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older · Female only
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Hypothermia
Interventions
Embrace, PCM, warming blanket
Device
Lead sponsor
Stanford University
Other
Eligibility
1 Day to 120 Days
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Palo Alto, California
Terminated No phase listed Observational

Controlled Ventilation CT in CF Infants

NCT01200888
Conditions
Cystic Fibrosis
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
2 Months to 5 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Stanford, California
Completed No phase listed Observational Accepts healthy volunteers

Metabolome and Microbiomic in Fecal Samples

NCT00938028
Conditions
Infant
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Months to 20 Months
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Bedside Ultrasound Assistance on the Proportion of Successful Infant Spinal Taps

NCT02133066
Conditions
Traumatic Lumbar Puncture
Interventions
Bedside Ultrasound-Assisted Site Marking, Mindray M7 Ultrasound, Routine lumbar puncture
Procedure · Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 6 Months
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Cystic Fibrosis (CF), Non Cystic Fibrosis Bronchiectasis, Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Airway clearance therapy through acoustic oscillations
Device
Lead sponsor
Cognita Labs LLC
Industry
Eligibility
11 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Santa Ana, California
Conditions
Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Asthma
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
2 Months to 24 Months
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Anemia of Prematurity
Interventions
feed during blood transfusion
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
25 Weeks to 38 Weeks
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Cerebral Palsy
Interventions
Custom EMG triggered Soterix taVNS stimulation with CIMT therapy in lab, Custom EMG triggered Soterix taVNS stimulation with CIMT therapy in home
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Months to 18 Months
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Premature Infants
Interventions
RHO
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
Up to 37 Weeks
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
8
States / cities
Farmington, Connecticut • Lexington, Kentucky • Boston, Massachusetts + 5 more
Conditions
Infant Respiratory Distress Syndrome, Respiratory Insufficiency, Apnea of Prematurity
Interventions
Nasal high frequency ventilation
Other
Lead sponsor
Tarah T Colaizy
Other
Eligibility
7 Days to 3 Months
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Cystic Fibrosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
9 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
2
States / cities
Bethesda, Maryland • Milwaukee, Wisconsin
Conditions
Abdominal Pain, Abdominal Cramps, Flatulence
Interventions
BC-130 (Gas Defense), Placebo
Dietary Supplement
Lead sponsor
Miami Research Associates
Network
Eligibility
18 Years to 75 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Communities Helping the Hearing of Infants by Reaching Parents

NCT03875339
Conditions
Congenital Hearing Loss
Interventions
Navigator Guidance
Behavioral
Lead sponsor
Matthew Bush, MD
Other
Eligibility
Up to 99 Years
Enrollment
2,699 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Lexington, Kentucky • Louisville, Kentucky
Conditions
Microbiome
Interventions
Cleanser, Cleanser and Lotion
Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
3 Months to 6 Months
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Skillman, New Jersey