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Conditions: Peripheral Vascular Disease, Abdominal Aortic Aneurysm
Interventions: continuous intravenous insulin infusion; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Pancreatic Ductal, Tumor Virus Infections
Interventions: CC-486, Carboplatin, ABI-007; Drug
Lead sponsor: Celgene; Industry
Eligibility: 18 Years and older
Enrollment: 169 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 7
States / cities: Scottsdale, Arizona • San Francisco, California • Indianapolis, Indiana + 4 more

Conditions: Surgical Site Infection, Colon Surgery, Abdominal Surgery, Post-Op Infection
Interventions: D-PLEX, Standard of Care (SoC); Drug · Other
Lead sponsor: PolyPid Ltd.; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 975 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 5
States / cities: Augusta, Georgia • New Orleans, Louisiana • St Louis, Missouri + 2 more

Conditions: Pneumonia, Necrotizing Soft Tissue Infection, Intraabdominal Infections, Infection Joint
Interventions: Blue Light; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 65 Years
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Appendicitis
Interventions: Not listed
Lead sponsor: Peter Minneci; Other
Eligibility: 7 Years to 17 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Respiratory Tract Infections, Urinary Tract Infections, Intra-Abdominal Infections, Skin and Soft Tissue Infection, Suspected Meningitis/Encephalitis or Any Other Infection, Sepsis
Interventions: TriVerity; Diagnostic Test
Lead sponsor: Inflammatix; Industry
Eligibility: 18 Years and older
Enrollment: 1,441 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 25
States / cities: Mobile, Alabama • Los Angeles, California • Sacramento, California + 22 more

Conditions: Acute Appendicitis
Interventions: Ultrasound for Appendicitis; Procedure
Lead sponsor: WellSpan Health; Other
Eligibility: Not listed
Enrollment: 262 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: York, Pennsylvania

Conditions: Complicated Intra-Abdominal Infection
Interventions: CAZ-AVI, Metronidazole, Meropenem; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 493 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 4
States / cities: Chula Vista, California • San Diego, California • St Louis, Missouri + 1 more

Conditions: Post Operative Pain, Appendicitis
Interventions: Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic, Post-Closure Saline; Drug · Other
Lead sponsor: Valley Anesthesiology Consultants; Other
Eligibility: 9 Years to 17 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Abdomen Hernia
Interventions: Prevena, Prineo, Traditional; Device · Drug
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Abscess, Intra-Abdominal, Abdominal Abscess, Abdomen, Acute, Abdominal Pain, Appendicitis, Rupture, Infection, Intestinal Perforation, Peritonitis, Ileus
Interventions: Doripenem, Meropenem placebo, Meropenem, Doripenem placebo, Amoxicillin/clavulanate potassium; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 3 Months to 18 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 4
States / cities: San Diego, California • Washington D.C., District of Columbia • Cleveland, Ohio + 1 more

Conditions: Acute Kidney Injury, Septic Shock, Resuscitations
Interventions: Abdominal Perfusion Pressure (APP), Mean Arterial Pressure (MAP); Device
Lead sponsor: Potrero Medical; Industry
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: Little Rock, Arkansas • Atlanta, Georgia

Conditions: Complicated Appendicitis, Acute Appendicitis
Interventions: Ceftriaxone, Intra-peritoneal Fluid Aspiration; Drug · Procedure
Lead sponsor: Johns Hopkins All Children's Hospital; Other
Eligibility: 3 Years to 18 Years
Enrollment: 190 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Appendicitis
Interventions: Cost Information Included; Other
Lead sponsor: University of Utah; Other
Eligibility: Up to 17 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Acute Uncomplicated Appendicitis
Interventions: 1 gm IV ertapenem at enrollment, 1 gm IV ertapenem at Day 2 and oral metronidazole and cefdinir to complete 10 days, Appendectomy; Drug · Procedure
Lead sponsor: Olive View-UCLA Education & Research Institute; Other
Eligibility: 5 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Sylmar, California

Conditions: Gastritis, Peptic Ulcer, Peptic Ulcer Perforation, Stomach Ulcer
Interventions: Urea Breath Test (UBT) for H. pylori infection; Other
Lead sponsor: George Washington University; Other
Eligibility: 18 Years and older
Enrollment: 212 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 2
States / cities: Washington D.C., District of Columbia

Conditions: Appendicitis
Interventions: Not listed
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: 5 Years to 18 Years
Enrollment: 800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Saint Paul, Minnesota

Conditions: Surgical Wound Infection, Wound; Abdomen, Abdominal Wall, Surgery
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Peritonitis
Interventions: duration of antibiotics; Other
Lead sponsor: University of Virginia; Other
Eligibility: 16 Years and older
Enrollment: 518 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 22
States / cities: Phoenix, Arizona • Sacramento, California • San Diego, California + 17 more

Conditions: Perforated Appendicitis
Interventions: Motion sickness wristband, Chewing Gum; Device · Dietary Supplement
Lead sponsor: Wake Forest University; Other
Eligibility: 6 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: HIV-Associated Lipodystrophy Syndrome, Insulin Resistance, HIV Infections, Metabolic Syndrome X, Body Weight Changes
Interventions: Rosiglitazone, Recombinant human growth hormone + rosiglitazone; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 4
States / cities: New York, New York

Conditions: Appendicitis, Cholelithiasis, Gallstones
Interventions: Transvaginal Appendectomy, Transvaginal Cholecystectomy; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2019
U.S. locations: 1
States / cities: San Diego, California

Conditions: Appendicitis
Interventions: antibiotic duration; Other
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Louisville, Kentucky

Conditions: Helicobacter Pylori Infection, Gastric Ulcer, Nausea, Abdominal Pain, Weight Loss, Stomach Ulcer, Loss of Appetite, Bloating
Interventions: Newly Diagnosed; Other
Lead sponsor: DiaSorin Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 277 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 11
States / cities: Mesa, Arizona • Mission Hills, California • Oxnard, California + 8 more

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Glycemic Control to Prevent Cardiac Morbidity in Vascular Surgery

A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors

D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)

The Role of Circadian Clock Proteins in Innate and Adaptive Immunity

Non-operative Management of Early Appendicitis in Children

TriVerity in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis

Point of Care Ultrasound for Evaluation of Suspected Appendicitis in the Emergency Department

Compare Ceftazidime-Avibactam + Metronidazole Versus Meropenem for Hospitalized Adults With Complicated Intra-Abdominal Infections

Evaluation of Local Anesthetic at Incision Site

The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR

A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections

Targeting Abdominal Perfusion Pressure in Septic Shock

Antibiotic Instillation in Appendicitis

Laparoscopic Versus Open Appendectomy? Let the Patient Decide

Pilot Trial of Antibiotics Versus Surgery for Treating Acute Appendicitis

H. Pylori Testing for Patients With Non-specific Upper Abdominal Pain in the Emergency Department

Pediatric Appendicitis Risk Calculator (pARC) in Children With Appendix Ultrasounds

Surgical Site Infection Rate After Intra-Abdominal Surgery Using Negative Pressure Wound Therapy at Initial Closure

SIS Multicenter Study of Duration of Antibiotics for Intraabdominal Infection

The Effect of Gum Chewing on Postoperative Ileus

Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance

Minimally Invasive Surgery: Using Natural Orfices

Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)

Helicobacter Pylori Sample Collection Protocol Pre Therapy Subjects