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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional

Cannabinoids and Traumatic Brain Injury: A Randomized, Placebo Controlled Trial

NCT05632627
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Cannabidiol, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Not applicable Interventional Results available

Carbamazepine for the Treatment of Chronic Post-Traumatic Brain Injury Irritability and Aggression

NCT00621751
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Carbamazepine, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
16 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Sep 25, 2026, 4:48 AM EDT
Active, not recruiting Not applicable Interventional

Home Based Tele-exercise for People With Chronic Neurological Impairments

NCT04564495
View directory record Official record
Conditions
Neurologic Disorder, Stroke, Spinal Cord Injuries, Cerebral Palsy, Hemiplegia, Hemiparesis, Multiple Sclerosis, Parkinson Disease, Trauma, Brain, Transverse Myelitis, Friedreich Ataxia
Interventions
Seated exercise
Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Not applicable Interventional

Sleep After Adolescent Concussion

NCT03781076
View directory record Official record
Conditions
Brain Concussion
Interventions
Sleep Intervention
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Phase 4 Interventional

Myobloc Atrophy Study

NCT02052024
View directory record Official record
Conditions
Spasticity Secondary to Either a Disorder or Trauma, Spinal Cord Injury (SCI), Brain Injury, Tumor, Stroke
Interventions
Botox, MYOBLOC
Drug
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced Sep 25, 2026, 4:48 AM EDT
Recruiting No phase listed Observational

Screening Emotions in Adolescents at the Hospital for mTBI

NCT06370520
View directory record Official record
Conditions
Brain Injury Traumatic Mild, Brain Injuries, Brain Injuries, Acute, Head Injury With Intracranial Hemorrhage, Head Injury Trauma, Brain Injury Traumatic Focal With Loss of Consciousness, Skull Fractures, Diffuse Axonal Injury, Intracranial Hemorrhages, Head Injury
Interventions
Validated Questionnaires, Questionnaires, Clinician / Medical Record Variables
Behavioral · Other
Lead sponsor
University of California, Davis
Other
Eligibility
11 Years to 17 Years
Enrollment
2,592 participants
Timeline
2024 – 2028
U.S. locations
6
States / cities
Sacramento, California • Philadelphia, Pennsylvania • Providence, Rhode Island + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 25, 2026, 4:48 AM EDT
Active, not recruiting Not applicable Interventional

Early Feasibility Study of Cartilage Defect Repair

NCT06823089
View directory record Official record
Conditions
Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease, Osteochondral Lesion, Hip Dysplasia
Interventions
ReNew Hip Implant
Device
Lead sponsor
Cytex Therapeutics, Inc.
Other
Eligibility
14 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 25, 2026, 4:48 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Imaging [18F]PI-2620 and [18F]Florbetaben in Military Service Members With Blast Related Mild Traumatic Brain Injury

NCT05337774
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
[18F]PI-2620
Drug
Lead sponsor
Lantheus Biosciences Ltd.
Industry
Eligibility
25 Years to 54 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Phase 2 Interventional

Study of NNZ-2566 in Patients With Traumatic Brain Injury Under EFIC

NCT01366820
View directory record Official record
Conditions
Brain Injuries
Interventions
NNZ-2566, Placebo
Drug
Lead sponsor
Neuren Pharmaceuticals Limited
Industry
Eligibility
16 Years to 75 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
6
States / cities
Colton, California • Sacramento, California • Honolulu, Hawaii + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Long-term Effects of Blueberry Supplementation on Brain Health in Older Adults

NCT05764824
View directory record Official record
Conditions
Cognitive Decline, Nutrition, Healthy, Brain Injuries
Interventions
Blueberry powder, Controlled and matched powder
Dietary Supplement · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years to 99 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 25, 2026, 4:48 AM EDT
Recruiting Phase 3 Interventional

Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)

NCT06333990
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Quetiapine Fumarate, TAU
Drug
Lead sponsor
Foundation for Advancing Veterans' Health Research
Other
Eligibility
18 Years to 65 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Albuquerque, New Mexico • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Phase 2 Interventional

Amifostine to Treat Side Effects of Treatment in Patients Receiving Radiation Therapy and Cisplatin for Advanced Head and Neck Cancer

NCT00003580
View directory record Official record
Conditions
Drug/Agent Toxicity by Tissue/Organ, Head and Neck Cancer, Oral Complications, Radiation Toxicity
Interventions
amifostine trihydrate, cisplatin, radiation therapy
Drug · Radiation
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 25, 2013 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Phase 2 Interventional

Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest

NCT00797680
View directory record Official record
Conditions
Cardiac Arrest, Brain Injury
Interventions
72 hours hypothermia, 24 hours hypothermia
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
1 Week to 17 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2016 · Synced Sep 25, 2026, 4:48 AM EDT
Withdrawn Not applicable Interventional

Amantadine and Temporal Discrimination in Patients With Traumatic Brain Injury (TBI)

NCT00800514
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
amantadine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 25, 2026, 4:48 AM EDT
Active, not recruiting Not applicable Interventional

Brain Stimulation for Concussion

NCT05889117
View directory record Official record
Conditions
Transcranial Magnetic Stimulation, Magnetic Resonance Imaging, Neuropsychological Tests, Traumatic Brain Injury, Post-Concussion Syndrome
Interventions
Intermittent theta-burst treatment (iTBS) using MagPro Transcranial Magnetic Stimulator (manufacturer: Magventure)
Device
Lead sponsor
The Mind Research Network
Other
Eligibility
18 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 25, 2026, 4:48 AM EDT
Withdrawn No phase listed Observational

Characterization of Fatigue in Military Personnel With Traumatic Brain Injuries

NCT03998358
View directory record Official record
Conditions
Traumatic Brain Injury, Neurobehavioral Manifestation, Sleep Disorder, Fatigue
Interventions
Not listed
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
25 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Sep 25, 2026, 4:48 AM EDT
Not listed Not applicable Interventional

The Effects of MBSR on Patients With TBI and Chronic Insomnia

NCT03560843
View directory record Official record
Conditions
Chronic Insomnia, TBI (Traumatic Brain Injury)
Interventions
MBSR
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Sep 25, 2026, 4:48 AM EDT
Completed No phase listed Observational

Non-Interventional F-Two Isoprostane Trial (NIFTI)

NCT00505908
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 15, 2020 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blast Exposed Veterans With Auditory Complaints

NCT02122458
View directory record Official record
Conditions
Hearing Impairment, Hearing Aid Fitting
Interventions
mild-gain hearing aids with high-frequency emphasis over 6-months
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 50 Years
Enrollment
363 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
3
States / cities
Portland, Oregon • Pittsburgh, Pennsylvania • Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)

NCT04870008
View directory record Official record
Conditions
Suture, Dermatologic Surgery, Scar, Cosmetic Outcome
Interventions
Suture
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 2, 2021 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Not applicable Interventional Results available

Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities

NCT04545476
View directory record Official record
Conditions
Wound Heal
Interventions
Participants in this group will receive the experimental APIS Biomaterial on the Head., Participants in this group will receive the experimental APIS Biomaterial on the Lower Extremities., Standard Secondary Intention Healing on the Head, Standard Secondary Intention Healing on the Lower Extremities
Device · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 25, 2026, 4:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Traumatic Brain Injury Positive Strategies

NCT03867968
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
TIPS Intervention, Control
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Sep 25, 2026, 4:48 AM EDT
Not listed Not applicable Interventional

Effect of Blue Light Glasses on Screen Usage After a Concussion in College Students

NCT04804501
View directory record Official record
Conditions
Brain Concussion
Interventions
Blue Light Glasses, Computer Reading Task
Device · Other
Lead sponsor
Rochester Institute of Technology
Other
Eligibility
18 Years to 26 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Sep 25, 2026, 4:48 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Executive Dysfunction and Suicide in Psychiatric Outpatients and Inpatients

NCT01043432
View directory record Official record
Conditions
Traumatic Brain Injury, Suicidality
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 11, 2015 · Synced Sep 25, 2026, 4:48 AM EDT