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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Inguinal Hernia Clear all
Terminated Not applicable Interventional

SEMPERFLO* Pain Management System in Inguinal Hernia Repair

NCT00423241
View directory record Official record
Conditions
Inguinal Hernia, Pain
Interventions
SEMPERFLO Pain Management System, ON-Q PainBuster Post-Op Pain Relief System
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
6
States / cities
Boca Raton, Florida • Jacksonville, Florida • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2010 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Transabdominal Plane (TAP) Blocks for Inguinal Hernia Repairs

NCT05672680
View directory record Official record
Conditions
Inguinal Hernia
Interventions
0.25% Bupivacaine, Placebo, TAP block
Drug · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Jul 23, 2026, 2:43 AM EDT
Not listed No phase listed Observational

Early Surgeon Experience With Robotic-Assisted Inguinal Hernia Repair

NCT04353687
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
Robotic-assisted inguinal hernia repair
Device
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Newport News, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Phase 4 Interventional Results available

Awake Caudal Catheter vs General Anesthesia

NCT05919732
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Bupivacaine, Dexmedetomidine, Caffeine, Tylenol, Propofol, rocuronium, caffeine, Tylenol, bupivacaine
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
23 Weeks to 60 Weeks
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Jul 23, 2026, 2:43 AM EDT
Terminated Not applicable Interventional

Freedom Inguinal Hernia Repair System Study

NCT01984996
View directory record Official record
Conditions
Primary Inguinal Hernia
Interventions
Freedom ProFlor Inguinal Hernia Implant
Device
Lead sponsor
Insightra Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
4
States / cities
Los Angeles, California • Lebanon, Indiana • Baton Rouge, Louisiana + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Jul 23, 2026, 2:43 AM EDT
Terminated Phase 3 Interventional Results available

Ibuprofen to Decrease Opioid Use and Post-operative Pain Following Unilateral Inguinal Herniorrhaphy

NCT02929589
View directory record Official record
Conditions
Pain, Hernia
Interventions
Ibuprofen, Opioid Medication, Placebo, Ibuprofen + Opioid medication
Drug
Lead sponsor
Mike O'Callaghan Military Hospital
Federal
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Jul 23, 2026, 2:43 AM EDT
Active, not recruiting No phase listed Observational

Natural History of Infants With Patent Processus Vaginalis

NCT03042858
View directory record Official record
Conditions
Patent Processus Vaginalis, Inguinal Hernia
Interventions
Infants with PPV, Infants without PPV
Other
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 4 Months
Enrollment
801 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transversus Abdominus Plane Catheters for Open Inguinal Hernia Repair

NCT02741492
View directory record Official record
Conditions
Post-Operative Pain
Interventions
Transversus Abdominis Plane Block, Sham Block
Procedure
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Not applicable Interventional

Timing of Inguinal Hernia Repair in Premature Infants

NCT01678638
View directory record Official record
Conditions
Inguinal Hernia, Premature Birth of Newborn
Interventions
IH repair before NICU discharge, IH repair at 55-60 weeks post-menstrual age
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 37 Weeks
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
40
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 33 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Phase 3 Interventional Results available

Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)

NCT03237481
View directory record Official record
Conditions
Postoperative Pain
Interventions
HTX-011, Bupivacaine HCl, Saline placebo, Luer-lock applicator, Vial access device
Drug · Device
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
22
States / cities
Florence, Alabama • Sheffield, Alabama • Phoenix, Arizona + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 23, 2026, 2:43 AM EDT
Active, not recruiting Phase 4 Interventional

No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

NCT05929937
View directory record Official record
Conditions
Postoperative Pain, Inguinal Hernia
Interventions
Opioids, No opioids
Drug · Other
Lead sponsor
Clayton Petro
Other
Eligibility
18 Years and older
Enrollment
904 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Fountain Valley, California • Royal Oak, Michigan • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Jul 23, 2026, 2:43 AM EDT
Not listed Phase 3 Interventional

Does Preoperative Caldolor Decrease the Requirement for Postoperative Narcotics

NCT01297829
View directory record Official record
Conditions
Postoperative Pain
Interventions
Intravenous Ibuprofen, IV Placebo
Drug · Other
Lead sponsor
St. Barnabas Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Livingston, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 15, 2014 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Not applicable Interventional Results available

Inguinal Hernia Study Using Biodesign IHM

NCT00393887
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Biodesign IHM, Polypropylene mesh
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Phase 4 Interventional Results available

A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants

NCT00756600
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Regional Anesthesia, General Anesthesia
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 60 Weeks
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
10
States / cities
Aurora, Colorado • Chicago, Illinois • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2020 · Synced Jul 23, 2026, 2:43 AM EDT
Completed No phase listed Observational

Pain and Quality of Life After Inguinal Hernia Repair

NCT04074200
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Open Inguinal Hernia Repair, Laparoscopic Inguinal Hernia Repair, Robotic-Assisted Inguinal Hernia Repair
Procedure · Device
Lead sponsor
Intuitive Surgical
Industry
Eligibility
18 Years to 80 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years

NCT00716768
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Laparoscopic Inguinal Hernia Repair, Open Inguinal Hernia Repair
Procedure
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Up to 3 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Jul 23, 2026, 2:43 AM EDT
Recruiting Not applicable Interventional

De-Implementation of Low-value Testing in Patients Undergoing Low-Risk Surgery

NCT06934564
View directory record Official record
Conditions
Breast Lumpectomy, Laparoscopic Cholecystectomy, Inguinal Hernia Repair
Interventions
Active de-Implementation
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Not applicable Interventional

Watchful Waiting Versus Open Tension-free Repair of Inguinal Hernia in Asymptomatic or Minimally Symptomatic Men

NCT00263250
View directory record Official record
Conditions
Inguinal Hernia
Interventions
watchful waiting or tension-free hernia repair
Procedure
Lead sponsor
Creighton University
Other
Eligibility
18 Years and older · Male only
Enrollment
724 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2013 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Phase 3 Interventional

Does Tension-Free Herniorrhaphy or Laparoscopic Herniorrhaphy Achieve Equal or Better Recurrence Rates and Lower Costs While Achieving Equivalent Outcomes for Hernia Patients?

NCT00032448
View directory record Official record
Conditions
Hernia
Interventions
Standardized tension-free herniorrhaphy with prosthesis
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Male only
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
14
States / cities
Birmingham, Alabama • No. Little Rock, Arkansas • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2011 · Synced Jul 23, 2026, 2:43 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Tamsulosin to Prevent Postoperative Urinary Retention in Laparoscopic Inguinal Hernia Repair

NCT04434378
View directory record Official record
Conditions
Post Operative Urinary Retention
Interventions
Tamsulosin, Placebo
Drug
Lead sponsor
Jewish Hospital, Cincinnati, Ohio
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Jul 23, 2026, 2:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bassini Inguinal Hernia Repair: Obsolete Or Still A Viable Surgical Option?

NCT04888078
View directory record Official record
Conditions
Inguinal Hernia, Surgery--Complications, Surgical Complication
Interventions
Bassini hernia repair
Procedure
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 16, 2021 · Synced Jul 23, 2026, 2:43 AM EDT
Completed Phase 3 Interventional Results available

The POUR (Postoperative Urinary Retention) Study

NCT05276804
View directory record Official record
Conditions
Postoperative Urinary Retention
Interventions
Sugammadex
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Jul 23, 2026, 2:43 AM EDT
Not yet recruiting Not applicable Interventional

Image-Guided Herniorrhaphy Study

NCT07267494
View directory record Official record
Conditions
Hernia, Hernia Abdominal Wall, Ventral Hernia, Inguinal Hernia, Hiatal Hernia, Diastasis Recti
Interventions
Image-Guided Herniorrhaphy
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Jul 23, 2026, 2:43 AM EDT
Recruiting Not applicable Interventional

Watchful Waiting Versus Immediate Repair for Occult Contralateral Inguinal Hernias.

NCT07461558
View directory record Official record
Conditions
Inguinal Hernia Bilateral, Inguinal Hernia Unilateral
Interventions
surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Watchful waiting with supportive care
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 23, 2026, 2:43 AM EDT