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ClinicalTrials.gov public records Last synced Oct 2, 2026, 8:00 AM EDT

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Showing 25–48 of 90 matching trials from the live ClinicalTrials.gov search.
Conditions
Hernia, Postoperative Pain
Interventions
5x5cm bupivacaine collagen sponges
Drug
Lead sponsor
Innocoll
Industry
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Bellaire, Texas
Conditions
Hernia, Inguinal, Chronic Postoperative Pain
Interventions
Ilioinguinal nerve block
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Results available

Preoperative Etanercept Before Inguinal Hernia Surgery

NCT00825344
Conditions
Inguinal Hernia, Postoperative Pain
Interventions
Etanercept, Saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Not yet recruiting Not applicable Interventional

Image-Guided Herniorrhaphy Study

NCT07267494
Conditions
Hernia, Hernia Abdominal Wall, Ventral Hernia, Inguinal Hernia, Hiatal Hernia, Diastasis Recti
Interventions
Image-Guided Herniorrhaphy
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Sacramento, California
Conditions
Inguinal Hernia
Interventions
TLC590, Naropin
Drug
Lead sponsor
Taiwan Liposome Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Draper, Utah
Active, not recruiting Phase 2 Interventional

Treatment of Occult Inguinal Hernias

NCT04815707
Conditions
Inguinal Hernia
Interventions
Occcult hernia repair
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Houston, Texas
Completed Not applicable Interventional Results available

Postoperative Activity Restrictions in Children

NCT04145895
Conditions
Pediatric Post-operative Time to Return to Full Activity
Interventions
Postoperative activity restrictions
Other
Lead sponsor
Corewell Health East
Other
Eligibility
Not listed
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Conditions
Pain, Analgesia, Hernia, Inguinal
Interventions
Gabapentin, placebo
Drug · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Completed Not applicable Interventional Results available

Inguinal Hernia Study Using Biodesign IHM

NCT00393887
Conditions
Inguinal Hernia
Interventions
Biodesign IHM, Polypropylene mesh
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Inguinal Hernia, Pain
Interventions
SEMPERFLO Pain Management System, ON-Q PainBuster Post-Op Pain Relief System
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
6
States / cities
Boca Raton, Florida • Jacksonville, Florida • St Louis, Missouri + 3 more
Conditions
Postoperative Pain, Inguinal Hernia
Interventions
Opioids, No opioids
Drug · Other
Lead sponsor
Clayton Petro
Other
Eligibility
18 Years and older
Enrollment
904 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Fountain Valley, California • Royal Oak, Michigan • Cleveland, Ohio + 3 more
Conditions
Inguinal Hernia
Interventions
Regional Anesthesia, General Anesthesia
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 60 Weeks
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
10
States / cities
Aurora, Colorado • Chicago, Illinois • Iowa City, Iowa + 7 more
Conditions
Hernia, Inguinal, Convalescence
Interventions
GENEactiv
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Scottsdale, Arizona
Completed Phase 2Phase 3 Interventional Results available

Transabdominal Plane (TAP) Blocks for Inguinal Hernia Repairs

NCT05672680
Conditions
Inguinal Hernia
Interventions
0.25% Bupivacaine, Placebo, TAP block
Drug · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Conditions
Postoperative Pain
Interventions
Bupivacaine HCl, SKY0402
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Male only
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
7
States / cities
Arcadia, California • Laguna Hills, California • Pasadena, California + 3 more
Conditions
Mucopolysaccharidosis (MPS)
Interventions
Not listed
Lead sponsor
Shire
Industry
Eligibility
Up to 7 Years · Male only
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
7
States / cities
Los Angeles, California • Jacksonville, Florida • Minneapolis, Minnesota + 4 more
Conditions
Inguinal Hernia
Interventions
Urinary Catheter
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
491 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Patent Processus Vaginalis, Inguinal Hernia
Interventions
Infants with PPV, Infants without PPV
Other
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 4 Months
Enrollment
801 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2036
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Hernia, Inguinal, Post Operative Pain
Interventions
local anaesthetic injection of CPL-01, Morphine (rescue medication), Acetaminophen (rescue medication), Oxycodone (rescue medication), local anaesthetic injection of placebo, local anaesthetic injection of ropivacaine HCl, Open inguinal hernia repair
Drug · Procedure
Lead sponsor
Cali Pharmaceuticals LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
518 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Postoperative Pain
Interventions
HTX-011, Bupivacaine HCl, Saline placebo, Luer-lock applicator, Vial access device
Drug · Device
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
22
States / cities
Florence, Alabama • Sheffield, Alabama • Phoenix, Arizona + 18 more
Completed No phase listed Observational Accepts healthy volunteers

Analgesia in Children Using Caudal Epidural Ropivacaine

NCT01494272
Conditions
Inguinal Hernia, Circumcision
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
2 Months to 2 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
2
States / cities
Loma Linda, California
Conditions
Opioid Use, Inguinal Hernia, Ventral Hernia
Interventions
Opioid Use Agreement
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Bellaire, Texas • Houston, Texas • Sugar Land, Texas
Completed Phase 2 Interventional Results available

Phase 2 Herniorrhaphy Study for Opioid Elimination

NCT03695367
Conditions
Postoperative Pain
Interventions
HTX-011, Luer lock applicator, Vial access device, Ibuprofen, Acetaminophen, Ketorolac
Drug · Device
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
5
States / cities
Anaheim, California • Pasadena, California • Draper, Utah + 2 more
Conditions
Inguinal Hernia
Interventions
PVB using nerve stimulation, PVB using anatomic landmarks
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Jacksonville, Florida