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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:39 PM EDT

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Showing 25–48 of 91 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Inguinal Hernia Clear all
Terminated Not applicable Interventional

SEMPERFLO* Pain Management System in Inguinal Hernia Repair

NCT00423241
View directory record Official record
Conditions
Inguinal Hernia, Pain
Interventions
SEMPERFLO Pain Management System, ON-Q PainBuster Post-Op Pain Relief System
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
6
States / cities
Boca Raton, Florida • Jacksonville, Florida • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2010 · Synced Oct 20, 2026, 5:39 PM EDT
Active, not recruiting Phase 4 Interventional

No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

NCT05929937
View directory record Official record
Conditions
Postoperative Pain, Inguinal Hernia
Interventions
Opioids, No opioids
Drug · Other
Lead sponsor
Clayton Petro
Other
Eligibility
18 Years and older
Enrollment
904 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Fountain Valley, California • Royal Oak, Michigan • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Not applicable Interventional Results available

Laryngeal Mask Airway in Laparoscopic Hernia Repair

NCT06023394
View directory record Official record
Conditions
Inguinal Hernia, Inguinal Hernia, Indirect, Inguinal Hernia Bilateral, Inguinal Hernia Unilateral
Interventions
Laryngeal Mask Airway, Endotracheal Tube Device
Device
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
12 Months to 8 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Phase 3 Interventional Results available

Surgical Pain After Inguinal Hernia Repair (SPAIHR)

NCT00551135
View directory record Official record
Conditions
Pain, Postoperative, Hernia, Inguinal
Interventions
Pregabalin, placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
17 Years to 75 Years · Male only
Enrollment
425 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
24
States / cities
Birmingham, Alabama • Glendale, California • Laguna Hills, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 20, 2026, 5:39 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain

NCT05386693
View directory record Official record
Conditions
Hernia, Inguinal, Chronic Postoperative Pain
Interventions
Ilioinguinal nerve block
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mastery Learning Inguinal Hernia Repair

NCT01085500
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Mastery Learning TEP Curriculum, Current Practice
Behavioral · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 28, 2016 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Not applicable Interventional Results available

Telescopic Dissection vs. Balloon Dissection During Laparoscopic TEP Inguinal Hernia Repair

NCT03276871
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Telescopic Dissection, Balloon Dissection
Procedure · Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2020 · Synced Oct 20, 2026, 5:39 PM EDT
Active, not recruiting Early Phase 1 Interventional

Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

NCT05177991
View directory record Official record
Conditions
Inguinal Hernia, Ventral Hernia
Interventions
Liposomal Bupivacaine, Bupivacaine
Drug
Lead sponsor
Leslie Son
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 20, 2026, 5:39 PM EDT
Not listed No phase listed Observational

Use of Parietex Plug and Patch Hernia System in Open Inguinal Hernia Repair

NCT01590940
View directory record Official record
Conditions
Evaluate the Use of a New Mesh Type in Open Inguinal Hernia Repair
Interventions
Open inguinal hernia repair with mesh
Procedure
Lead sponsor
Owen Drive Surgical Clinic of Fayetteville
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Fayetteville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2012 · Synced Oct 20, 2026, 5:39 PM EDT
Not listed Phase 3 Interventional

Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair

NCT03262688
View directory record Official record
Conditions
Inguinal Hernia, Postoperative Pain
Interventions
Bupivacaine HCl collagen-matrix implant, Bupivacaine HCl infiltration
Drug
Lead sponsor
Innocoll
Industry
Eligibility
2 Years to 16 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
11
States / cities
Laguna Hills, California • Altamonte Springs, Florida • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2021 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Phase 4 Interventional

Extended Delivery of Bupivacaine Study in Herniorrhaphy

NCT04102267
View directory record Official record
Conditions
Analgesia
Interventions
Bupivacaine liposome injectable suspension, Bupivacaine HCl without epinephrine via continuous infusion
Drug
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transversus Abdominus Plane Catheters for Open Inguinal Hernia Repair

NCT02741492
View directory record Official record
Conditions
Post-Operative Pain
Interventions
Transversus Abdominis Plane Block, Sham Block
Procedure
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Not applicable Interventional Results available

Inguinal Hernia Study Using Biodesign IHM

NCT00393887
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Biodesign IHM, Polypropylene mesh
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 20, 2015 · Synced Oct 20, 2026, 5:39 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Rebound Hernia Repair Device Mesh Trial

NCT00968773
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Rebound HRD, Standard hernia mesh (VitaMesh)
Device
Lead sponsor
Minnesota Medical Development, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
2
States / cities
Lexington, Kentucky • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 15, 2016 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Phase 2 Interventional Results available

Efficacy, Safety and Pharmacokinetic Profile of a Collagen Bupivacaine Implant in Men After Open Mesh Herniorrhaphy

NCT00626886
View directory record Official record
Conditions
Postoperative Pain, Inguinal Hernia
Interventions
Bupivacaine Collagen Sponge, placebo collagen sponge
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older · Male only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 20, 2026, 5:39 PM EDT
Active, not recruiting Phase 4 Interventional

Methocarbamol in Ventral and Inguinal HR

NCT05388929
View directory record Official record
Conditions
Ventral Hernia, Inguinal Hernia
Interventions
Methocarbamol, Standard Opioid, Standard opioid plus methocarbamol
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 20, 2026, 5:39 PM EDT
Recruiting Phase 4 Interventional

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

NCT05722002
View directory record Official record
Conditions
Surgery, Pain, Postoperative
Interventions
NSAID, Opioid, Acetaminophen
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
6
States / cities
Ann Arbor, Michigan • Detroit, Michigan • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 20, 2026, 5:39 PM EDT
Recruiting No phase listed Observational

Robotic Minimally Invasive Inguinal Hernia Repair Post-Market Clinical Study With the DEXTER Robotic System

NCT07181876
View directory record Official record
Conditions
Inguinal Hernia Repair
Interventions
inguinal hernia repair
Device
Lead sponsor
Distalmotion SA
Industry
Eligibility
22 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Buffalo, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Not applicable Interventional

The Role of the Robotic Platform in Inguinal Hernia Repair Surgery

NCT02816658
View directory record Official record
Conditions
Hernia, Inguinal
Interventions
Laparoscopic Inguinal Hernia Repair, Robotic Inguinal Hernia Repair
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
6
States / cities
St Louis, Missouri • New York, New York • Wilmington, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 20, 2026, 5:39 PM EDT
Terminated Not applicable Interventional

Freedom Inguinal Hernia Repair System Study

NCT01984996
View directory record Official record
Conditions
Primary Inguinal Hernia
Interventions
Freedom ProFlor Inguinal Hernia Implant
Device
Lead sponsor
Insightra Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
4
States / cities
Los Angeles, California • Lebanon, Indiana • Baton Rouge, Louisiana + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2016 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Not applicable Interventional Results available

Postoperative Activity Restrictions in Children

NCT04145895
View directory record Official record
Conditions
Pediatric Post-operative Time to Return to Full Activity
Interventions
Postoperative activity restrictions
Other
Lead sponsor
Corewell Health East
Other
Eligibility
Not listed
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years

NCT00716768
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Laparoscopic Inguinal Hernia Repair, Open Inguinal Hernia Repair
Procedure
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Up to 3 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Phase 3 Interventional

Does Tension-Free Herniorrhaphy or Laparoscopic Herniorrhaphy Achieve Equal or Better Recurrence Rates and Lower Costs While Achieving Equivalent Outcomes for Hernia Patients?

NCT00032448
View directory record Official record
Conditions
Hernia
Interventions
Standardized tension-free herniorrhaphy with prosthesis
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Male only
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
14
States / cities
Birmingham, Alabama • No. Little Rock, Arkansas • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2011 · Synced Oct 20, 2026, 5:39 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Determine the Clinical Advantage of IV vs PO Acetaminophen

NCT03558555
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Acetaminophen IV Soln, Oral Acetaminophen, Placebo Pills, Saline
Drug
Lead sponsor
Yan Lai
Other
Eligibility
18 Years to 75 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Oct 20, 2026, 5:39 PM EDT