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Showing 1249–1272 of 3,545 matching trials from the live ClinicalTrials.gov search.
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients

NCT02496780
Conditions
Cystic Fibrosis
Interventions
novolog insulin, levemir insulin, placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
10 Years to 25 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Minneapolis, Minnesota • Saint Paul, Minnesota
Conditions
Cystic Fibrosis (CF)
Interventions
Loestrin (norethindrone acetate and ethinyl estradiol)
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Dallas, Texas
Conditions
Sickle Cell Anemia
Interventions
Hydroxyurea, Placebo
Drug · Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
6 Months to 12 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Mother Infant Nutrition Study

NCT04132310
Conditions
Pregnancy Related, Infant Development
Interventions
N/A This is an observational study.
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Austin, Texas
Conditions
Cystic Fibrosis, Pseudohypoaldosteronism, Nontuberculous Mycobacterial Infection, Chronic Granulomatous Disease, Primary Ciliary Dyskinesia
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
2 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Infant, Very Low Birth Weight
Interventions
Prolact-Plus Human Milk Fortifier
Procedure
Lead sponsor
Prolacta Bioscience
Industry
Eligibility
1 Day to 30 Days
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
4
States / cities
Gainesville, Florida • Hollywood, Florida • Miami, Florida + 1 more
Terminated Not applicable Interventional Accepts healthy volunteers

Term Infants Fed a Partially Hydrolyzed Whey Protein-Based Formula

NCT04934397
Conditions
Gastro-Intestinal Tolerance
Interventions
Study Infant Formula
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
7 Days to 65 Days
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
14
States / cities
Dothan, Alabama • Spring Hill, Florida • Idaho Falls, Idaho + 9 more
Conditions
Cystic Fibrosis
Interventions
7% Hypertonic Saline (HS), 0.9% Isotonic Saline (IS)
Drug
Lead sponsor
CF Therapeutics Development Network Coordinating Center
Network
Eligibility
4 Months to 59 Months
Enrollment
321 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
28
States / cities
Birmingham, Alabama • Phoenix, Arizona • Palo Alto, California + 24 more
Conditions
Pulmonary Artery Stenosis, Aortic Coarctation
Interventions
Minima Stent System
Device
Lead sponsor
Renata Medical
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
15
States / cities
Los Angeles, California • Aurora, Colorado • Miami, Florida + 12 more
Conditions
Body Composition, Beneficial
Interventions
Exercise/Social Behavioral
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
29 Weeks to 34 Weeks
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Orange, California
Conditions
Cardiovascular Diseases, Heart Diseases, Atherosclerosis, HIV Infections, Cardiomyopathy, Hypertrophic
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
Up to 2 Years
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
5
States / cities
Miami, Florida • Chicago, Illinois • Boston, Massachusetts + 2 more
Conditions
Achondroplasia
Interventions
BMN 111, Placebo
Drug
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
Up to 59 Months
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
9
States / cities
Oakland, California • Torrance, California • Wilmington, Delaware + 6 more
Completed No phase listed Observational Accepts healthy volunteers

Prediction of Jaundice in Term Infants

NCT01203410
Conditions
Infant, Newborn, Jaundice
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 8 Hours
Enrollment
535 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1991 – 1992
U.S. locations
13
States / cities
Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 10 more
Conditions
Congenital Cytomegalovirus Infection
Interventions
Letermovir
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
0 Days to 90 Days
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Birmingham, Alabama • Atlanta, Georgia • Milwaukee, Wisconsin
Conditions
Cystic Fibrosis
Interventions
Not listed
Lead sponsor
Foundation for the National Institutes of Health
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Los Angeles, California • Minneapolis, Minnesota • Salt Lake City, Utah
Conditions
Obesity and Overweight, Breastfeeding, Exclusive
Interventions
Chia seeds
Dietary Supplement
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 45 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Oklahoma City, Oklahoma
Conditions
Gastrointestinal Complication, Intestinal Obstruction, Gastroschisis, Hirschsprung Disease, Omphalocele, Midgut Volvulus
Interventions
Standard of Care, Exclusive Human Milk
Dietary Supplement
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
0 Days to 55 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Not listed No phase listed Observational Accepts healthy volunteers

Continuous Glucose Monitoring in Infants

NCT04458649
Conditions
Neonatal Hypoglycemia
Interventions
Dexcom continuous glucose monitor
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
1 Hour to 2 Hours
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
La Jolla, California
Conditions
Sepsis
Interventions
Daptomycin
Drug
Lead sponsor
Duke University
Other
Eligibility
48 Hours to 120 Days
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Mother-Baby Study - Observational

NCT06039878
Conditions
Obesity, Childhood, Obesity
Interventions
Bonding-Evoked Oxytocin, Distress Relieving Effects of Sucrose, Hedonic Response to Sucrose, Typical versus Challenging Feeding-Social, Caloric Compensation-Social, Ability to Delay Gratification for Food in Infants-Social Task (ATDG-FIT-Social)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
0 Days and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Iron-deficiency
Interventions
Iron Sulfate
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
7 Days to 4 Weeks
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Urea Cycle Disorder, Inborn Errors of Metabolism
Interventions
UCD Anamix Infant
Other
Lead sponsor
Nutricia Research
Industry
Eligibility
Up to 30 Days
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Active, not recruiting Phase 3 Interventional

RZ358 Treatment for Congenital Hyperinsulinism

NCT06208215
Conditions
Congenital Hyperinsulinism
Interventions
RZ358 (5 mg/kg) + SOC (Standard-of-Care) or Placebo + SOC, RZ358 (10 mg/kg) or Placebo + SOC, RZ358 (5-10 mg/kg) + SOC
Drug
Lead sponsor
Rezolute
Other
Eligibility
3 Months to 45 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Fort Worth, Texas
Conditions
Prone Positioning, Bronchopulmonary Dysplasia
Interventions
Prone positioning for a total of 6 hours daily
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
7 Days to 14 Weeks
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
The Bronx, New York