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ClinicalTrials.gov public records Last synced Oct 25, 2026, 4:42 PM EDT

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Showing 817–840 of 1,565 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Injuries, Craniocerebral Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Community-based Implementation of Online EmReg

NCT05933629
View directory record Official record
Conditions
Traumatic Brain Injury, Emotion Regulation
Interventions
Online EmReg, Consultation Sessions
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 25, 2026, 4:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Interactive Training in Sports Concussion Prevention and Management

NCT01978795
View directory record Official record
Conditions
Concussion
Interventions
Brain 101 website, Control
Other
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 8, 2013 · Synced Oct 25, 2026, 4:42 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Spectacles Lens in Concussed Kids

NCT03123822
View directory record Official record
Conditions
Concussion, Mild, Convergence Insufficiency, Accommodation; Insufficiency
Interventions
Glasses
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
9 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Oct 25, 2026, 4:42 PM EDT
Completed No phase listed Observational

Post-market Assessment of Biodesign Dural Repair Grafts

NCT04057157
View directory record Official record
Conditions
Cerebrospinal Fluid Leak
Interventions
Biodesign Dural or Duraplasty Repair Grafts
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 14, 2022 · Synced Oct 25, 2026, 4:42 PM EDT
Enrolling by invitation Phase 2 Interventional

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

NCT05826912
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Atorvastatin Calcium, Minocycline Hydrochloride, Candesartan Cilexetil, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
672 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
18
States / cities
San Francisco, California • Indianapolis, Indiana • Lexington, Kentucky + 14 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 25, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Concussion Education Programs

NCT04492696
View directory record Official record
Conditions
Concussion, Brain
Interventions
Education
Other
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 19 Years · Male only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 25, 2026, 4:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Morning Bright Light to Improve Sleep Quality in Veterans

NCT03578003
View directory record Official record
Conditions
Brain Injuries, Traumatic, Post-traumatic Stress Disorder
Interventions
Morning Bright Light Therapy
Other
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Portand, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 25, 2026, 4:42 PM EDT
Withdrawn Phase 2 Interventional

Promoting Upright Mobility in Infants With Cerebral Palsy Using a Robotic Unweighting System

NCT06593886
View directory record Official record
Conditions
Cerebral Palsy, Physical Therapy Modalities, Brain Injuries
Interventions
BabyG
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Months to 18 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 25, 2026, 4:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic Encephalopathy

NCT02079766
View directory record Official record
Conditions
Chronic Traumatic Encephalopathy
Interventions
florbetapir F 18, Flortaucipir F18
Drug
Lead sponsor
Avid Radiopharmaceuticals
Industry
Eligibility
Male only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Phoenix, Arizona • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 7, 2020 · Synced Oct 25, 2026, 4:42 PM EDT
Not listed Not applicable Interventional

Online Intervention for Traumatic Brain Injury Wellbeing

NCT05115656
View directory record Official record
Conditions
Traumatic Brain Injury, Attention Impaired, Emotional Regulation
Interventions
Online group 1, Online group 2
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 25, 2026, 4:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

REsting and Stimulus-based Paradigms to Detect Organized NetworkS and Predict Emergence of Consciousness

NCT03504709
View directory record Official record
Conditions
Consciousness Disorder, Coma, Brain Injuries, Traumatic
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 25, 2026, 4:42 PM EDT
Completed Not applicable Interventional

Effects of Aerobic Exercise on Cognition, Mood and Fatigue Following TBI

NCT00619463
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Exercise
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2013 · Synced Oct 25, 2026, 4:42 PM EDT
Not listed No phase listed Observational

Hormone Deficiency After Brain Injury During Combat

NCT01666964
View directory record Official record
Conditions
Traumatic Brain Injury, Hypopituitarism
Interventions
Blast Traumatic Brain Injury
Other
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 16, 2012 · Synced Oct 25, 2026, 4:42 PM EDT
Completed Not applicable Interventional

CONcussion Treatment After Combat Trauma (CONTACT)

NCT01387490
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Individualized Scheduled Telephone Support (ISTS), Usual Care (UC)
Behavioral · Other
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years and older
Enrollment
366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Durham, North Carolina • Fort Bragg, North Carolina • Fort Lewis, Washington + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2016 · Synced Oct 25, 2026, 4:42 PM EDT
Completed No phase listed Observational

Multimodal Approach to Testing the Acute Effects of Mild Traumatic Brain Injury (mTBI)

NCT02069613
View directory record Official record
Conditions
Concussion, Mild
Interventions
Not listed
Lead sponsor
Huntington Medical Research Institutes
Other
Eligibility
18 Years to 50 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Oct 25, 2026, 4:42 PM EDT
Withdrawn Not applicable Interventional

Remote Ischemic Conditioning in Traumatic Brain Injury

NCT03899532
View directory record Official record
Conditions
Traumatic Brain Injury, Brain Injuries, Brain Trauma, Brain Injuries, Traumatic
Interventions
Remote Ischemic Conditioning, No-Remote Ischemic Conditioning
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
17 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 25, 2026, 4:42 PM EDT
Completed Not applicable Interventional

Survivors of Sex Trafficking: Occupation-Based Interventions for Executive Functioning

NCT03611998
View directory record Official record
Conditions
Sex Trafficking, Mental Disorder
Interventions
Occupation-based programming
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
19 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 25, 2026, 4:42 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy

NCT03554265
View directory record Official record
Conditions
Traumatic Brain Injury, Fatigue, Cognitive Impairment, COVID-19
Interventions
Somatropin
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 70 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 25, 2026, 4:42 PM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athletes With Co-morbid Depression and Concussion

NCT07507214
View directory record Official record
Conditions
Concussion, Depression
Interventions
ONE-D TMS protocol and d-cycloserine (125 mg)
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Ocala, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 25, 2026, 4:42 PM EDT
Terminated Not applicable Interventional

Improving Functional Ability in Chronic TBI With Intensive Rehabilitation Robotic Gait Training

NCT03438409
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Robotic gait training
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 6, 2018 · Synced Oct 25, 2026, 4:42 PM EDT
Suspended Not applicable Interventional

Virtual Reality Treadmill Training in Individuals With Traumatic Brain Injury

NCT05721209
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
C-Mill with AR/VR Guidance, C-Mill without AR/VR Guidance, Zeno 3-Layer Walkway, Hunova
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 25, 2026, 4:42 PM EDT
Recruiting No phase listed Observational

Correlation Between Noninvasive Blood Vessel Functionality Parameters and Cerebral Hemodynamics in Neurocritical Care Patients

NCT06511804
View directory record Official record
Conditions
Brain Injuries, Intracranial Pressure Increase, Monitoring
Interventions
Intracranial Pressure Noninvasive Monitoring
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Oct 25, 2026, 4:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Flortaucipir F 18

NCT02278367
View directory record Official record
Conditions
Alzheimer's Disease, Traumatic Brain Injury, Depression
Interventions
Flortaucipir F18, Brain PET scan
Drug · Procedure
Lead sponsor
Avid Radiopharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
5
States / cities
Phoenix, Arizona • New Haven, Connecticut • Las Vegas, Nevada + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Oct 25, 2026, 4:42 PM EDT
Completed No phase listed Observational

Stryker's Surgeon iD Mandible Reconstruction Plates: A Retrospective Post Market Follow Up

NCT07221916
View directory record Official record
Conditions
Mandible Fracture, Mandibular Reconstruction
Interventions
Mandibular Reconstruction
Device
Lead sponsor
Stryker Craniomaxillofacial
Industry
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 25, 2026, 4:42 PM EDT