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ClinicalTrials.gov public records Last synced Nov 7, 2026, 3:06 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 1,279 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Infection Prophylaxis Clear all

Conditions: HIV Infections
Interventions: Behavioral intervention, Risk-reduction counseling; Behavioral
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years and older · Male only
Enrollment: 4,350 participants
Healthy volunteers: Accepts healthy volunteers
U.S. locations: 6
States / cities: San Francisco, California • Denver, Colorado • Chicago, Illinois + 3 more

Conditions: HIV Infections
Interventions: CHECKIT!; Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years and older
Enrollment: 493 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: HIV Infections
Interventions: ChiCAS; Behavioral
Lead sponsor: Centers for Disease Control and Prevention; Federal
Eligibility: 18 Years and older · Male only
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: HIV
Interventions: computer-based HIV, STD & Hepatitis Education, educator-delivered HIV, STD and Hepatitis education; Procedure
Lead sponsor: National Development and Research Institutes, Inc.; Other
Eligibility: 13 Years to 18 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2004
U.S. locations: 2
States / cities: Brooklyn, New York • New York, New York

Conditions: Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
Interventions: Project Legacy; Behavioral
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 14 Years to 19 Years
Enrollment: 571 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 12
States / cities: Boyle Heights, California • Long Beach, California • Los Angeles, California + 3 more

Conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
Interventions: anti-thymocyte globulin, rituximab, sirolimus, tacrolimus, laboratory biomarker analysis, allogeneic hematopoietic stem cell transplantation, management of therapy complications, peripheral blood stem cell transplantation; Biological · Drug · Other + 1 more
Lead sponsor: Barbara Ann Karmanos Cancer Institute; Other
Eligibility: 18 Years to 120 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Surgical Site Infection, Sternal Infection, Cardiac Surgery
Interventions: D-PLEX, Standard of Care; Drug · Other
Lead sponsor: PolyPid Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: Rochester, Minnesota • Huston, Texas

Conditions: Anorectal Surgeries
Interventions: Epiflo; Device
Lead sponsor: Neogenix, LLC dba Ogenix; Industry
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Cytomegalovirus (CMV) Infections
Interventions: V160, Placebo; Biological · Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 16 Years to 35 Years · Female only
Enrollment: 2,200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 54
States / cities: Birmingham, Alabama • Chandler, Arizona • Rialto, California + 41 more

Conditions: Kidney Stones
Interventions: ciprofloxacin, cotrimoxazole-trimethoprim, macrodantin; Drug
Lead sponsor: University of British Columbia; Other
Eligibility: 19 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2023
U.S. locations: 11
States / cities: Scottsdale, Arizona • San Diego, California • Baltimore, Maryland + 8 more

Conditions: Fungal Infection
Interventions: Micafungin; Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 29 Days to 10 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: HIV Infection, Monoclonal Antibody, Human, HIV Antibodies, VRC01 Monoclonal Antibody, Neutralizing Antibody
Interventions: VRC-HIVMAB060-00-AB; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Hiv
Interventions: Preventing AIDS Through Live Movement and Sound (PALMS); Behavioral
Lead sponsor: Centers for Disease Control and Prevention; Federal
Eligibility: 12 Years to 18 Years · Male only
Enrollment: 264 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Clostridium Difficile Infection
Interventions: Oral Vancomycin, Placebo; Drug
Lead sponsor: Rochester General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Rochester, New York

Conditions: HIV Infections, Pre-exposure Prophylaxis, Substance Use Disorders
Interventions: Motivational Interviewing (MI), Contingency Management (CM); Behavioral
Lead sponsor: Florida International University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Opioid Use, Opioid Use Disorder, Risk Reduction, Hiv, Hepatitis C
Interventions: Suboxone, Truvada, Mavyret; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 2
States / cities: Durham, North Carolina • Greensboro, North Carolina

Conditions: Sore-throat, Dysphonia, Dysphagia, Intubation Complication, Anesthesia Intubation Complication, Anesthesia Morbidity, Anesthesia Complication, Anesthesia; Adverse Effect, Anesthesia; Reaction, Throat Disorder, Throat; Wound, Throat Injury
Interventions: EndoClip; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Influenza, Common Cold, Cough, Headache, Fever
Interventions: Pomegranate, Placebo; Dietary Supplement
Lead sponsor: Texas Heart Institute; Other
Eligibility: 21 Years to 49 Years
Enrollment: 461 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: San Diego, California

Conditions: Influenza, Healthy
Interventions: Monovalent Influenza Vaccine, Placebo; Biological · Other
Lead sponsor: MedImmune LLC; Industry
Eligibility: 18 Years to 49 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 2
States / cities: Stockbridge, Georgia • Portland, Oregon

Conditions: Group B Streptococcal Infection
Interventions: Vaginal and rectovaginal swab cultures; Biological
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older · Female only
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: HIV Infections
Interventions: Maximal Control, Instrumental and Empowering, Minimal Control, Instrumental, Empowering; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years to 35 Years
Enrollment: 722 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Herpes Simplex
Interventions: Acyclovir; Drug
Lead sponsor: Southern Illinois University; Other
Eligibility: 24 Months and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: HIV Prevention, HIV Infections
Interventions: tenofovir + emtricitabine, lopinavir/ritonavir; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 267 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Heart Transplant Infection Prevention
Interventions: PCV15; Biological
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: The Bronx, New York

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HIV Prevention Counseling for Men Who Have Sex With Men

Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement Study

HIV Prevention Among Latina Transgender Women Who Have Sex With Men: Evaluation of a Locally Developed Intervention

Computer-Assisted HIV Prevention for Young Drug Users

Project Legacy Impact Evaluation Study

Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation

D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery

Transdermal Continuous Oxygen Therapy for Infection Prophylaxis in High- Risk Patients Undergoing Colon Surgery

V160 2-Dose and 3-Dose Regimens in Healthy Cytomegalovirus (CMV) Seronegative Females (V160-002)

Struvite Stones Antibiotic Study

Alternate Day Micafungin: A PK Study in Pediatric Patients

Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB060-00-AB (VRC01), Administered Intravenously or Subcutaneously to Healthy Adults

Evaluation of the Preventing AIDS Through Live Movement and Sound (PALMS) Intervention for Minority Adolescents

Oral Vancomycin for Preventing Clostridium Difficile Recurrence

PrEP Readiness Interventions for Supporting Motivation

Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP

No Post Intubation Laryngeal Symptoms

Pomegranate Products for Prevention of Common Cold

Study to Evaluate the Safety of 1 New 6:2 Influenza Virus Reassortant in Adults for the 2017-2018 Season

Intrapartum Effect of Vancomycin on Rectovaginal GBS Colonization

Selective Exposure in HIV Prevention

Antiviral Prophylaxis in a Burn Population

Interventions for HIV Negative Men and Women Who Have High-risk Suspected Exposure to HIV

MISP 60528 Pneumococcal Vaccination