- Conditions
- Muscle Spasticity, Hypertonia, Muscle, Cerebral Palsy, Multiple Sclerosis, Stroke, Hereditary Spastic Paraplegia, Dystonia, Spinal Cord Injuries
- Interventions
- MTR-601
- Drug
- Lead sponsor
- Motric Bio
- Industry
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 89 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
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Showing 1–24
of 1,044
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Spinal Cord Injuries, Autonomic Dysreflexia
- Interventions
- Mild Intermittent Hypoxia, Sham
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Spinal Cord Injury at C5-C7 Level, Spinal Cord Injuries, Spinal Cord Injury Cervical
- Interventions
- Networked Neuroprosthesis Device
- Device
- Lead sponsor
- MetroHealth Medical Center
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Obstructive Sleep Apnea, Hypercapnia, Spinal Cord Injury
- Interventions
- BiPAP, BiPAP/AVAPS (Phillips Respironics)
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 93 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Spinal Cord Injury
- Interventions
- Epidural Spinal Cord Stimulation System
- Device
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 22 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Spinal Cord Injuries, Stroke, Healthy Adults
- Interventions
- Alternating air wheelchair cushion, Static air cushion
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 20 Years to 85 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Flint, Michigan
- Conditions
- Spinal Cord Injuries, Cardiovascular Diseases, Endothelial Dysfunction
- Interventions
- Brachial intra-arterial infusion of vasoactive and antioxidant drugs (acetylcholine, nitroprusside, ascorbic acid), venous occlusion plethysmography, Acetylcholine, Sodium Nitroprusside, Ascorbic acid, venous phlebotomy
- Procedure · Drug
- Lead sponsor
- Craig Hospital
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Englewood, Colorado
- Conditions
- Spinal Cord Injury Cervical
- Interventions
- Blood flow-restricted resistance exercise
- Behavioral
- Lead sponsor
- Quality Living, Inc.
- Other
- Eligibility
- 19 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- SCI - Spinal Cord Injury
- Interventions
- Active VNS
- Device
- Lead sponsor
- The University of Texas at Dallas
- Other
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 2
- States / cities
- Dallas, Texas • Richardson, Texas
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia, Complex Regional Pain Syndromes, Post-Stroke Pain, Post Radiation Brain Injury, Post Radiation Plexopathy, Nerve Root Avulsion
- Interventions
- Medtronic Summit RC+S or Percept RC
- Device
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2030
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Spinal Cord Injury, Tetraplegia/Tetraparesis
- Interventions
- Up-conditioning of the wrist extensor motor evoked potential
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Spinal Cord Injury
- Interventions
- Body weight support treadmill training
- Procedure
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 16 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2004
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Spinal Cord Injury, Stroke, Amputees
- Interventions
- Therapy Sessions
- Device
- Lead sponsor
- Brooks Rehabilitation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Jacksonville, Florida • Tampa, Florida
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases, Cough, Trauma, Nervous System, Wounds and Injuries
- Interventions
- Spinal Cord Stimulation to restore cough, Expiratory Muscle Stimulator
- Procedure · Device
- Lead sponsor
- MetroHealth Medical Center
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2017
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Spinal Cord Injury, Acute, Spinal Cord Injury (SCI), Initial Encounter, Spinal Cord Injury Cervical
- Interventions
- Expansile duraplasty
- Procedure
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Spinal Cord Injuries, Constipation, Fecal Incontinence, Neurogenic Bowel
- Interventions
- Combination of Neostigmine and Glycopyrrolate, I-Box by Dynatronics
- Drug · Device
- Lead sponsor
- James J. Peters Veterans Affairs Medical Center
- Federal
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Spinal Cord Injury, Pressure Ulcers
- Interventions
- Education and Counseling
- Behavioral
- Lead sponsor
- US Department of Veterans Affairs
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 278 participants
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 6
- States / cities
- Augusta, Georgia • Memphis, Tennessee • Houston, Texas + 3 more
- Conditions
- Spinal Cord Injuries
- Interventions
- implanted epidural stimulator
- Device
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Spinal Cord Injury
- Interventions
- Surgery, IRS-8
- Procedure · Device
- Lead sponsor
- Case Western Reserve University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 2016
- U.S. locations
- 2
- States / cities
- Cleveland, Ohio
- Conditions
- Spinal Cord Injury
- Interventions
- Dalfampridine, Placebo drug, STDP stimulation, Exercise training
- Drug · Other · Behavioral
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Psychological Well-Being, Spinal Cord Injuries
- Interventions
- SCI Self-Management for AIS D
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- Not listed
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Spinal Cord Injury, Depression - Major Depressive Disorder, Veteran
- Interventions
- Psilocybin (Usona Institute)
- Drug
- Lead sponsor
- James J. Peters Veterans Affairs Medical Center
- Federal
- Eligibility
- 22 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Spinal Cord Injury (SCI)
- Interventions
- Locomotor Training
- Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 3 Years to 13 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2012
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Neurogenic Bowel Dysfunction
- Interventions
- Electrical Rectal Stimulation
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Syracuse, New York