- Conditions
- Prosthetic-joint Infection, Dysbiosis
- Interventions
- Probiotic, Standard of care
- Drug · Other
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 152 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • New York, New York
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Showing 1–24
of 251
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Surgical Site Infection
- Interventions
- Prevena wound management system, Standard wound dressings
- Device · Other
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 298 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Staphylococcus Aureus Infection, Surgical Site Infection, Orthopedic Procedures, Spine
- Interventions
- Medium enriched for newly synthesized antibodies in spine infection
- Diagnostic Test
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Jaw Fractures, Infection
- Interventions
- Antibiotic treatment (Unasyn or Cleocin), Antibiotic treatment (Augmentin or Cleocin), Control Group
- Drug · Other
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 2
- States / cities
- Houston, Texas
- Conditions
- Surgical Wound Infection, Spinal Deformity, Spinal Degeneration
- Interventions
- Antibiotic Protocol
- Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 539 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
- Interventions
- Avance Solo Negative Pressure Wound Therapy
- Device
- Lead sponsor
- Molnlycke Health Care AB
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 104 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 8
- States / cities
- Washington D.C., District of Columbia • Indianapolis, Indiana • Baltimore, Maryland + 5 more
- Conditions
- Infections
- Interventions
- Normal saline pressurized irrigation, sub-q gentamicin
- Procedure · Drug
- Lead sponsor
- Dallas VA Medical Center
- Federal
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Cesarean Section Complications, Cesarean Wound; Dehiscence, Cesarean Wound Disruption
- Interventions
- PICO Negative Pressure Wound Therapy, Standard Dressing
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 50 Years · Female only
- Enrollment
- 153 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- New Hyde Park, New York
- Conditions
- Surgical Site Infection, Cesarean Section; Infection
- Interventions
- Abdominal Closure Bundle
- Procedure
- Lead sponsor
- Abington Memorial Hospital
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 850 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Abington, Pennsylvania
- Conditions
- Infection, Surgical Site
- Interventions
- Intraosseous Vancomycin Injection, Intravenous Vancomycin
- Drug
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 19 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- 30% Oxygen Concentration During Colorectal Surgery, 80% Oxygen Concentration During Colorectal Surgery
- Interventions
- 30% oxygen, 80% oxygen
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 5,749 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Surgical Site Infection
- Interventions
- DFA-02, Placebo
- Drug
- Lead sponsor
- Dr. Reddy's Laboratories Limited
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 5
- States / cities
- Florence, Alabama • Tampa, Florida • Columbus, Ohio + 2 more
- Conditions
- Surgery, Anaesthesia, Ventilator-Induced Lung Injury, Lung Injury, Pneumonia, Pneumothorax, Respiratory Distress Syndrome, Adult, Respiratory Insufficiency
- Interventions
- Not listed
- Lead sponsor
- European Society of Anaesthesiology
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10,690 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 3
- States / cities
- Aurora, Colorado • Boston, Massachusetts • Rochester, Minnesota
- Conditions
- Surgical Site Infection
- Interventions
- Implementation of the AO Trauma SSI Prevention Bundle
- Behavioral
- Lead sponsor
- AO Clinical Investigation and Publishing Documentation
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 222 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 8
- States / cities
- Los Angeles, California • Lexington, Kentucky • Worcester, Massachusetts + 5 more
- Conditions
- Infections, Surgery
- Interventions
- Silverlon, Standard of Care Dressing
- Other
- Lead sponsor
- Jorge Marcet
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Surgical Wound Infection
- Interventions
- Next Science, Standard of Care
- Device · Other
- Lead sponsor
- Next Science TM
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 2
- States / cities
- Birmingham, Alabama • Columbus, Georgia
- Conditions
- Surgery, Pneumonia, Surgical Site Infection
- Interventions
- Continuous Sternal Block, Opioid based analgesia
- Device · Drug
- Lead sponsor
- Halyard Health
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 647 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • Newark, Delaware • Lexington, Kentucky + 5 more
- Conditions
- Arm Fracture, Surgical Site Infection
- Interventions
- Chlorhexidine, Betadine
- Other
- Lead sponsor
- Geisinger Clinic
- Other
- Eligibility
- Up to 10 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Danville, Pennsylvania
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Interventions
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate, Light Only
- Device
- Lead sponsor
- Ondine Biomedical Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Bothell, Washington
- Conditions
- Surgical Site Infection
- Interventions
- Ertapenem, Cefazolin and Metronidazole.
- Drug
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Post Operative Surgical Site Infection
- Interventions
- Supplemental Perioperative Oxygen
- Procedure
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 1,171 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 2
- States / cities
- Phoenix, Arizona • Baltimore, Maryland
- Conditions
- Surgical Wound Infection, Preoperative Care, Methicillin-Resistant Staphylococcus Aureus
- Interventions
- Povidone-Iodine 10%, 0.9% NaCl Solution
- Drug
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 192 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Newark, New Jersey
- Conditions
- Abscess, Wound Infection, Surgical Site Infection, Cellulitis
- Interventions
- IV Dalbavancin, Vancomycin/Linezolid
- Drug
- Lead sponsor
- Durata Therapeutics Inc., an affiliate of Allergan plc
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 739 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 30
- States / cities
- Montgomery, Alabama • Anaheim, California • Buena Park, California + 26 more
- Conditions
- Wound Closure, Brain Tumor Adult, Spine, Neurovascular, Hemorrhagic Stroke, Intracerebral, Traumatic Brain Injury
- Interventions
- STRATAFIX PDS and Monocryl suture
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Lansing, Michigan