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ClinicalTrials.gov public records Last synced Nov 3, 2026, 2:23 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1537–1560 of 1,565 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Injuries, Craniocerebral Clear all
Completed No phase listed Observational Accepts healthy volunteers

Consistency of Automated Neuropsychological Assessment Metrics (ANAM) Performance in Those With Deployment Acquired Mild Traumatic Brain Injury (TBI)

NCT01334528
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post-Concussive Symptoms
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 45 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 15, 2016 · Synced Nov 3, 2026, 2:23 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Development of Quality of Life Tool for TBI

NCT00714428
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
485 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
4
States / cities
Palo Alto, California • Tampa, Florida • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 7, 2015 · Synced Nov 3, 2026, 2:23 PM EST
Completed Not applicable Interventional

Strength and Awareness in Action: an Intervention for Post-Acute TBI Headaches (SAA-TBI)

NCT03277859
View directory record Official record
Conditions
Traumatic Brain Injury, Post-concussive Headaches
Interventions
SAA-TBI
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 55 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Nov 3, 2026, 2:23 PM EST
Terminated Not applicable Interventional Results available

Effects of Combined Spinal Direct Current Stimulation on Upper Limb Recovery in Acquired Brain Injury

NCT03100370
View directory record Official record
Conditions
Acquired Brain Injury
Interventions
tsDCS-Anodal Stimulation, tsDCS-Cathodal Stimulation, tsDCS-Sham Stimulation, Robotic-assisted training of arm and hand functions
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Nov 3, 2026, 2:23 PM EST
Completed Not applicable Interventional

TBI Care: Collaborative Care for Pain After Traumatic Brain Injury (TBI)

NCT03523923
View directory record Official record
Conditions
Brain Injuries, Traumatic, Chronic Pain, Post-Traumatic Headache
Interventions
Collaborative Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Nov 3, 2026, 2:23 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Plasma Neurofilament Light and Its Relationship With Omega-3 Status and Soccer Heading in Women Soccer Players

NCT05457023
View directory record Official record
Conditions
Brain Trauma
Interventions
Plasma Neurofilament Light (NF-L), Omega-3 Index, HeadCount Questionnaire
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Nov 3, 2026, 2:23 PM EST
Terminated Not applicable Interventional Results available

Thalamic Low Intensity Focused Ultrasound in Brain Injury

NCT02522429
View directory record Official record
Conditions
Consciousness Disorders, Brain Injuries
Interventions
Low Intensity Focused Ultrasound Device
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Nov 3, 2026, 2:23 PM EST
Completed Early Phase 1 Interventional Results available

Assessment of Dystussia in Traumatic Brain Injury

NCT02240329
View directory record Official record
Conditions
TBI, Brain Injury
Interventions
Neuropsychological Testing and Measures of TBI severity, Respiratory measures, Capsaicin cough sensitivity testing
Behavioral · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 28, 2015 · Synced Nov 3, 2026, 2:23 PM EST
Completed Not applicable Interventional

Cognitive Therapy to Improve Word Finding

NCT00494520
View directory record Official record
Conditions
Anomia, Aphasia, Traumatic Brain Injury, Cerebrovascular Accident
Interventions
Errorful training condition, Errorless training condition
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2017 · Synced Nov 3, 2026, 2:23 PM EST
Terminated Not applicable Interventional

Effects of an Interdisciplinary Fitness and Social Engagement Intervention

NCT03160313
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
InFuSE, Patient Education/Group Discussion
Behavioral
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Nov 3, 2026, 2:23 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers

Study of the Safety of USB005 in Healthy Volunteers

NCT03615196
View directory record Official record
Conditions
Healthy Volunteers
Interventions
USB005 (aclerastide) Ophthalmic Solution, USB005 Ophthalmic Solution Placebo
Drug
Lead sponsor
US Biotest, Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cypress, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Nov 3, 2026, 2:23 PM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Indirect Intracranial Pressure Measurement in Patients With Suspected or Documented Concussion

NCT02699359
View directory record Official record
Conditions
Brain Concussion, Brain Injuries
Interventions
HS-1000 recording
Device
Lead sponsor
HeadSense Medical
Industry
Eligibility
12 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Nov 3, 2026, 2:23 PM EST
Terminated Phase 2 Interventional Results available

Pilot rTMS for AUD+mTBI

NCT03995173
View directory record Official record
Conditions
Alcohol Use Disorder, Mild Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
repetitive transcranial magnetic stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 30, 2026 · Synced Nov 3, 2026, 2:23 PM EST
Completed Not applicable Interventional

Cognitive Behavior Therapy for Insomnia (CBT-I) in Persons With Traumatic Brain Injury (TBI)

NCT02709980
View directory record Official record
Conditions
TBI, Insomnia
Interventions
Sleep Education, Cognitive Behavior Therapy for Insomnia
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Nov 3, 2026, 2:23 PM EST
Recruiting No phase listed Observational

The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

NCT04855396
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
16 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
10
States / cities
San Diego, California • West Palm Beach, Florida • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Nov 3, 2026, 2:23 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Mindfulness for Cognition in Early-stage Alzheimer's Disease

NCT06792877
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease, TBI (Traumatic Brain Injury), Aging, Healthy Elderly, Alzheimer&Amp;Amp;#39;s Dementia (AD)
Interventions
Mindfulness Intervention, Waitlist then mindfulness
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
50 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Nov 3, 2026, 2:23 PM EST
Enrolling by invitation No phase listed Observational

Multi-Institutional IMPACT Validation

NCT06850857
View directory record Official record
Conditions
Facial Injuries, Mandible Fracture, Le Fort, Zygomaticomaxillary Complex Fracture, Nasal Fracture, Orbital Fractures, Zygoma Fracture, Orbital Floor Fracture, Facial Laceration
Interventions
IMPACT-G Module, IMPACT-N Module, IMPACT-O Module, IMPACT-J Module, 15D Control Survey
Other
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Sacramento, California • San Francisco, California • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Nov 3, 2026, 2:23 PM EST
Withdrawn No phase listed Observational

Correlation of Scheimpflug Densitometry Measurements of Corneal Haze With Disability Glare

NCT02244892
View directory record Official record
Conditions
Vision Disability
Interventions
Not listed
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2022 · Synced Nov 3, 2026, 2:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Youth Soccer Header Study

NCT04919707
View directory record Official record
Conditions
Brain Injuries
Interventions
Header Session, MRI Session
Behavioral · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
12 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Nov 3, 2026, 2:23 PM EST
Completed Phase 2 Interventional Results available

A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment

NCT03276975
View directory record Official record
Conditions
Cerebrospinal Fluid Leaks
Interventions
TISSEEL
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Nov 3, 2026, 2:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Traumatic Brain Injury and the Gut Microbiome

NCT04949607
View directory record Official record
Conditions
Brain Injury, Chronic, Brain Injuries, Traumatic
Interventions
Inulin fructooligosaccharide
Dietary Supplement
Lead sponsor
Centre for Neuro Skills
Industry
Eligibility
18 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Nov 3, 2026, 2:23 PM EST
Withdrawn No phase listed Observational Accepts healthy volunteers

Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment, Young Adults and Adults

NCT03249675
View directory record Official record
Conditions
Concussion, Brain
Interventions
Not listed
Lead sponsor
ElMindA Ltd
Industry
Eligibility
12 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Brighton, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Nov 3, 2026, 2:23 PM EST
Not listed No phase listed Observational Accepts healthy volunteers

An Observational, Qualitative Study Assessing Eye Drop Administration

NCT05307081
View directory record Official record
Conditions
Ocular Injury
Interventions
Artificial Tears
Drug
Lead sponsor
Ocular Therapeutix, Inc.
Industry
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Sep 16, 2022 · Synced Nov 3, 2026, 2:23 PM EST
Completed Not applicable Interventional Results available

Metacognitive Training to Enhance Strategy Use in Blast-Related TBI

NCT00857207
View directory record Official record
Conditions
Brain Concussion, Blast Injuries
Interventions
Goal Management Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 30, 2021 · Synced Nov 3, 2026, 2:23 PM EST