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ClinicalTrials.gov public records Last synced Nov 1, 2026, 5:19 AM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1321–1344 of 1,565 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Injuries, Craniocerebral Clear all
Completed No phase listed Observational Accepts healthy volunteers

Stroke and Cerebrovascular Diseases Registry

NCT03281590
View directory record Official record
Conditions
Stroke, Acute Stroke, Acute Brain Injury, Ischemic Stroke, Hemorrhagic Stroke, Transient Ischemic Attack, Subarachnoid Hemorrhage, Cerebral Ischemia, Cerebral Infarction, Cerebral Stroke, Venous Sinus Thrombosis, Cranial
Interventions
Not listed
Lead sponsor
University of New Mexico
Other
Eligibility
1 Year and older
Enrollment
4,594 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Nov 1, 2026, 5:19 AM EST
Recruiting No phase listed Observational

Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury

NCT06480838
View directory record Official record
Conditions
Traumatic Brain Injury With Loss of Consciousness, Brain Injury Traumatic Severe, Brain Injury Traumatic Moderate, TBI (Traumatic Brain Injury), TBI
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
3
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Nov 1, 2026, 5:19 AM EST
Completed Not applicable Interventional

A Pilot Randomized Controlled Trial: CoINTEGRATE

NCT05732285
View directory record Official record
Conditions
Neurocognitive Disorders, Cognitive Dysfunction, Traumatic Brain Injury, Multiple Sclerosis, Mild Cognitive Impairment
Interventions
CRT, CBT, Modifiable lifestyle factors, Usual care Psychoeducation
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Nov 1, 2026, 5:19 AM EST
Completed Not applicable Interventional Results available

Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI

NCT01921179
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Mild Traumatic Brain Injury, Concussion
Interventions
GOALS (Goal-Oriented Attentional Regulation), EDU (Brain Health Education)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Martinez, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Nov 1, 2026, 5:19 AM EST
Completed Phase 2 Interventional

Study of NNZ-2566 in Patients With Traumatic Brain Injury

NCT00805818
View directory record Official record
Conditions
Brain Injuries
Interventions
NNZ-2566, Placebo
Drug
Lead sponsor
Neuren Pharmaceuticals Limited
Industry
Eligibility
18 Years to 70 Years · Male only
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
20
States / cities
Mobile, Alabama • Tucson, Arizona • Colton, California + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Nov 1, 2026, 5:19 AM EST
Terminated Not applicable Interventional Results available

Advanced MRI Applications for Mild Traumatic Brain Injury - UCSF

NCT02141360
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
MRI Diagnostic
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
15 Years to 50 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Nov 1, 2026, 5:19 AM EST
Completed Phase 4 Interventional Results available

Simvastatin for mTBI

NCT01952288
View directory record Official record
Conditions
TBI-Traumatic Brain Injury
Interventions
simvastatin, Placebo Oral Tablet
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Nov 1, 2026, 5:19 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

ImPACT Online Clinical Study

NCT02701842
View directory record Official record
Conditions
Brain Concussion
Interventions
ImPACT Online/Paper Pencil Tests, ImPACT Online
Device
Lead sponsor
ImPACT Applications, Inc.
Industry
Eligibility
12 Years to 59 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Nov 1, 2026, 5:19 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits in Children

NCT02712996
View directory record Official record
Conditions
Traumatic Brain Injury, Attention Deficit Disorder
Interventions
Lisdexamfetamine, Placebo
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
6 Years to 16 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Nov 1, 2026, 5:19 AM EST
Recruiting Not applicable Interventional

Symptom-Targeted Approach to Rehabilitation for Concussion (STAR-C)

NCT06855186
View directory record Official record
Conditions
Mild Traumatic Brain Injury (mTBI)
Interventions
Symptom-Targeted Approach to Rehabilitation for Concussion
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Wahiawa, Hawaii • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Nov 1, 2026, 5:19 AM EST
Completed No phase listed Observational

Near-infrared Spectroscopy (NIRS) for Intracranial Hematoma Detection in Children

NCT02149082
View directory record Official record
Conditions
Intracranial Hematoma
Interventions
Infrascanner Model 2000
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 18 Years
Enrollment
465 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2018 · Synced Nov 1, 2026, 5:19 AM EST
Not listed Not applicable Interventional

Theta Burst Stimulation for Headaches After Traumatic Brain Injury

NCT04906603
View directory record Official record
Conditions
Post-Traumatic Headache, Transcranial Magnetic Stimulation, Brain Injuries, Traumatic, Quality of Life
Interventions
Theta Burst Stimulation
Device
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Nov 1, 2026, 5:19 AM EST
Completed Phase 2 Interventional

Cannabinoids and Traumatic Brain Injury: A Randomized, Placebo Controlled Trial

NCT05632627
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Cannabidiol, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Nov 1, 2026, 5:19 AM EST
Completed Not applicable Interventional Results available

Acute Neurobehavioral Program for Improving Functional Status After TBI

NCT01166386
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
FANCI
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2022 · Synced Nov 1, 2026, 5:19 AM EST
Completed Phase 2 Interventional

Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI)

NCT01220713
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post-Concussive Syndrome
Interventions
Hyperbaric Oxygen Therapy
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
19 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Portsmouth, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 27, 2013 · Synced Nov 1, 2026, 5:19 AM EST
Not yet recruiting Not applicable Interventional

A Pilot Study of Home-Based Rhythmic Auditory Stimulation to Evaluate Mobility, Balance, and Patient-Reported Outcomes After Traumatic Brain Injury

NCT07702513
View directory record Official record
Conditions
Traumatic Brain Injury, Traumatic Brain Injury | Patient, TBI, TBI-Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Interventions
Home-Based Rhythmic Auditory Stimulation
Device
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Nov 1, 2026, 5:19 AM EST
Recruiting No phase listed Observational

Augmented Renal Clearance in Neurocritical Care

NCT07410624
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Status Epilepticus, Bacterial Meningitis, Augmented Renal Clearance (ARC), Subarachnoid Hemorrhage, Aneurysmal, Ischemic Stroke, Intracerebral Hemorrhage
Interventions
Not listed
Lead sponsor
University of Alberta
Other
Eligibility
18 Years to 85 Years
Enrollment
512 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Lexington, Kentucky • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Nov 1, 2026, 5:19 AM EST
Not listed Not applicable Interventional

Do AxoGuard Implants Decrease Shoulder Disability After Neck Dissections

NCT03941327
View directory record Official record
Conditions
Spinal Accessory Nerve Injury, Cervical Lymphadenopathy
Interventions
AxoGuard Nerve Cuff
Device
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Nov 1, 2026, 5:19 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Integrated Eye Tracking and Neural Monitoring for TBI: Optimization

NCT03451058
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 55 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2022 · Synced Nov 1, 2026, 5:19 AM EST
Recruiting No phase listed Observational

Automated Robotic TCD in Traumatic Brain Injury

NCT05848297
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Transcranial Doppler ultrasonography (TCD)
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Timeline
2025 – 2027
U.S. locations
3
States / cities
Davis, California • Winston-Salem, North Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Nov 1, 2026, 5:19 AM EST
Recruiting No phase listed Observational Accepts healthy volunteers

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

NCT04439552
View directory record Official record
Conditions
Pain, Postoperative, Pain, Chronic, Pain, Acute, Surgical Injury, Surgical Wound, Cornea Injury, Cornea, Keratoconus
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Nov 1, 2026, 5:19 AM EST
Completed Phase 2 Interventional Results available

Sumatriptan as Treatment for Post-traumatic Headache

NCT01854385
View directory record Official record
Conditions
Post-traumatic Headache
Interventions
Sumatriptan 100 mg
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Nov 1, 2026, 5:19 AM EST
Not listed Not applicable Interventional

Assistive Soft Skills and Employment Training (ASSET) in TBI Injury

NCT05705817
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Assistive Soft Skills and Employment Training (ASSET)
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
15 Years to 25 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Nov 1, 2026, 5:19 AM EST
Not listed No phase listed Observational

Follow-up of MTBI Patients Discharged from the ED Using Standard Clinical Triage Including BrainScope One

NCT04279431
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Concussion, Brain, MTBI - Mild Traumatic Brain Injury, Closed Head Injury
Interventions
EEG Recording, Neurocognitive Tests, Clinician Evaluation, 22-item CSI
Device · Other
Lead sponsor
BrainScope Company, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
7
States / cities
Detroit, Michigan • Royal Oak, Michigan • Troy, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Nov 1, 2026, 5:19 AM EST